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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:49 PM IST
Unithromb Ointment is used in the treatment of superficial thrombophlebitis. It contains Heparin and Benzyl nicotinate, which dissolves the blood clot and also prevents the formation of new blood clots. It can increase the blood flow to the affected area, thereby reducing the pain and inflammation. It may cause common side effects such as skin irritation, redness, burning sensation, and itching. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Unimarck Pharma India Ltd

Consume Type

TOPICAL

Return Policy

Not Returnable

About Unithromb Ointment

Unithromb Ointment belongs to the group of medications called ‘blood-related agents' used in the treatment of superficial thrombophlebitis. Superficial thrombophlebitis is a condition in which there are inflammation and swelling just below the surface of the skin due to the presence of a blood clot. This condition is usually formed in the legs or pelvic region. It is a short-term condition and symptoms include pain and tenderness in the affected area.

Unithromb Ointment is a combination of two medicines: Heparin and Benzyl nicotinate. Heparin is an anticoagulant and dissolves the blood clot. It also prevents the formation of new blood clots. Benzyl nicotinate is a vasodilator. It acts by widening the blood vessels and also improves skin oxygenation. Unithromb Ointment collectively can increase the blood flow to the affected area, thereby reducing the pain and inflammation.

You should take this medicine as advised by your doctor. The common side-effects of Unithromb Ointment are skin irritation, redness, burning sensation, and itching. These side-effects are usually mild and temporary. However, if any of these side-effects persist or worsen, consult your doctor immediately.

Do not take Unithromb Ointment if you are allergic to Heparin, Benzyl nicotinate, or any other ingredients present in it.  Unithromb Ointment is not recommended for use in open wounds, infected wounds, and skin ulcers and should be used with caution in people with blood disorders, sensitive skin, or undergoing surgery. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Unithromb Ointment

Treatment of Superficial Thrombophlebitis

Medicinal Benefits

Unithromb Ointment is a combination of two medicines: Heparin and Benzyl nicotinate. Heparin is an anticoagulant. It acts by breaking down the blood clot and preventing the formation of new blood clots. It also has anti-inflammatory properties and reduces swelling and inflammation. Benzyl nicotinate is a vasodilator and widens the blood vessels. It also promotes faster healing. Together, Unithromb Ointment can effectively improve the blood flow to the affected area and reduce the symptoms of superficial thrombophlebitis.

Directions for Use

Gently rinse the affected area with saline or water before applying Unithromb Ointment. Pat the skin and dry it with a clean cotton towel. Apply a generous amount of Unithromb Ointment and spread it evenly on the affected areas of the skin to form a 1/8-inch thick layer with clean and dry hands. You can also apply Unithromb Ointment with clean cotton wool or gauze swab. Wash your hands before and after using Unithromb Ointment on the affected areas unless the treatment is for hands.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Unithromb Ointment

  • Skin irritation
  • Skin redness
  • Burning sensation
  • Itching

Drug Warnings

Unithromb Ointment is for external use (skin) only. Do not apply it to the eyes, mouth, nose, genital area, or any broken skin. If the medicine accidentally comes in contact with the eyes, nose, or mouth, wash with water thoroughly and consult a doctor immediately. Do not apply for any other medicine at the treated area, unless prescribed by your doctor. Do not use for prolonged periods or more than the duration recommended by your doctor. It may cause photosensitivity (sensitivity to ultraviolet rays from the sun), so avoid sun lamps, tanning beds, and prolonged exposure to sunlight. Wear protective clothing such as a long-sleeved dress, sunglasses, and hat, and use sunscreen lotion with a high SPF if you are going outdoors in the daytime.

Drug Interactions

Drug-Drug interactions: Unithromb Ointment may interact with lipid-lowering drugs (fluvastatin, atorvastatin, and colestipol).

Drug-Food interactions: No interactions found.

Drug-Disease interactions: Unithromb Ointment should not be used in patients with open wounds and skin ulcers. It should be used with caution in patients with sensitive skin and blood disorders.

Drug-Drug Interactions Checker List

  • FLUVASTATIN
  • ATORVASTATIN
  • COLESTIPOL

Habit Forming

No

Diet & Lifestyle Advise

  • Take adequate bed rest.
  • Elevate legs while you are lying down as this may increase the blood flow to the legs.
  • Apply warm compresses to reduce pain and tenderness. It also helps to improve blood flow. 
  • Exercise regularly to maintain a normal weight, if you are obese. 
  • Follow a healthy diet.
  • Limit alcohol consumption and quit smoking

Special Advise

  • Avoid prolonged exposure under the sun or sunlamps, wear protective creams and clothing.

Disease/Condition Glossary

Superficial Thrombophlebitis: It is an inflammatory condition of veins occurring due to the formation of blood clots and blocking of one or more veins just below the surface of the skin. Symptoms include pain and tenderness in the affected region. It is often seen in the legs and pelvic region. However, arms and neck can also get affected occasionally. Women are most affected by this condition when compared to men. The causes of superficial thrombophlebitis are being immobile for longer durations (after surgery), varicose veins, pregnancy, clotting disorders, and obesity. It is a benign (not harmful) and short-term condition. It can resolve within 1 to 2 weeks with proper treatment.

