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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Milical-OD3 Tablet is used to treat low blood calcium levels. It effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). It can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, it is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions. It contains Calcium orotate and Cholecalciferol (Vitamin D3), which provides essential nutrients to maintain bone formation and maintenance. Also, it raises Vitamin D levels and thereby increases calcium levels in the blood. It may cause side effects such as constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache.
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Manufacturer/Marketer

Glenmark Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

About Milical-OD3 Tablet

Milical-OD3 Tablet belongs to the class of 'dietary supplements primarily used to treat low blood calcium levels. Milical-OD3 Tablet effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Milical-OD3 Tablet can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Milical-OD3 Tablet is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Milical-OD3 Tablet consists of two medicines: Calcium orotate (mineral) and Cholecalciferol (Vitamin D3). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Cholecalciferol, also known as Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.

Milical-OD3 Tablet should be taken in the dose and duration as advised by your doctor. Depending on your medical condition, you are advised to take Milical-OD3 Tablet for as long as your doctor has prescribed it for you. In some cases, Milical-OD3 Tablet can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Milical-OD3 Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Milical-OD3 Tablet or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Milical-OD3 Tablet . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Milical-OD3 Tablet may pass into the breast milk; hence breastfeeding mothers need to seek medical advice before starting Milical-OD3 Tablet . Please tell your doctor if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Brief your medical history if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance.

Uses of Milical-OD3 Tablet

Treatment of Osteoporosis, Osteomalacia (Rickets), Calcium deficiency, Tetany, Hypoparathyroidism.

Medicinal Benefits

Milical-OD3 Tablet is a combination of two drugs, namely; Calcium orotate (mineral), Cholecalciferol (Vitamin D3), used to treat low blood calcium levels and various associated conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels). Calcium orotate is a mineral that prevents or treats calcium deficiency. It helps to maintain bone and teeth health. It is the only type of calcium penetrating the cell membrane and delivering maximum health benefits to cellular processes. Cholecalciferol, also known as Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Milical-OD3 Tablet

  • Constipation
  • Stomach upset
  • Nausea/vomiting
  • Loss of appetite
  • Excessive thirst
  • Mood changes
  • Bone/muscle pain
  • Fast or pounding heartbeat
  • Headache

Drug Warnings

If you are known to be allergic to Milical-OD3 Tablet or any other medicines, please tell your doctor. Milical-OD3 Tablet is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor before taking Milical-OD3 Tablet if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance. If you are pregnant or planning to become pregnant, it is advised to inform your doctor before using Milical-OD3 Tablet . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Cholecalciferol (vitamin D3) in higher doses may harm the fetus. Milical-OD3 Tablet may pass into the breast milk; hence consult your doctor before taking Milical-OD3 Tablet if you are a breastfeeding mother. Milical-OD3 Tablet should be used with caution in children and only if prescribed by a doctor. Cholecalciferol in Milical-OD3 Tablet can affect growth in children. Inform your doctor if your child is not growing normally while using the Milical-OD3 Tablet . Milical-OD3 Tablet contains aspartame (phenylalanine); hence caution should be taken to have an intolerance to sugars, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

Drug Interactions

Drug-Drug Interactions: Milical-OD3 Tablet may interact with calcium supplements (ergocalciferol, cholecalciferol), drugs treating bone loss (alendronate), anticonvulsants (carbamazepine, phenobarbital, phenytoin, primidone), diuretics (bendroflumethiazide, chlortalidone, indapamide), a drug used to treat heart disease (digoxin), medicines to treat tuberculosis (rifampicin, isoniazid), antacids (magnesium hydroxide), steroid medicines (hydrocortisone, prednisolone, dexamethasone), central nervous system stimulants (dextroamphetamine, amphetamine), anti-depressants (duloxetine), anti-ulcer drugs (ranitidine), painkillers (aspirin), anti-clotting drugs (anisindione, dicumarol, warfarin), drugs treating high cholesterol levels (cholestyramine, colesevelam, colestipol), and drugs that treat high blood phosphorus levels (sevelamer), antibiotics (tetracycline, doxycycline, minocycline), quinolone antibiotics (ciprofloxacin, levofloxacin), weight-loss drugs (orlistat).

Drug-Food Interactions: Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.

