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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Bisobis A 2.5 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. It is a combination medicine which suppress the contraction of blood vessels and promote smooth blood flow. It also alters the response to nerve impulses in the heart thereby making the heart pump blood easier. Common side effects include headache, nausea, dizziness, weakness, decreased blood pressure, and a slow heart rate.
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in last 90 days
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Manufacturer/Marketer :

Corona Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Bisobis A 2.5 Tablet

Bisobis A 2.5 Tablet is used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications. Bisobis A 2.5 Tablet  lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future. 

Bisobis A 2.5 Tablet contains Amlodipine and Bisoprolol fumarate. Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol fumarate helps in relaxing the blood vessels by blocking the action of certain natural substances in the body. Together, Bisobis A 2.5 Tablet helps treat high blood pressure.

You are advised to take Bisobis A 2.5 Tablet for as long as your doctor has prescribed, to treat your condition effectively. In some cases, Bisobis A 2.5 Tablet may cause side effects like headache, dizziness, palpitations, abdominal pain, ankle swelling, and oedema. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Avoid taking Bisobis A 2.5 Tablet if you are allergic to any of the components. Consult your doctor before starting Bisobis A 2.5 Tablet if you are pregnant or breastfeeding. Bisobis A 2.5 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Bisobis A 2.5 Tablet may cause dizziness, so drive only if you are alert. Avoid alcohol consumption along with Bisobis A 2.5 Tablet as it may potentiate the blood pressure-lowering effect of Bisobis A 2.5 Tablet .

Uses of Bisobis A 2.5 Tablet

Treatment of High Blood Pressure

Directions for Use

Swallow Bisobis A 2.5 Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Bisobis A 2.5 Tablet is a combination of two medicines: Amlodipine and Bisoprolol fumarate, which together help in lowering raised blood pressure effectively. Amlodipine is a calcium channel blocker that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol fumarate (beta-blocker) helps in relaxing the blood vessels by blocking the action of certain natural substances in the body. Together, Bisobis A 2.5 Tablet lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, other heart problems, or kidney problems in the future.

How Bisobis A 2.5 Tablet Works

Bisobis A 2.5 Tablet contains Amlodipine and Bisoprolol fumarate. Amlodipine acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Bisoprolol fumarate helps in relaxing the blood vessels by blocking the action of certain natural substances in the body. Together, Bisobis A 2.5 Tablet helps treat high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bisobis A 2.5 Tablet

  • Headache
  • Dizziness
  • Palpitations
  • Abdominal pain
  • Oedema
  • Ankle swelling
  • Fatigue
  • Cold extremities
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation

What if I have taken an overdose of Bisobis A 2.5 Tablet

Do not take more than the prescribed dose of Bisobis A 2.5 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Avoid taking Bisobis A 2.5 Tablet if you are allergic to any of the components. Inform your doctor if you have heart problems, diabetes, Prinzmetal angina, psoriasis, pheochromocytoma, very slow heartbeat, serious heart condition, heart blockage, kidney or liver problems, muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood pressure (hypotension), depression, previous heart failure, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome). Consult your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineMitotane
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Using Bisobis A 2.5 Tablet 10's together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Bisobis A 2.5 Tablet 10's with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Using Bisobis A 2.5 Tablet 10's and mitotane together may drastically lower Bisobis A 2.5 Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Bisobis A 2.5 Tablet 10's with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineLemborexant
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Coadministration of lemborexant and Bisobis A 2.5 Tablet 10's may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Bisobis A 2.5 Tablet 10's with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Using Bisobis A 2.5 Tablet 10's and primidone together may lower Bisobis A 2.5 Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Bisobis A 2.5 Tablet 10's with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Coadministration of Bisobis A 2.5 Tablet 10's and rifampicin together may lower Bisobis A 2.5 Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Bisobis A 2.5 Tablet 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Co-administration of Tizanidine and Bisobis A 2.5 Tablet 10's can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Bisobis A 2.5 Tablet 10's with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Coadministration of Bisobis A 2.5 Tablet 10's and Idelalisib may raise Bisobis A 2.5 Tablet 10's levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Bisobis A 2.5 Tablet 10's with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineRifabutin
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Using Bisobis A 2.5 Tablet 10's and rifabutin together may lower Bisobis A 2.5 Tablet 10's blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Bisobis A 2.5 Tablet 10's with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipineSirolimus
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Co-administration of Bisobis A 2.5 Tablet 10's can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Bisobis A 2.5 Tablet 10's and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineItraconazole
Severe
How does the drug interact with Bisobis A 2.5 Tablet 10's:
Coadministration of Bisobis A 2.5 Tablet 10's with itraconazole may significantly raise the blood levels and effects of Bisobis A 2.5 Tablet 10's.

How to manage the interaction:
Bisobis A 2.5 Tablet 10's and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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BISOPROLOL FUMARATE-2.5MG+AMLODIPINE-5MGFruit juices, Fruits
Mild

Drug-Food Interactions

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BISOPROLOL FUMARATE-2.5MG+AMLODIPINE-5MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit or grapefruit juice with Bisobis A 2.5 Tablet 10's can increase the blood levels of amlodipine. Avoid or limit consumption of grapefruit juice.