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Alcohol

Safe if prescribed

Unithromb Ointment may not interact with alcohol.

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Pregnancy

Caution

There is no sufficient data available to establish safe use of Unithromb Ointment in pregnant women. So, please consult a doctor before taking Unithromb Ointment.

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Breast Feeding

Caution

There is no sufficient data available to establish safe use of Unithromb Ointment in breastfeeding mothers. So, please consult a doctor before taking Unithromb Ointment.

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Driving

Safe if prescribed

Unithromb Ointment may not affect your ability to drive.

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Liver

Safe if prescribed

Unithromb Ointment is probably safe in patients with liver diseases when prescribed.

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Kidney

Safe if prescribed

Unithromb Ointment is probably safe in patients with kidney diseases when prescribed.

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Children

Caution

There is no sufficient data available to establish the safe use of this medicine in children. So, please consult a doctor before taking Unithromb Ointment.

Country of origin

India

Manufacturer/Marketer address

503, Vishwadeep Tower, Janakpuri, Delhi - 110058, District Centre
Other Info - UN75218

Author Details

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FAQs

Unithromb Ointment belongs to the group of medications called 'blood-related agents'Â used to treat superficial thrombophlebitis. Superficial thrombophlebitis is a condition in which there is inflammation and swelling just below the surface of the skin due to a blood clot.
Unithromb Ointment is a combination of two medicines: Heparin and Benzyl nicotinate. Heparin is an anticoagulant and acts by dissolving the existing clots and preventing the formation of new blood clots. Benzyl nicotinate is a vasodilator (dilates the blood vessels). It improves blood flow to the affected area. Together, Unithromb Ointment can effectively reduce the symptoms of superficial thrombophlebitis such as pain and inflammation.
Unithromb Ointment is not recommended for the treatment of skin ulcers or open wounds. It can treat superficial thrombophlebitis, a condition characterized by pain and inflammation due to clot formation in the veins beneath the skin surface.
Unithromb Ointment may cause application-site reactions such as redness, itching, burning sensation, and irritation. These side-effects are usually mild and go away without any treatment. However, if any of these side-effects persist or get worse, consult a doctor immediately.
It is advised not to use Unithromb Ointment on broken skin and open wounds and make sure the medicine doesn’t come in contact with the eyes, nose, mouth, or genital area. It may increase skin sensitivity to the sun, so avoid prolonged sun exposure, tanning beds, and sun lamps. Wear protective clothing if you are going outdoors in the daytime.
Unithromb Ointment contains heparin, which is an anticoagulant (blood thinner). The use of heparin before surgery can lead to prolonged bleeding. However, this effect is seen mostly when heparin is taken in the tablet or injection form. So, it is recommended to inform your doctor before using Unithromb Ointment ointment if you are undergoing surgery.
If you're feeling better, don't stop taking your medicine! This is a crucial moment in your recovery. Stopping too soon can lead to incomplete recovery and return of symptoms. Instead, report your progress to your doctor and follow their advice. They will guide you on how to safely taper off medication if necessary, monitor for any potential side effects, and ensure the disease is fully cleared.
It is not recommended to use the Unithromb Ointment for heat boil. Unithromb Ointment is intended to treat superficial thrombophlebitis (inflammation of a vein near the skin's surface). If you're experiencing a heat boil, it's essential to consult a doctor for proper evaluation and treatment. They may recommend topical or oral antibiotics, pain management, or other treatments depending on the severity and location of the boil.
Unithromb Ointment, which combines Heparin and Benzyl Nicotinate, is not intended to treat piles (hemorrhoids). It's actually used to treat superficial thrombophlebitis and its related conditions.
Unithromb Ointment can help alleviate varicose vein symptoms like pain, inflammation, and poor blood flow. However, Unithromb Ointment should be taken only if the doctor advises you to use it to treat your condition.
Do not use Unithromb Ointment in babies or children below 18 years as safety and effectiveness have not been established.
Unithromb Ointment may help alleviate symptoms associated with strains, sprains, and bruises. However, it should be taken only if advised by the doctor after careful evaluation of your condition.
Unithromb Ointment may help reduce injection swelling after vaccination, but consult your doctor first. They will assess the swelling and recommend the best treatment, which may include Unithromb Ointment or other options.
Do not use Unithromb Ointment for acne and it is not intended to treat acne.
Burns are not usually treated with Unithromb Ointment. For treatment of burns, it is important to consult with a physician.
Unithromb Ointment is primarily used to treat superficial thrombophlebitis, an inflammation of the surface veins.
Consult your doctor before stopping Unithromb Ointment, even if your symptoms have improved. Your doctor will assess your condition and recommend the appropriate course of action, which may include continuing or tapering off the treatment to ensure optimal recovery and prevent recurrence.

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