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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:23 PM IST
SILVER SULPHADIAZINE CREAM is used to treat bacterial infections and wound infections caused by serious burns. It is also used to treat infected leg ulcers and pressure sores. It contains Silver sulfadiazine which works by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as burning, irritation, itching, and redness at the application site. It is for external use only.
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Prescription drug

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Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About SILVER SULPHADIAZINE CREAM

SILVER SULPHADIAZINE CREAM is an antibiotic medication primarily used to treat bacterial infections and wound infections caused by serious burns. SILVER SULPHADIAZINE CREAM is also used to treat infected leg ulcers and pressure sores. A burn is damage to the skin or deeper tissues caused by hot liquids, fire, electricity, and chemicals. The degree of severity of burns is based on the size and depth of the burn.

SILVER SULPHADIAZINE CREAM contains Silver Sulfadiazine, which belongs to the class of 'sulfa antibiotics.' It is bactericidal (kills bacteria) and is also effective against yeast. It inhibits the production of folic acid, a nutrient required for bacterial multiplication and acts on the bacterial cell wall and cell membrane. This helps decrease the risk of the bacteria spreading to the surrounding skin or the blood that causes a severe blood infection (sepsis). 

SILVER SULPHADIAZINE CREAM is for external use only. SILVER SULPHADIAZINE CREAM has common side effects that include burning, irritation, itching, and redness at the application site. These side effects gradually resolve during the treatment and do not require medical attention.

Please cover the burn wounds with SILVER SULPHADIAZINE CREAM all the time and cover the treated area with dressings or bandages if advised by your doctor. Let your doctor know if you have glucose-6-phosphate dehydrogenase (a genetic enzyme) deficiency, low white blood cell count, liver and kidney problems before using SILVER SULPHADIAZINE CREAM . Please consult your doctor if you are pregnant or planning to conceive before using SILVER SULPHADIAZINE CREAM since it may affect the unborn baby. It is advised to seek medical advice if you are a breastfeeding mother before you use SILVER SULPHADIAZINE CREAM . 

Uses of SILVER SULPHADIAZINE CREAM

Treatment of Bacterial infections, and burns.

Medicinal Benefits

SILVER SULPHADIAZINE CREAM is used to treat bacterial infections, burns, and wound infections. It consists of Silver Sulfadiazine. It shows the bactericidal (kills bacteria) effect on many gram-negative and gram-positive bacteria and is also effective against yeast. It prevents the bacteria from producing folic acid, a nutrient required for bacterial multiplication and acts upon bacterial cell wall and cell membrane. This helps decrease the risk of the bacteria spreading to the surrounding skin or the blood that causes a severe blood infection (sepsis). 

Directions for Use

Ointment/Cream: SILVER SULPHADIAZINE CREAM is for external use only. Apply the advised amount of cream/ointment with the help of an applicator or a clean cotton ball or swab on the affected areas. Wash your hands before and after using SILVER SULPHADIAZINE CREAM if your hands are not the affected area to prevent the spread of infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of SILVER SULPHADIAZINE CREAM

  • Burning
  • Irritation
  • Itching
  • Redness at the application site 

Drug Warnings

Wear sterile disposable gloves if you apply SILVER SULPHADIAZINE CREAM for others and keep the treated area clean to prevent further infection. Do not apply SILVER SULPHADIAZINE CREAM in large amounts or use it for a longer time than advised, as it does not give quick or better results but increases the risk of side effects. Please cover the burn wounds with SILVER SULPHADIAZINE CREAM all the time and cover the treated area with dressings or bandages if advised by your doctor. Brief your medical history to the doctor if you have 6-phosphate dehydrogenase (a genetic enzyme) deficiency, low white blood cell count (leukopenia), liver, and kidney problems. Please consult your doctor if you are pregnant or planning to conceive before using SILVER SULPHADIAZINE CREAM . It is advised to seek medical advice before using SILVER SULPHADIAZINE CREAM if you are a breastfeeding mother.

Drug Interactions

Drug-Drug Interaction: SILVER SULPHADIAZINE CREAM may interact with anti-diabetics, local anaesthetics (benoxinate, benzocaine, cocaine, dibucaine, lidocaine, prilocaine, proparacaine, tetracaine), fits medicines (phenytoin), anti-ulcer drugs (cimetidine), enzymes (collagenase), and antioxidants (sodium nitrite).

Drug-Food Interaction: No interaction found/established. 

Drug-Disease Interaction: Before using SILVER SULPHADIAZINE CREAM , let your doctor know if you have any allergic reactions to SILVER SULPHADIAZINE CREAM , glucose-6-phosphate dehydrogenase (a genetic enzyme) deficiency, kidney or liver problems, and low white blood cell count.

