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Chlordiazepoxide+imipramine

About Chlordiazepoxide+imipramine

Chlordiazepoxide+imipramine is a combination medicine used to treat depression and anxiety. Depression is a mental health disorder characterised by a persistent and intense feeling of sadness. Anxiety is a feeling of fear, dread, and uneasiness.

Chlordiazepoxide+imipramine contains Chlordiazepoxide and Imipramine. Chlordiazepoxide increases the action of a chemical messenger called GABA, which suppresses the abnormal activity of nerve cells in the brain. Imipramine elevates the levels of chemical messengers in the brain that help regulate mood. Together, it helps treat depression and anxiety.

Sometimes, Chlordiazepoxide+imipramine may cause side effects such as dry mouth, tiredness, constipation, confusion, and weight gain. These side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, consult the doctor.

Tell the doctor if you are allergic to any components in Chlordiazepoxide+imipramine. Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Chlordiazepoxide+imipramine

Treatment of Depression and Anxiety

Medicinal Benefits

Chlordiazepoxide+imipramine is a combination medicine used to treat depression and anxiety. Chlordiazepoxide+imipramine contains Chlordiazepoxide (benzodiazepine) and Imipramine (tricyclic antidepressant). Chlordiazepoxide increases the action of a chemical messenger called GABA, which suppresses the abnormal activity of nerve cells in the brain. Imipramine elevates the levels of chemical messengers in the brain that help regulate mood. Together, it helps treat depression and anxiety.

Directions for Use

Swallow the medicine as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Chlordiazepoxide+imipramine

  • Dry mouth
  • Tiredness
  • Constipation
  • Confusion
  • Weight gain

Drug Warnings

Do not take Chlordiazepoxide+imipramine if you are allergic to its components. Inform the doctor if you have/had mood/mental disorders, alcoholism or drug addiction, liver or kidney disease, heart problems, stroke, seizures, overactive thyroid, narrow-angle glaucoma, problems with urination, if you are due to undergo any surgery or if you are taking or have taken MAOI (Monoamine oxidase inhibitors) in the past 14 days. If you have suicidal thoughts such as killing or harming yourself, seek medical attention immediately. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you take other medicines, including herbal products and supplements.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking anti-depressants (duloxetine, escitalopram, fluoxetine, sertraline), skeletal muscle relaxant (cyclobenzaprine), or anti-convulsant (topiramate, pregabalin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have closed-angle glaucoma, drug dependence, seizures, low blood pressure, liver or kidney problems, cardiovascular disease, or pheochromocytoma (tumour or the adrenal gland).

Drug-Drug Interactions Checker List:

  • DULOXETINE
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • CYCLOBENZAPRINE
  • TOPIRAMATE
  • PREGABALIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol during treatment with Chlordiazepoxide+imipramine as it may cause unpleasant side effects.

    • Safety Warning

      Pregnancy

      caution

      Limited information is available. Please consult the doctor if you are pregnant, think you may be pregnant or if you are trying to become pregnant.

    • Safety Warning

      Breast Feeding

      caution

      Limited information is available. Consult the doctor if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      It is not known if Chlordiazepoxide+imipramine affects your ability to drive. However, avoid driving or operating machinery unless you know how this medicine affects you.

    • Safety Warning

      Liver

      consult your doctor

      Limited information is available. Please consult the doctor if you have liver problems.

    • Safety Warning

      Kidney

      consult your doctor

      Limited information is available. Please consult the doctor if you have kidney impairment or any concerns.

    • Safety Warning

      Children

      consult your doctor

      Limited information is available. If you have any concerns about using Chlordiazepoxide+imipramine in children, please consult the doctor.

    Habit Forming

    Not enough scientific literature available around this hence it is best to consult your physician

    Diet & Lifestyle Advise

    • Maintaining a healthy diet and exercising regularly helps in improving overall health and boosts self-esteem.
    • Regularly attend therapy sessions.
    • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
    • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
    • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
    • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
    • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
    • Exercising helps in the production of the body’s natural anti-depressants. It also helps in relieving stress, improving mood, boosting self-esteem, and providing restful sleep.
    • Avoid smoking and alcohol consumption.
    • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

    Patients Concern

    Disease/Condition Glossary

    Depression: Depression is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, changes in appetite, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression. 

    Anxiety: It is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety is the body’s natural response to stress, in which the feeling of fear may be intense and debilitating. It is the most common form of emotional disorder and can affect anyone at any age. Anxiety may cause a panic attack, obsessive-compulsive disorder, and post-traumatic stress disorder. The exact cause of anxiety is unknown, but it might be due to genetic or environmental factors. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

    FAQs

    Chlordiazepoxide+imipramine is used to treat Depression and Anxiety.

    Chlordiazepoxide+imipramine works by increasing the chemical messengers in the brain that help regulate mood. Thereby, it helps treat anxiety and depression.

    Do not discontinue the medicine suddenly without consulting your doctor. To treat your condition effectually, continue taking Chlordiazepoxide+imipramine for as long as your doctor has prescribed. Speak with your doctor if you experience any difficulty while taking Chlordiazepoxide+imipramine.

    Dry mouth could be a side-effect of Chlordiazepoxide+imipramine. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and prevent mouth drying.

    Available Medicines for

    Chlordiazepoxide+imipramine

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