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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Pegalup Oral Solution belongs to the class of medicines called stimulant laxatives used to cleanse the colon before a colonoscopy or barium enema. This combination medicines increases the intestine's water content and stimulates bowel movement, thereby, helps to cleanse the large intestine. Common side effects include diarrhoea, gastrointestinal pain/cramps, and abdominal discomfort.
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About Pegalup Oral Solution

Pegalup Oral Solution belongs to the class of medicines called stimulant laxatives used to cleanse the colon before a colonoscopy or barium enema (an x-ray test that determines abnormalities in the colon). Colonoscopy or barium enema is a procedure that involves inserting a flexible fibre-optic device into the anus to inspect the colon for identifying the extent of various diseases present in the large intestine or colon.

Pegalup Oral Solution contains Polyethylene glycol 3350, Sodium chloride, Sodium hydrogen carbonate, and Potassium chloride. Together, these salts increase the water content in the intestine and stimulate bowel movement. Thereby, Pegalup Oral Solution  helps to cleanse the large intestine so that the colonoscopy can be performed comfortably. Pegalup Oral Solution is rich in mineral salts that replaces lost electrolytes and prevent dehydration.

Take Pegalup Oral Solution exactly as directed. Certain typical side effects, such as diarrhoea, gastrointestinal pain/cramps, and abdominal discomfort, may occur in some circumstances. Most of these side effects do not necessitate medical treatment and will subside gradually over time. However, if you are experiencing these side effects regularly, you should consult your doctor.

Consult your doctor before taking Pegalup Oral Solution if you are pregnant or breastfeeding. Let your doctor know if you have gastrointestinal obstruction, bowel perforation, and gastric retention. Drink plenty of fluids whilst taking Pegalup Oral Solution to prevent dehydration. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects.

Uses of Pegalup Oral Solution

Used to cleanse the colon (bowel) for colonoscopy and barium enema

Directions for Use

Pegalup Oral Solution should be used strictly as directed by the doctor. Read the label carefully and follow the directions for use. Mix Pegalup Oral Solution with water and consume it as advised by the doctor.

Medicinal Benefits

Pegalup Oral Solution is a stimulant laxative used to clear the bowel before medical procedures such as colonoscopy or barium enema. It works by increasing water retention in the intestine, which causes a bowel movement. This clears the colon so that the colonoscopy can be performed easily. Pegalup Oral Solution is rich in mineral salts that replaces lost electrolytes and prevent dehydration.

How Pegalup Oral Solution Works

Pegalup Oral Solution contains Polyethylene glycol 3350, Sodium chloride, Sodium hydrogen carbonate, and Potassium chloride. Together, these salts increase the water content in the intestine and stimulate bowel movement. Thereby, Pegalup Oral Solution  helps to cleanse the large intestine so that the colonoscopy can be performed comfortably. Pegalup Oral Solution is rich in mineral salts that replaces lost electrolytes and prevent dehydration.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pegalup Oral Solution

  • Abdominal pain/cramps

  • Diarrhoea

  • Abdominal discomfort

What if I have taken an overdose of Pegalup Oral Solution

Do not take more than the prescribed dose of Pegalup Oral Solution as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use this medication without a doctor's prescription to treat constipation though it is laxative medicine. It is not intended to treat constipation. It is intended to cleanse the colon (bowel) before a colonoscopy. If you are pregnant or breastfeeding, seek medical advice from your doctor before using Pegalup Oral Solution . Inform your doctor if you have gastrointestinal obstruction, bowel perforation, and gastric retention. Before taking Pegalup Oral Solution , make sure your doctor knows your medical history and other medications you are taking. This will help to rule out any potential side effects.

Drug-Drug Interactions

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Potassium chlorideOxybutynin
Critical
Potassium chloridePhenindamine
Critical

Drug-Drug Interactions

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Potassium chlorideOxybutynin
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Coadministration of Oxybutynin with Pegalup Oral Solution 200 ml can increase the risk of developing stomach ulcers.

