Me-5 Tablet is used to treat nutritional deficiencies due to various complications or long-term diseases. It is used to treat and prevent folate deficiency, anaemia (lack of red blood cells), vitamin B12 deficiency and neurological diseases such as peripheral neuropathy (nerve disorder) and seizures (fits).

Me-5 Tablet contains folic acid and methylcobalamin. Folic acid (vitamin B9) replenishes the deficient folic acid in the body. It helps in the production of healthy red blood cells and DNA. Methylcobalamin (vitamin B12) regulates body functions like cell growth, blood formation and protein synthesis. It also prevents nerve damage by forming a protective layer (myelin) around the nerves.

You should take this medicine as prescribed by your doctor. The common side-effects of Me-5 Tablet are diarrhoea, loss of appetite, upset stomach, nausea (feeling sick) and bloating. These side effects are mild and don’t require medical attention. However, inform your doctor if any of these side effects persist or get worse.

Do not take Me-5 Tablet if you are allergic to any of its contents. Before taking Me-5 Tablet , inform your doctor if you are taking any prescription, non-prescription medicines, herbal products or dietary supplements. Inform your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food), cancer, kidney dialysis, optic nerve damage, hypokalemia (low potassium levels in the blood) and stent in the heart. Inform your doctor if you are pregnant or breastfeeding.

Me-5 Tablet is a combination of two medicines: Folic acid (vitamin B9) and Methylcobalamin (vitamin B12).  Together, Me-5 Tablet is used as a 'vitamin or nutritional supplement' in the treatment of folate deficiency anaemia, vitamin B12 deficiency, alcoholic neuropathy, pernicious anaemia (red blood cells are not produced due to Vitamin B12 deficiency), diabetic neuropathy (nerve damage due to high blood sugar levels), seizures (fits) and multiple sclerosis (immune system disease affecting the brain).

• Diarrhea
• Headache
• Anorexia (loss of appetite)
• Upset stomach
• Nausea (feeling sick)
• Bloating

Before taking Me-5 Tablet , inform your doctor if you have diabetes, cancer, obesity, neural tube defects, kidney problems, hypokalemia (low levels of potassium), and optic nerve damage. Do not take antacids before or after 2 hours of taking Me-5 Tablet as they may interfere with the action of Me-5 Tablet . Do not consume excess alcohol while using Me-5 Tablet as it may interfere with the drug absorption in the body.

Drug-drug interactions: Me-5 Tablet may interact with an antibiotic (chloramphenicol), anticancer agent (methotrexate and fluorouracil), anti-gout medicine (colchicine), antacids (cimetidine, omeprazole, lansoprazole, and ranitidine), a medicine used to treat diabetes (metformin), a medicine used to treat inflammatory bowel conditions (sulfasalazine), a medicine used to reduce cholesterol (cholestyramine), and antiepileptic drugs (phenytoin and fosphenytoin).

Drug-food interactions: No interactions found.

Drug-disease interactions: Me-5 Tablet should be used with caution in patients with malabsorption syndrome (difficulty absorbing nutrition from food), cancer, neural tube defects, kidney dialysis, optic nerve damage, diabetes, obesity, hypokalemia (low potassium levels in the blood) and stent in the heart.

• CHLORAMPHENICOL
• METHOTREXATE
• FLUOROURACIL
• COLCHICINE
• CIMETIDINE
• OMEPRAZOLE
• LANSOPRAZOLE
• RANITIDINE
• METFORMIN
• SULFASALAZINE
• CHOLESTYRAMINE
• PHENYTOIN
• FOSPHENYTOIN

• Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, and salmon, shellfish, oysters, clams, dark green vegetables, such as spinach and kale, beets, avocados, and potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
• Include fruits like citrus, banana, and watermelon in your diet.
• Avoid smoking and alcohol consumption.
• Exercise regularly, and maintain a healthy lifestyle. Avoid excess fatty foods.

• Serum levels of Cyanocobalamin present in Me-5 Tablet may be lowered by use of oral contraceptives.
• For pernicious anaemia,  the blood picture must be examined regularly.

Folic acid deficiency: It is the lack of vitamin B9 or folic acid in the body. Folic acid is essential for the formation of red blood cells. Symptoms of folic acid deficiency include mouth sores and fatigue. 

Vitamin B12 deficiency: When your body doesn't have adequate mineral levels, vitamin B12 and low haemoglobin are required for red blood cell formation. Signs and symptoms of low vitamin B12 include fatigue, breathlessness, numbness, poor balance and memory trouble.