Metformin+pioglitazone+sitagliptin
About Metformin+pioglitazone+sitagliptin
Metformin+pioglitazone+sitagliptin belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus. This condition causes blood sugar to be too high because the body does not normally produce or use insulin.
Metformin+pioglitazone+sitagliptin contains Metformin, Pioglitazone, and Sitagliptin. These drugs work by increasing the body’s response to insulin and decreasing the amount of glucose made by the liver and absorbed from food. Thus, it helps control blood sugar levels.
In some cases, Metformin+pioglitazone+sitagliptin may cause side effects such as nausea, stomach upset, diarrhoea, and headache. Most of these side effects may not require medical attention and resolve gradually over time. However, if any side effects persist or worsen, consult the doctor.
Do not take Metformin+pioglitazone+sitagliptin if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.
Uses of Metformin+pioglitazone+sitagliptin
Medicinal Benefits
Metformin+pioglitazone+sitagliptin is used to treat type-2 diabetes mellitus. It contains Metformin (biguanides), Pioglitazone (thiazolidinediones) and Sitagliptin (dipeptidyl peptidase-4 (DPP-4) inhibitors). Metformin increases the body’s response to insulin and decreases the amount of glucose absorbed from food and made by the liver. Pioglitazone enhances the body’s sensitivity to insulin. Sitagliptin increases certain natural substances in the body that lower blood glucose levels. Together, Metformin+pioglitazone+sitagliptin helps treat type 2 diabetes and prevents complications of diabetes such as kidney damage and nerve and eye problems.
Directions for Use
Storage
Side Effects of Metformin+pioglitazone+sitagliptin
- Nausea
- Stomach upset
- Headache
- Diarrhoea
Drug Warnings
Do not take Metformin+pioglitazone+sitagliptin if you are allergic to any of its components. Inform the doctor if you have type 1 diabetes, kidney or liver problems, diabetic ketoacidosis, heart problems, pancreatitis (inflammation of the pancreas), high triglycerides, gallstones, alcoholism, bladder cancer, eye problems caused by diabetes, bone problems, or if you use insulin. Consult the doctor if you are pregnant or breast-feeding. Let the doctor know if you are taking any other medicines, including supplements and herbal products.
Drug Interactions
Drug-Drug Interactions: Inform the doctor if you are taking anti-diabetic (insulin glargine, insulin degludec), diuretic (furosemide), hormone (levothyroxine), or anticonvulsant (pregabalin).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform the doctor if you have pancreatitis, congestive heart failure, type 1 diabetes, lactic acidosis, liver, or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid/limit alcohol consumption as it might affect blood sugar levels.
Pregnancy
consult your doctorPlease consult the doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe Metformin+pioglitazone+sitagliptin if the benefits outweigh the risks.
Breast Feeding
consult your doctorPlease consult your doctor if you are breastfeeding. Your doctor will decide whether Metformin+pioglitazone+sitagliptin can be taken during lactation.
Driving
consult your doctorIt is not known if Metformin+pioglitazone+sitagliptin affects your ability to drive. Drive or operate machinery only if you are alert.
Liver
consult your doctorPlease consult the doctor if you have a liver impairment or any concerns regarding this.
Kidney
consult your doctorPlease consult the doctor if you have kidney problems or any concerns regarding this.
Children
consult your doctorLimited information is available. Please consult the doctor if you have any concerns regarding the usage of Metformin+pioglitazone+sitagliptin in children.
Habit Forming
Diet & Lifestyle Advise
- Include fruits, vegetables, whole grains, and beans in your diet.
- Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
- Maintain a healthy weight by exercising regularly.
- Rest properly.
- Avoid stress by doing meditation or yoga.
- Limit saturated and processed food.
- Stay physically active as it helps manage blood glucose levels.
- Avoid/limit the consumption of alcohol as it may affect blood sugar levels.
Special Advise
- If you are due to undergo any tests or surgery, inform the doctor that you are taking Metformin+pioglitazone+sitagliptin.
- Regular monitoring of blood sugar levels is advised.
Patients Concern
Disease/Condition Glossary
Type-2 diabetes mellitus: Type-2 diabetes mellitus, also known as non-insulin-dependent diabetes or adult-onset diabetes, is a chronic or lifelong disease that keeps the body from utilising insulin (a hormone which controls sugar levels in your blood) properly. It is a medical condition in which blood glucose levels are above normal. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes; hence, it is also known as adult-onset diabetes. Type 2 diabetes symptoms include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.
FAQs
Metformin+pioglitazone+sitagliptin is used to treat type 2 diabetes mellitus. It helps manage blood sugar/glucose levels.
Metformin+pioglitazone+sitagliptin works by increasing the amount of insulin made by the body. Additionally, it also decreases the amount of glucose made by the liver and absorbed from food. Thereby, it helps lower blood glucose levels.
Do not stop taking Metformin+pioglitazone+sitagliptin without consulting your doctor, as it may cause an increase in blood glucose levels. Continue taking Metformin+pioglitazone+sitagliptin for as long as your doctor has prescribed it to you. Speak with your doctor if you experience any difficulty while taking Metformin+pioglitazone+sitagliptin.
Metformin+pioglitazone+sitagliptin may cause hypoglycaemia (low blood sugar) in some cases. Symptoms of low blood sugar are headache, dizziness, sweating, hunger, irritability, confusion, and fast heartbeat. If you experience these symptoms, eat or drink a fast-acting source of sugar such as candy, fruit juice, raisins or crackers.
