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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Topnerve Tablet is a combination medicine used to manage diabetic neuropathy, neuropathic pain, and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, stomach upset, dizziness, and rash.

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Synonym :

ALPHA LIPOIC ACID+FOLIC ACID+MECOBALAMIN+PYRIDOXINE HYDROCHLORIDE+VITAMIN D3

Manufacturer/Marketer :

Vasu Organics Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Topnerve Tablet

Topnerve Tablet contains nutritional supplements used to treat neuropathic pain associated with diabetic neuropathy and nutritional deficiencies. Topnerve Tablet might help enhance blood calcium levels, fasten metabolism, facilitate the conversion of glucose into energy, helps improve the body’s oxidative stores, and develop healthy red blood cells. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. A nutritional deficiency occurs when the body does not absorb or get enough nutrients from food. 

Topnerve Tablet consists of five supplements: Alpha-lipoic acid, Methylcobalamin, Vitamin D3, Folic acid, and Pyridoxine. Methylcobalamin and pyridoxine help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant that prevents oxidative stress, thereby helping to provide a protective effect on the nerve tissues and brain. Vitamin D3 helps in resolving neuropathic symptoms and improves balance. Folic acid helps in providing essential nutrients. Together, Topnerve Tablet helps treat diabetic neuropathy and nutritional deficiencies. 

You are advised to take Topnerve Tablet for as long as your doctor has recommended it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach upset, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Consult your doctor before taking Topnerve Tablet if you are pregnant or breastfeeding. Limited information is available regarding the usage of Topnerve Tablet in children, so please consult a doctor. Drive only if you are alert as it is unknown if Topnerve Tablet affects your ability to drive. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Topnerve Tablet

Treatment of Diabetic neuropathy and nutritional deficiency

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Topnerve Tablet consists of five supplements: Alpha-lipoic acid, Methylcobalamin, Vitamin D3, Folic acid, and Pyridoxine. Topnerve Tablet is used to treat neuropathic pain and nutritional deficiencies. Methylcobalamin and pyridoxine help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Vitamin D3 helps in resolving neuropathic symptoms and improves balance. Alpha-lipoic acid is an antioxidant that prevents oxidative stress, thereby helping to provide a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Topnerve Tablet helps in providing relief from neuropathic pain.

How Topnerve Tablet Works

Topnerve Tablet consists of five supplements: Alpha-lipoic acid, Methylcobalamin, Vitamin D3, Folic acid, and Pyridoxine. Methylcobalamin and pyridoxine help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant that prevents oxidative stress, thereby helping to provide a protective effect on the nerve tissues and brain. Vitamin D3 helps in resolving neuropathic symptoms and improves balance. Folic acid helps in providing essential nutrients. Together, Topnerve Tablet helps treat diabetic neuropathy and nutritional deficiencies.

Storage

Store in a cool and dry place away from sunlight
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Side Effects of Topnerve Tablet

  • Diarrhoea
  • Stomach upset
  • Nausea
  • Vomiting

What if I have taken an overdose of Topnerve Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

Please do not take Topnerve Tablet if you are allergic to any of its contents. Inform your doctor before taking Topnerve Tablet if you have diabetes, thyroid problems, epilepsy, anaemia, infection, kidney or liver problems. Consult your doctor before taking Topnerve Tablet if you are pregnant or breastfeeding. Limited information is available regarding the usage of Topnerve Tablet in children, so please consult a doctor. Keep your doctor informed about your health condition and the medicines you are taking to rule out any interactions.

Drug-Drug Interactions

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ColecalciferolErgocalciferol
Severe
ColecalciferolSucralfate
Severe

Drug-Drug Interactions

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ColecalciferolErgocalciferol
Severe
How does the drug interact with Topnerve Tablet 10's:
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Topnerve Tablet 10's and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolSucralfate
Severe
How does the drug interact with Topnerve Tablet 10's:
Taking Cholecalciferol together with Sucralfate may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Cholecalciferol and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ColecalciferolCalcitriol
Severe
How does the drug interact with Topnerve Tablet 10's:
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Topnerve Tablet 10's and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolDoxercalciferol
Severe
How does the drug interact with Topnerve Tablet 10's:
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Topnerve Tablet 10's and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolDihydrotachysterol
Severe
How does the drug interact with Topnerve Tablet 10's:
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Topnerve Tablet 10's and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolParicalcitol
Severe
How does the drug interact with Topnerve Tablet 10's:
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Topnerve Tablet 10's and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolCalcifediol
Severe
How does the drug interact with Topnerve Tablet 10's:
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Topnerve Tablet 10's and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolAluminium hydroxide
Severe
How does the drug interact with Topnerve Tablet 10's:
The combined use of aluminum hydroxide with Topnerve Tablet 10's may increase the risk of toxicity.

How to manage the interaction:
Co-administration of Topnerve Tablet 10's with Aluminium hydroxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
Folic acidCapecitabine
Severe
How does the drug interact with Topnerve Tablet 10's:
Co-administration of Topnerve Tablet 10's with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Topnerve Tablet 10's and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
Folic acidColestyramine
Severe
How does the drug interact with Topnerve Tablet 10's:
Coadministration of Topnerve Tablet 10's and Cholestyramine may interfere with the absorption of Topnerve Tablet 10's.

How to manage the interaction:
Although taking Cholestyramine and Topnerve Tablet 10's together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT

Topnerve Tablet Substitute

Substitutes safety advice
  • Renerve D Tablet 15's

    16.20per tablet
  • Nervz D Tablet 10's

    by AYUR

    16.92per tablet
  • Renyle-D Tablet 10's

    by AYUR

    15.30per tablet
  • Mylomax Tablet 10's

    13.86per tablet
  • Hosit D3 Tablet 10's

    by AYUR

    21.96per tablet
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Alcohol

Caution

It is not known if alcohol interacts with Topnerve Tablet , so please consult a doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will advise only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Topnerve Tablet ; your doctor will decide whether Topnerve Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

It is unknown if Topnerve Tablet affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Limited information is available regarding the usage of Topnerve Tablet in patients with liver problems. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Limited information is available regarding the usage of Topnerve Tablet in patients with kidney problems. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Limited information is available regarding the usage of Topnerve Tablet in children, so please consult a doctor.

FAQs

Topnerve Tablet contains nutritional supplements used to treat neuropathic pain associated with diabetic neuropathy and dietary deficiencies.
Topnerve Tablet consists of Methylcobalamin, Vitamin D3, Alpha-lipoic acid, Folic acid, and Pyridoxine. These constituents help reduce nerve pain and nerve damage in neuropathy. It works by improving blood circulation to peripheral body parts and thus relieving pain.
To treat your condition effectually, continue taking Topnerve Tablet for as long as recommended. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Topnerve Tablet .
Diarrhoea could be a side-effect of Topnerve Tablet . Eat non-spicy meals and drink plenty of fluids if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.
Topnerve Tablet may be used as adjuvant therapy for diabetic patients suffering from diabetic neuropathy. However, you are advised to consult a doctor before taking Topnerve Tablet if you are diabetic. Topnerve Tablet contains alpha-lipoic acid, which might cause low blood sugar. Regularly monitor blood glucose levels while taking Topnerve Tablet .

Country of origin

INDIA

Manufacturer/Marketer address

Vasu's Pharma House, #3-6-516/4, 5th Floor, St, No.6, Himayath Nagar, Hyderabad - 500 029
Other Info - TOP0341

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