AMLODIPINE+BISOPROLOL FUMARATE
About
AMLODIPINE+BISOPROLOL FUMARATE is used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications. AMLODIPINE+BISOPROLOL FUMARATE lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future.
AMLODIPINE+BISOPROLOL FUMARATE contains Amlodipine and Bisoprolol fumarate. Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol fumarate helps in relaxing the blood vessels by blocking the action of certain natural substances in the body. Together, AMLODIPINE+BISOPROLOL FUMARATE helps treat high blood pressure.
You are advised to take AMLODIPINE+BISOPROLOL FUMARATE for as long as your doctor has prescribed, to treat your condition effectively. In some cases, AMLODIPINE+BISOPROLOL FUMARATE may cause side effects like headache, dizziness, palpitations, abdominal pain, ankle swelling, and oedema. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Avoid taking AMLODIPINE+BISOPROLOL FUMARATE if you are allergic to any of the components. Consult your doctor before starting AMLODIPINE+BISOPROLOL FUMARATE if you are pregnant or breastfeeding. AMLODIPINE+BISOPROLOL FUMARATE is not recommended for children below 18 years as the safety and effectiveness have not been established. AMLODIPINE+BISOPROLOL FUMARATE may cause dizziness, so drive only if you are alert. Avoid alcohol consumption along with AMLODIPINE+BISOPROLOL FUMARATE as it may potentiate the blood pressure-lowering effect of AMLODIPINE+BISOPROLOL FUMARATE.
Uses of AMLODIPINE+BISOPROLOL FUMARATE
Medicinal Benefits
AMLODIPINE+BISOPROLOL FUMARATE is a combination of two medicines: Amlodipine and Bisoprolol fumarate, which together help in lowering raised blood pressure effectively. Amlodipine is a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol fumarate (beta-blocker) helps in relaxing the blood vessels by blocking the action of certain natural substances in the body. Together, AMLODIPINE+BISOPROLOL FUMARATE lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future.
Directions for Use
Storage
Side Effects of AMLODIPINE+BISOPROLOL FUMARATE
- Headache
- Dizziness
- Palpitations
- Abdominal pain
- Oedema
- Ankle swelling
- Fatigue
- Cold extremities
- Nausea
- Vomiting
- Diarrhoea
- Constipation
In-Depth Precautions and Warning
Drug Warnings
Avoid taking AMLODIPINE+BISOPROLOL FUMARATE if you are allergic to any of the components. Inform your doctor if you have heart problems, diabetes, Prinzmetal angina, psoriasis, pheochromocytoma, very slow heartbeat, serious heart condition, heart blockage, kidney or liver problems, muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood pressure (hypotension), depression, previous heart failure, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome). Consult your doctor if you are pregnant or breastfeeding.
Drug Interactions
Drug-Drug Interaction: AMLODIPINE+BISOPROLOL FUMARATE may interact with other beta-blockers (acebutolol, atenolol, bisoprolol, carteolol, esmolol, metoprolol, nadolol, nebivolol or sotalol), anti-hypertensive drugs (aliskiren, amiloride, enalapril, captopril, quinapril, diltiazem), asthma medications (theophylline, aminophylline), potassium-rich supplements or any other pain killers (ibuprofen). If you are using these medicines, inform your doctor before taking AMLODIPINE+BISOPROLOL FUMARATE.
Drug-Food Interaction: AMLODIPINE+BISOPROLOL FUMARATE is known to interact with grapefruit and protein-enriched foods. Using AMLODIPINE+BISOPROLOL FUMARATE together with ayurvedic, homoeopathy, Unani, herbal supplements, or any other OTC items may decrease the effects of AMLODIPINE+BISOPROLOL FUMARATE. Hence, it is better to maintain at least 2 hours gap between the administration of AMLODIPINE+BISOPROLOL FUMARATE and these products.
Drug-Disease Interaction: Inform your doctor if you have diabetes, thyroid disease, asthma, cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are recommended not to consume alcohol along with AMLODIPINE+BISOPROLOL FUMARATE as it may potentiate the blood pressure-lowering effect of AMLODIPINE+BISOPROLOL FUMARATE.
Pregnancy
cautionConsult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribed only if the benefits outweigh the risks.
Breast Feeding
unsafeAMLODIPINE+BISOPROLOL FUMARATE is not recommended in breastfeeding mothers.
Driving
cautionAMLODIPINE+BISOPROLOL FUMARATE may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.
Liver
cautionAMLODIPINE+BISOPROLOL FUMARATE to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionAMLODIPINE+BISOPROLOL FUMARATE to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
unsafeAMLODIPINE+BISOPROLOL FUMARATE is not recommended in children as the safety and efficacy of AMLODIPINE+BISOPROLOL FUMARATE have not yet been established.
Habit Forming
Diet & Lifestyle Advise
- Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.
- Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Try to include heart-healthy omega 3 fatty acids containing food and drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil as they may help in lowering your elevated blood pressure.
Special Advise
Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day.
If you accidentally take an extra dose of AMLODIPINE+BISOPROLOL FUMARATE, please inform your doctor immediately. Some of the common symptoms of an overdose can be low blood pressure, slow pulse, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin.
Do not discontinue taking AMLODIPINE+BISOPROLOL FUMARATE abruptly or without the advice of the physician.
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.
FAQs
AMLODIPINE+BISOPROLOL FUMARATE is used to treat high blood pressure, a chronic condition in which the force exerted by the blood against the artery wall is high.
AMLODIPINE+BISOPROLOL FUMARATE works by reducing the workload on the heart and relaxing the blood vessels to ensure a fluid flow of blood. Thereby, lowering high blood pressure.
Do not stop taking AMLODIPINE+BISOPROLOL FUMARATE without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking AMLODIPINE+BISOPROLOL FUMARATE for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking AMLODIPINE+BISOPROLOL FUMARATE.
High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as AMLODIPINE+BISOPROLOL FUMARATE are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.
AMLODIPINE+BISOPROLOL FUMARATE may cause palpitations, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.
Try not to miss a dose in the first place. If you missed a dose of AMLODIPINE+BISOPROLOL FUMARATE, you are advised to take it as soon as you remember. However, if it is time for the scheduled dose, skip the missed dose and take the scheduled dose. Avoid taking a double dose of AMLODIPINE+BISOPROLOL FUMARATE as it may lead to low blood pressure.
No, AMLODIPINE+BISOPROLOL FUMARATE is not habit-forming. However, it is essential to use this medication under medical supervision and follow the prescribed dosage and duration.
Uncontrolled hypertension gradually destroys the arteries, causing them to harden. As the arteries constrict and become less flexible, the heart works harder to circulate blood. Uncontrolled high blood pressure can cause a stroke, heart attack, heart failure, and other heart problems, damage to the kidneys, memory, and eyesight, and contribute to erectile dysfunction.
Taking AMLODIPINE+BISOPROLOL FUMARATE may cause dizziness in some individuals. This medication can temporarily drop blood pressure, resulting in lightheadedness or dizziness, especially when standing up quickly or changing positions. The vasodilation effect of amlodipine and the heart rate slowing effect of bisoprolol can both contribute to this side effect. If you experience dizziness after taking this medication, it's essential to move slowly when standing up, avoid sudden changes in position, and sit or lie down if the dizziness occurs. If the dizziness persists or worsens, consult your doctor, as they may need to adjust your dosage or recommend alternative treatments. Remember to prioritize your safety and consult your healthcare provider if you have any concerns.
Store AMLODIPINE+BISOPROLOL FUMARATE at room temperature, away from heat and direct sunlight. When it's no longer needed or has expired, dispose of it responsibly. Check your local waste management guidelines for instructions. Make sure it is not consumed by children, pets, and other people.
The use of AMLODIPINE+BISOPROLOL FUMARATE is contraindicated to certain individuals. Those with a known hypersensitivity to amlodipine, bisoprolol, or any component of AMLODIPINE+BISOPROLOL FUMARATE should avoid using it. Additionally, it may not recommended for patients with cardiogenic shock, heart block (second or third-degree), sick sinus syndrome, or bradycardia (heart rate < 60 beats per minute) and pulmonary oedema (a condition characterized by fluid accumulation in the lungs). Furthermore, pregnant and breastfeeding women should not use this medication, as it may harm the fetus or baby. Finally, concurrent use with certain medications, such as beta-blockers, calcium channel blockers, digoxin, and catecholamine-depleting drugs, is also contraindicated. It's essential to consult a healthcare professional to discuss individual circumstances and determine if AMLODIPINE+BISOPROLOL FUMARATE is safe to use.
The use of AMLODIPINE+BISOPROLOL FUMARATE can lead to headaches in some individuals, typically due to the vasodilation effects of amlodipine, which can cause blood vessels to widen, or the beta-blocking effects of bisoprolol. While headaches are a common side effect in around 10-20% of patients, they are usually mild and temporary. If you experience a headache while taking this medication, In that case, it's essential to consult your healthcare provider to determine the best course of action, as they can recommend strategies to manage headaches or adjust your dosage if necessary and also rule out any underlying conditions or interactions with other medications.
Common side effects of AMLODIPINE+BISOPROLOL FUMARATE may include headache, dizziness, palpitations, abdominal pain, oedema, ankle swelling, fatigue, cold extremities, nausea, vomiting, diarrhoea, and constipation. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.
Use caution when driving or operating heavy machinery, as AMLODIPINE+BISOPROLOL FUMARATE may cause drowsiness or impaired coordination.
Limit alcohol intake or avoid it, as it may potentiate the blood pressure-lowering effects of AMLODIPINE+BISOPROLOL FUMARATE.
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
