Ceftazidime+sulbactam
About Ceftazidime+sulbactam
Ceftazidime+sulbactam belongs to a class of medicines called antibiotics. Antibiotics are a type of medication that is used to treat bacterial infections of the urinary system, respiratory tract, abdomen, bones and joints. A bacterial infection is a situation in which dangerous bacteria colonize the body and cause infection.
Ceftazidime+sulbactam is a combination of Ceftazidime and Sulbactam, a beta-lactamase inhibitor. Ceftazidime works by inhibiting the synthesis of the bacterial cell wall, a protective structure essential for bacterial survival. This disruption weakens the cell wall, ultimately causing bacterial cell death. Sulbactam enhances the effectiveness of ceftazidime by inhibiting beta-lactamase enzymes, which bacteria produce to resist antibiotics.
Ceftazidime+sulbactam will be administered by a healthcare professional; do not self-administer. The common side effects of Ceftazidime+sulbactam are stomach pain, allergic reaction, diarrhoea, nausea and vomiting. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, inform your doctor immediately.
Inform your doctor about your medical history and any medications you are currently taking to prevent potential interactions. If you are pregnant or breastfeeding, please inform your doctor before taking Ceftazidime+sulbactam. Additionally, Ceftazidime+sulbactam should be used with caution in individuals with renal impairment or those with a history of Clostridium difficile-associated diarrhoea.
Uses of Ceftazidime+sulbactam
Medicinal Benefits
Ceftazidime+sulbactam contains Ceftazidime, a third-generation cephalosporin antibiotic, and Sulbactam, a beta-lactamase inhibitor. Ceftazidime works by inhibiting the bacterial cell wall, a structure essential for bacterial survival. This disruption weakens the cell wall, leading to the death of the bacteria. Beta-lactamase is an enzyme some bacteria produce that deactivates antibiotics, contributing to drug resistance. Sulbactam helps reduce this resistance while enhancing the effectiveness of Ceftazidime against bacteria. Together, Ceftazidime+sulbactam helps treat bacterial infections.
Directions for Use
Ceftazidime+sulbactam will be administered by a healthcare professional; Do not self-administer.
Storage
Side Effects of Ceftazidime+sulbactam
- Diarrhoea
- Nausea
- Vomiting
- Abdominal pain
- Dizziness
- Allergic reaction
Drug Warnings
Inform your doctor if you are allergic to Ceftazidime+sulbactam or other medications. If you have kidney issues, inform your doctor before using Ceftazidime+sulbactam. Consult your doctor if you are pregnant or breastfeeding. Since Ceftazidime+sulbactam may cause dizziness, drive only if you feel alert. It is important to complete the full course of Ceftazidime+sulbactam as prescribed by your doctor for effective results.
Drug Interactions
Drug-Drug Interaction: Ceftazidime+sulbactam may interact with aminoglycosides, diuretic or water pills (furosemide), and antibiotics (chloramphenicol).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have kidney problems, Ceftazidime+sulbactam should be used cautiously as it may require dose adjustments.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThe interaction of Ceftazidime+sulbactam with alcohol is unknown. Please consult a doctor before consuming alcohol while using Ceftazidime+sulbactam.
Pregnancy
cautionCeftazidime+sulbactam should be used in pregnancy only if clearly needed. If you are pregnant, inform your doctor beforehand.
Breast Feeding
cautionCeftazidime+sulbactam may be excreted in human milk in small amounts. If you are breastfeeding, inform your doctor beforehand. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
cautionCeftazidime+sulbactam may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Ceftazidime+sulbactam.
Liver
consult your doctorNo adjustment in dosage is required for patients with liver dysfunction. However, if you have liver problems, inform your doctor before receiving Ceftazidime+sulbactam.
Kidney
cautionCeftazidime+sulbactam should be used with caution in patients with kidney disease. Your doctor may initiate the treatment with low doses and adjust the dose gradually depending on the clearance of the medicine.
Children
cautionLimited information is available, so please consult a doctor about using Ceftazidime+sulbactam in children.
Habit Forming
Diet & Lifestyle Advise
- Probiotics should be taken after taking the entire course of Ceftazidime+sulbactam to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.
- Include more fibre-rich foods in your diet. They nourish and promote the growth of gut bacteria and restore a healthy gut microbiome after antibiotic use. Whole grains, such as whole-grain bread and brown rice, are excellent sources of dietary fiber and should be included in your meals.
- Make sure you drink plenty of water or other fluids every day while you are taking Ceftazidime+sulbactam.
- Avoid alcohol consumption as it may increase adverse effects.
Patients Concern
Disease/Condition Glossary
Bacterial Infection: A bacterial infection is a condition caused by harmful bacteria that enter and multiply in the body. These bacteria can produce toxins, which harm tissues and cause sickness. Bacterial infections are commonly associated with pneumonia, urinary tract infections, and skin infections. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue.
FAQs
Ceftazidime+sulbactam belongs to the class of medicines called antibiotics. It is used to treat bacterial infections of the urinary tract, respiratory tract, abdomen, bones, and joints.
Ceftazidime+sulbactam works by damaging the bacterial cell wall (protective covering) necessary for their survival and increasing bacterial sensitivity.
Ceftazidime+sulbactam may cause diarrhoea as a common side effect. However, if the condition persists or worsens, or you notice blood or mucus in stools, avoid taking Ceftazidime+sulbactam and consult a doctor immediately.
Ceftazidime+sulbactam is not used to treat viral infections; it is an antibiotic used only to treat bacterial infections.
Ceftazidime+sulbactam is administered through an IV (intravenous) or IM (intramuscular) route by a healthcare provider in a hospital or clinic. The dose and duration depend on the specific infection being treated. It should not be self-administered.
Ceftazidime+sulbactam typically starts working within one to two days after starting treatment. However, it may take several days to fully eliminate the bacteria, allowing you to feel better.
The common side effects of Ceftazidime+sulbactam include stomach pain, allergic reaction, nausea, diarrhoea, and vomiting. These side effects are often transient, and not everyone will experience them. In most situations, they resolve themselves without the need for medical intervention. However, if the adverse effects persist or worsen, please contact your doctor for further guidance and treatment.