Drug-Drug Interactions Checker List

  • BENOXINATE
  • BENZOCAINE
  • COCAINE
  • DIBUCAINE
  • LIDOCAINE
  • PRILOCAINE
  • PROPARACAINE
  • TETRACAINE
  • PHENYTOIN
  • CIMETIDINE
  • COLLAGENASE
  • SODIUM NITRITE

Habit Forming

No

Diet & Lifestyle Advise

  • Cool down the burn immediately by placing it under running water or apply a cool and wet compress until the pain decreases.

  • Remove any accessories like jewellery, belts, and tight clothing you are wearing since burns can swell quickly.

  • Consider getting a tetanus shot.

  • Avoid harsh products on your skin.

  • Do not scratch or pick your skin to avoid getting the affected area infected.

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

  • Do not walk barefoot at places like gym showers to prevent bacterial infections.

Disease/Condition Glossary

Skin infection: A skin infection can occur when the skin is broken, cut or wounded. This skin infection allows pathogenic microorganisms to enter and invade the tissues surrounding the wound. Infection of the wound can trigger the body's immune response, causing inflammation and tissue damage and eventually slowing down the healing process. 

Burn: A burn is a damage to the skin or deeper tissues that can be caused by hot liquids, fire, electricity, and chemicals. The degree of severity of burns is based on the size and depth of the burn.

Bacterial infection: Bacterial infection occurs when harmful bacteria grow in the body and causes illness. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have a cell wall).

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Alcohol

Caution

The interaction of SILVER SULPHADIAZINE CREAM with alcohol is unknown. Please consult a doctor before consuming alcohol while using SILVER SULPHADIAZINE CREAM .

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Pregnancy

Caution

There is limited information on how SILVER SULPHADIAZINE CREAM affects pregnancy. Please consult a doctor if you are pregnant before using SILVER SULPHADIAZINE CREAM .

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Breast Feeding

Caution

Please consult your doctor before using SILVER SULPHADIAZINE CREAM if you are breastfeeding. However, if you need to apply SILVER SULPHADIAZINE CREAM to your breasts, do not do it shortly before feeding your baby.

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Driving

Safe

SILVER SULPHADIAZINE CREAM is generally safe to use before driving. However, if you notice any side effects like dizziness or burning sensation in the affected areas, avoid driving and operating machinery until you feel better.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using SILVER SULPHADIAZINE CREAM .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using SILVER SULPHADIAZINE CREAM .

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Children

Caution

SILVER SULPHADIAZINE CREAM is not recommended for premature babies or any child younger than two months old. Your doctor will advise SILVER SULPHADIAZINE CREAM depending on your child's severity of burns or wounds.

Country of origin

India

Manufacturer/Marketer address

No. 41, 3rd Cross, 5th Block, Rajajinagar, Bengaluru – 560 010, Karnataka , India
Other Info - SIL0045

FAQs

SILVER SULPHADIAZINE CREAM consists of Silver Sulfadiazine (antibiotic). It prevents and treats severe wound infections on skin areas with burns. It works by killing the bacteria and preventing its multiplication on the skin surface.
SILVER SULPHADIAZINE CREAM may cause itching of the skin at the site of application as a temporary side effect. However, if the itching persists or worsens, please consult a doctor.
SILVER SULPHADIAZINE CREAM should be used with proper caution and doctor consultation if you have any glucose-6-phosphate dehydrogenase (a genetic enzyme) deficiency, low white blood cell count (Leukopenia), liver and kidney problems.
Store SILVER SULPHADIAZINE CREAM at room temperature. Do not freeze and protect from heat. Keep SILVER SULPHADIAZINE CREAM away from sunlight and temperatures not exceeding 30°C.
Your doctor will decide on the duration of using SILVER SULPHADIAZINE CREAM . Please do not stop using SILVER SULPHADIAZINE CREAM until your course is completed. If you do not notice any improvement even after a week, please seek medical advice. If you also experience any unusual side effects like fever, nausea, difficulty breathing, and swelling of the skin and mucosa, please stop using SILVER SULPHADIAZINE CREAM and consult your doctor.
No, do not stop using SILVER SULPHADIAZINE CREAM without consulting your doctor, even if you feel better. Please complete the course as prescribed by your doctor.
SILVER SULPHADIAZINE CREAM starts working quickly, but it may take a few days to fully eliminate the bacteria and relieve symptoms. Continue using SILVER SULPHADIAZINE CREAM as prescribed by your doctor and consult your doctor if you have concerns regarding it.
The common side effects of SILVER SULPHADIAZINE CREAM include burning sensation, irritation, itching, and redness at the application site. These side effects gradually resolve during the treatment and do not require medical attention. However, consult the doctor if the side effects persist or worsen.

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