Diet & Lifestyle Advise

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week.
  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega 3 fatty acids containing food and drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil as they may help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Bisobis A 2.5 Tablet Substitute

Substitutes safety advice
  • Concor AM 2.5 Tablet 10's

    8.78per tablet
  • Stamlo Plus 2.5 Tablet 10's

    4.95per tablet
  • Besicor-AM 2.5 Tablet 10's

    9.58per tablet
  • Bisocut-AM 2.5 Tablet 15's

    5.85per tablet
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Alcohol

Caution

You are recommended not to consume alcohol along with Bisobis A 2.5 Tablet as it may potentiate the blood pressure-lowering effect of Bisobis A 2.5 Tablet .

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribed only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Bisobis A 2.5 Tablet is not recommended in breastfeeding mothers.

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Driving

Caution

Bisobis A 2.5 Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Bisobis A 2.5 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Bisobis A 2.5 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Bisobis A 2.5 Tablet is not recommended in children as the safety and efficacy of Bisobis A 2.5 Tablet have not yet been established.

FAQs

Bisobis A 2.5 Tablet is used to treat high blood pressure, a chronic condition in which the force exerted by the blood against the artery wall is high.
Bisobis A 2.5 Tablet works by reducing the workload on the heart and relaxing the blood vessels to ensure a fluid flow of blood. Thereby, lowering high blood pressure.
Do not stop taking Bisobis A 2.5 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Bisobis A 2.5 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Bisobis A 2.5 Tablet .
High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Bisobis A 2.5 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.
Bisobis A 2.5 Tablet may cause palpitations, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.
Try not to miss a dose in the first place. If you missed a dose of Bisobis A 2.5 Tablet , you are advised to take it as soon as you remember. However, if it is time for the scheduled dose, skip the missed dose and take the scheduled dose. Avoid taking a double dose of Bisobis A 2.5 Tablet as it may lead to low blood pressure.
No, Bisobis A 2.5 Tablet is not habit-forming. However, it is essential to use this medication under medical supervision and follow the prescribed dosage and duration.
Uncontrolled hypertension gradually destroys the arteries, causing them to harden. As the arteries constrict and become less flexible, the heart works harder to circulate blood. Uncontrolled high blood pressure can cause a stroke, heart attack, heart failure, and other heart problems, damage to the kidneys, memory, and eyesight, and contribute to erectile dysfunction.
Taking Bisobis A 2.5 Tablet may cause dizziness in some individuals. This medication can temporarily drop blood pressure, resulting in lightheadedness or dizziness, especially when standing up quickly or changing positions. The vasodilation effect of amlodipine and the heart rate slowing effect of bisoprolol can both contribute to this side effect. If you experience dizziness after taking this medication, it's essential to move slowly when standing up, avoid sudden changes in position, and sit or lie down if the dizziness occurs. If the dizziness persists or worsens, consult your doctor, as they may need to adjust your dosage or recommend alternative treatments. Remember to prioritize your safety and consult your healthcare provider if you have any concerns.
Store Bisobis A 2.5 Tablet at room temperature, away from heat and direct sunlight. When it's no longer needed or has expired, dispose of it responsibly. Check your local waste management guidelines for instructions. Make sure it is not consumed by children, pets, and other people.
The use of Bisobis A 2.5 Tablet is contraindicated to certain individuals. Those with a known hypersensitivity to amlodipine, bisoprolol, or any component of Bisobis A 2.5 Tablet should avoid using it. Additionally, it may not recommended for patients with cardiogenic shock, heart block (second or third-degree), sick sinus syndrome, or bradycardia (heart rate < 60 beats per minute) and pulmonary oedema (a condition characterized by fluid accumulation in the lungs). Furthermore, pregnant and breastfeeding women should not use this medication, as it may harm the fetus or baby. Finally, concurrent use with certain medications, such as beta-blockers, calcium channel blockers, digoxin, and catecholamine-depleting drugs, is also contraindicated. It's essential to consult a healthcare professional to discuss individual circumstances and determine if Bisobis A 2.5 Tablet is safe to use.
The use of Bisobis A 2.5 Tablet can lead to headaches in some individuals, typically due to the vasodilation effects of amlodipine, which can cause blood vessels to widen, or the beta-blocking effects of bisoprolol. While headaches are a common side effect in around 10-20% of patients, they are usually mild and temporary. If you experience a headache while taking this medication, In that case, it's essential to consult your healthcare provider to determine the best course of action, as they can recommend strategies to manage headaches or adjust your dosage if necessary and also rule out any underlying conditions or interactions with other medications.
Common side effects of Bisobis A 2.5 Tablet may include headache, dizziness, palpitations, abdominal pain, oedema, ankle swelling, fatigue, cold extremities, nausea, vomiting, diarrhoea, and constipation. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.
Use caution when driving or operating heavy machinery, as Bisobis A 2.5 Tablet may cause drowsiness or impaired coordination.
Limit alcohol intake or avoid it, as it may potentiate the blood pressure-lowering effects of Bisobis A 2.5 Tablet .
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

Corona House, Block C, Mondeal Business Park, Near Gurudwara,, S. G. Highway, Thaltej, Thaltej, Ahmedabad, Gujarat 380059
Other Info - BIS0212

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