Drug-Disease Interactions: Milical-OD3 Tablet is contraindicated in hypercalcemia (high calcium level in blood), hypervitaminosis D (high vitamin D level in the body), Vitamin D toxicity, malabsorption syndrome, heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of tiny collections of inflammatory cells (granulomas) in any part of your body), Crohn's disease, Whipple's disease (a bacterial infection that most often affects joints and digestive system), achlorhydria (absence of stomach acid), low levels of bile, and phosphate imbalance.

Drug-Drug Interactions Checker List

  • ERGOCALCIFEROL
  • CALCITRIOL
  • ALENDRONATE SODIUM
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • BENDROFLUMETHIAZIDE
  • CHLORTALIDONE
  • INDAPAMIDE
  • DIGOXIN
  • RIFAMPICIN
  • ISONIAZID
  • MAGNESIUM HYDROXIDE
  • HYDROCORTISONE
  • PREDNISOLONE
  • DEXAMETHASONE
  • DEXTROAMPHETAMINE
  • AMPHETAMINE
  • DULOXETINE
  • RANITIDINE
  • ASPIRIN
  • ANISINDIONE
  • DICUMAROL
  • WARFARIN
  • CHOLESTYRAMINE
  • COLESEVELAM
  • COLESTIPOL
  • SEVELAMER
  • TETRACYCLINE
  • DOXYCYCLINE
  • MINOCYCLINE
  • CIPROFLOXACIN
  • LEVOFLOXACIN
  • ORLISTAT

Habit Forming

No

Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
  • Snack on calcium-rich nuts like Brazil nuts or almonds. 
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Special Advise

  • Low phosphate diet is recommended to control serum phosphorus levels in patients undergoing dialysis. 
  • Clinical monitoring of serum electrolyte concentrations and cardiac function is recommended.

Disease/Condition Glossary

Osteoporosis: Osteoporosis is a bone disease that weakens and brittle bones by decreasing bone density. As bones become less dense, they weaken and are more likely to break. Breaking a bone is a serious complication of osteoporosis, especially in older patients. Women are much more likely to develop osteoporosis than men. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, and a bone that breaks much more easily than expected.

 

Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D. Adults can experience a similar condition known as osteomalacia. It causes bone pain, poor growth, and soft, weak bones that can lead to bone deformities.

Tetany: A disease condition due to low levels of calcium (hypocalcemia) in the body that causes cramps and spasms in the hands, feet, and larynx (voice box).

Hypoparathyroidism: It is a disease characterized by low levels of parathyroid hormone. This can cause low calcium levels and trigger tetany.

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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Milical-OD3 Tablet .

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Pregnancy

Caution

Milical-OD3 Tablet should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Milical-OD3 Tablet .

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Breast Feeding

Caution

Milical-OD3 Tablet should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Milical-OD3 Tablet .

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Driving

Caution

Milical-OD3 Tablet does not impact your ability to drive or operate machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Milical-OD3 Tablet . Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek a doctor's advice before starting Milical-OD3 Tablet if you have kidney diseases like kidney stones or undergoing dialysis. Calcitriol in Milical-OD3 Tablet increases inorganic phosphate levels in serum; hence caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Safe if prescribed

The doctor will prescribe the dosage of Milical-OD3 Tablet based on the child's age and weight.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - MIL0168

Author Details

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FAQs

Milical-OD3 Tablet is used to treat low blood calcium levels. It effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). It can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Milical-OD3 Tablet is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.
Milical-OD3 Tablet is a combination of two medicines: Calcium orotate (mineral) and Cholecalciferol (Vitamin D3). Cholecalciferol helps your body absorb Calcium Carbonate and supports the muscles needed to avoid falls. Calcium helps build and maintain bones. Collectively, Milical-OD3 Tablet used to treat osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels).
Milical-OD3 Tablet can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Milical-OD3 Tablet as a daily supplement if you have kidney problems or kidney stones history.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose, and follow your usual dosage.
Cholecalciferol in Milical-OD3 Tablet can increase inorganic phosphate levels in serum; hence it should be cautiously used in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition). It is advised to follow a low phosphate diet to control serum phosphorus levels in dialysis patients.
Milical-OD3 Tablet is used to increase low levels of calcium in the body. Hence it is not advised to use Milical-OD3 Tablet during hypercalcemia since it causes an overdose of calcium leading to kidney stones and other effects.

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