How to manage the interaction:
Taking Oxybutynin with Pegalup Oral Solution 200 ml is generally avoided as it can lead to an interaction, it can be taken when a doctor has prescribed it. Consult the doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medication without contacting a doctor.
Potassium chloridePhenindamine
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Phenindamine and Pegalup Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Phenindamine with Pegalup Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideSolifenacin
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Solifenacin and Pegalup Oral Solution 200 ml together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Solifenacin with Pegalup Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideTrospium
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Trospium with Pegalup Oral Solution 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Trospium with Pegalup Oral Solution 200 ml is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideEplerenone
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Using Eplerenone together with Pegalup Oral Solution 200 ml may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking Pegalup Oral Solution 200 ml with eplerenone is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
Potassium chlorideDiphenhydramine
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Diphenhydramine with Pegalup Oral Solution 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Diphenhydramine with Pegalup Oral Solution 200 ml is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, contact your doctor. Do not stop taking any medication without consulting your doctor.
Potassium chlorideGlycopyrrolate
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Glycopyrrolate with Pegalup Oral Solution 200 ml can increase the risk or severity of ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Glycopyrrolate with Pegalup Oral Solution 200 ml together is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Potassium chlorideChlorpheniramine
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Chlorpheniramine and Pegalup Oral Solution 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Chlorpheniramine with Pegalup Oral Solution 200 ml it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
Potassium chlorideDexchlorpheniramine
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Dexchlorpheniramine and Pegalup Oral Solution 200 ml can increase the risk of stomach inflammation.

How to manage the interaction:
Taking Dexchlorpheniramine with Pegalup Oral Solution 200 ml (in tablet or capsule form) is avoided as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, lightheadedness, vomiting, or dark stools, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Potassium chlorideClemastine
Critical
How does the drug interact with Pegalup Oral Solution 200 ml:
Taking Clemastine and Pegalup Oral Solution 200 ml(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Clemastine with Pegalup Oral Solution 200 ml is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try maintaining a balanced diet that includes fresh fruits and vegetables.

  • Stay hydrated drink enough water and fluids.

  • Exercise regularly and stay fit.

  • Get enough sleep.

  • Try making time to empty your bowels whenever the body tells you to.

  • Eat fibre-rich foods such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados).

Habit Forming

No

Therapeutic Class

LAXATIVES
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Alcohol

Caution

It is not known if alcohol interacts with Pegalup Oral Solution . However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

Pegalup Oral Solution should be used in pregnant women only if clinically needed, and benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pegalup Oral Solution if you are breastfeeding. Your doctor will decide if it can be taken by breastfeeding mothers or not.

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Driving

Caution

Pegalup Oral Solution is unlikely to affect your ability to drive. However, drive only if you are alert.

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Liver

Caution

If you have liver illness or impairment, talk to a doctor before taking Pegalup Oral Solution . Your doctor will only provide a prescription if the benefits outweigh the risks.

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Kidney

Caution

If you have kidney illness or impairment, talk to a doctor before taking Pegalup Oral Solution . Your doctor will only provide a prescription if the benefits outweigh the risks.

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Children

Caution

Pegalup Oral Solution should be given to children only if advised by the doctor.

FAQs

Pegalup Oral Solution belongs to the class of medicines called stimulant laxatives used to cleanse the colon before a colonoscopy or barium enema (an x-ray test that determines abnormalities in the colon).
Pegalup Oral Solution works by increasing water retention in the intestine, causing a bowel movement. This clears the colon, making it easier to do the colonoscopy.
Diarrhoea might occur if Pegalup Oral Solution is taken in larger doses. Stop taking Pegalup Oral Solution and consult your doctor if you experience severe diarrhoea.
Cleaning your colon will allow your doctor to see more clearly inside your colon during a colonoscopy.
This medication is only available with a doctor's prescription. Pegalup Oral Solution is used to cleanse the colon (bowel) before a colonoscopy. It should be taken only if advised by the doctor.
Pegalup Oral Solution is not recommended for patients with inflammatory bowel disease and intestinal obstruction disorders. Please inform your doctor before taking Pegalup Oral Solution if you have any liver disorders. Your doctor will only provide a prescription if the benefits outweigh the risks.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - PEG0055

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