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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Pegeze Syrup is used to treat constipation. It works by drawing water into the intestine; this softens the stools making it easier to pass. In some cases, this medicine may cause side effects such as stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About Pegeze Syrup

Pegeze Syrup belongs to a class of drugs called laxatives used to treat constipation. Constipation refers to infrequent bowel movements in which the stools are often dry, painful, and hard to pass.

Pegeze Syrup is a combination of four drugs, namely Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegeze Syrup helps in relieving constipation.

Take Pegeze Syrup as advised by your doctor. In some cases, you may experience stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Most of these side effects of Pegeze Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Pegeze Syrup or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking Pegeze Syrup . Pegeze Syrup is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking Pegeze Syrup . Drink plenty of fluids while taking Pegeze Syrup . Do not take Pegeze Syrup in more than the recommended doses.

Uses of Pegeze Syrup

Treatment of Constipation

Directions for Use

Oral solution: Dilute it with water as advised by your doctor. Take it by mouth using the measuring cup provided with the pack. Shake the bottle well before each use.Sachet: Dissolve the contents of sachet in water as advised by the doctor. Drink it.

Medicinal Benefits

Pegeze Syrup contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Also, it works by cleaning stool from the gastrointestinal tract. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegeze Syrup helps in comfortable bowel movement and provides relief from constipation.

How Pegeze Syrup Works

Pegeze Syrup is a combination of four drugs, namely Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegeze Syrup helps in relieving constipation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pegeze Syrup

  • Stomach pain
  • Indigestion
  • Mild diarrhoea
  • Nausea
  • Vomiting

What if I have taken an overdose of Pegeze Syrup

Take Pegeze Syrup only as advised by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Pegeze Syrup or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking Pegeze Syrup . Pegeze Syrup is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking Pegeze Syrup . Drink plenty of fluids while taking Pegeze Syrup . Do not take Pegeze Syrup in more than the recommended doses. Discard Pegeze Syrup after 30 days of first opening the bottle. Do not freeze or refrigerate Pegeze Syrup .

Drug-Drug Interactions

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Potassium chlorideSolifenacin
Critical
Potassium chlorideTrihexyphenidyl
Critical

Drug-Drug Interactions

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Potassium chlorideSolifenacin
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Solifenacin and Pegeze Syrup 200 ml together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Solifenacin with Pegeze Syrup 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideTrihexyphenidyl
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Co-administration of trihexyphenidyl with Pegeze Syrup 200 ml can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking trihexyphenidyl with Pegeze Syrup 200 ml is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black stools contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
Potassium chloridePhenindamine
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Phenindamine and Pegeze Syrup 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Phenindamine with Pegeze Syrup 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideOlanzapine
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Olanzapine with Pegeze Syrup 200 ml can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Olanzapine and Pegeze Syrup 200 ml is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Potassium chlorideDarifenacin
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Darifenacin with Pegeze Syrup 200 ml(oral capsule or tablet) can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darifenacin with Pegeze Syrup 200 ml(oral capsule or tablet) is not recommended, as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medications without doctor's advise.
Potassium chlorideTolterodine
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Tolterodine and Pegeze Syrup 200 ml together can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tolterodine and Pegeze Syrup 200 ml, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or less desire to eat. Do not discontinue medications without consulting a doctor.
Potassium chlorideClemastine
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Clemastine and Pegeze Syrup 200 ml(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Clemastine with Pegeze Syrup 200 ml is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideEplerenone
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Using Eplerenone together with Pegeze Syrup 200 ml may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking Pegeze Syrup 200 ml with eplerenone is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
Potassium chlorideOxybutynin
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Coadministration of Oxybutynin with Pegeze Syrup 200 ml can increase the risk of developing stomach ulcers.

How to manage the interaction:
Taking Oxybutynin with Pegeze Syrup 200 ml is generally avoided as it can lead to an interaction, it can be taken when a doctor has prescribed it. Consult the doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medication without contacting a doctor.
Potassium chlorideclidinium bromide
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Pegeze Syrup 200 ml with clidinium bromide may increase the risk of irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Pegeze Syrup 200 ml with clidinium bromide is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms such as severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), decreased hunger, black, tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try maintaining a balanced diet, which includes fresh fruits and vegetables.
  • Stay hydrated, and drink enough water and fluids.
  • Exercise regularly, and stay fit.
  • Get enough sleep.
  • Eat food rich in fibre, such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados).

Habit Forming

No

Therapeutic Class

LAXATIVES

Pegeze Syrup Substitute

Substitutes safety advice
  • Pegdeal Sugar Free Oral Solution 200 ml

    1.88per tablet
  • Pegday Sugar Free Oral Solution 100 ml

    1.78per tablet
  • Apeg Sugar Free Orange Flavour Oral Solution 200 ml

    1.40per tablet
  • Laxipeg Powder For Oral Solution Sachet 13.81 gm

    4.81per tablet
  • Hypanto PG Sugar Free Orange Flavour Oral Solution 200 ml

    1.75per tablet
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Alcohol

Caution

Interaction of alcohol with Pegeze Syrup is unknown. Please consult a doctor before consuming alcohol while using Pegeze Syrup .

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Pegeze Syrup is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. Pegeze Syrup is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe

Pegeze Syrup usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Pegeze Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Pegeze Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Pegeze Syrup is not recommended for children below 12 years of age as the safety and effectiveness were not established.

FAQs

Pegeze Syrup belongs to a class of drugs called laxatives used to treat constipation.
Pegeze Syrup contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools making it easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegeze Syrup helps in relieving constipation.
Pegeze Syrup may cause mild diarrhoea as a side effect in the beginning of the treatment. It usually gets better by reducing the amount of Pegeze Syrup intake. However, if the condition persists or worsens, please consult a doctor.
You are not recommended to take Pegeze Syrup with anticonvulsants as it may reduce the effectiveness of anticonvulsants (medicines for epilepsy). However, please consult your doctor before taking Pegeze Syrup with other medicines.
You are recommended to avoid foods that are high in fat and low in fiber such as ice cream, red meat, frozen meals, potato chips, cheese, hot dogs and hamburgers.
You are not recommended to take more than the advised dose of Pegeze Syrup as it may cause excessive diarrhoea that might lead to dehydration. If you have diarrhoea, stop taking Pegeze Syrup and drink plenty of fluids to avoid dehydration. However, if the condition persists or worsens, please consult a doctor.

Country of origin

INDIA

Manufacturer/Marketer address

S-14, 1St Floor, Janta Market, Rajouri Garden, New Delhi, 110 027
Other Info - PEG0089

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