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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MACROGOL SACHET is used to treat constipation. It works by drawing water into the intestine; this softens the stools making it easier to pass. In some cases, this medicine may cause side effects such as stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About MACROGOL SACHET

MACROGOL SACHET belongs to a class of drugs called laxatives used to treat constipation. Constipation refers to infrequent bowel movements in which the stools are often dry, painful, and hard to pass.

MACROGOL SACHET is a combination of four drugs, namely Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, MACROGOL SACHET helps in relieving constipation.

Take MACROGOL SACHET as advised by your doctor. In some cases, you may experience stomach pain, indigestion, mild diarrhoea, nausea, or vomiting. Most of these side effects of MACROGOL SACHET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to MACROGOL SACHET or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking MACROGOL SACHET. MACROGOL SACHET is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking MACROGOL SACHET. Drink plenty of fluids while taking MACROGOL SACHET. Do not take MACROGOL SACHET in more than the recommended doses.

Uses of MACROGOL SACHET

Treatment of Constipation

Directions for Use

Oral solution: Dilute it with water as advised by your doctor. Take it by mouth using the measuring cup provided with the pack. Shake the bottle well before each use.Sachet: Dissolve the contents of sachet in water as advised by the doctor. Drink it.

Medicinal Benefits

MACROGOL SACHET contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Also, it works by cleaning stool from the gastrointestinal tract. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, MACROGOL SACHET helps in comfortable bowel movement and provides relief from constipation.

How MACROGOL SACHET Works

MACROGOL SACHET is a combination of four drugs, namely Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools, making them easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, MACROGOL SACHET helps in relieving constipation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MACROGOL SACHET

  • Stomach pain
  • Indigestion
  • Mild diarrhoea
  • Nausea
  • Vomiting

What if I have taken an overdose of MACROGOL SACHET

Take MACROGOL SACHET only as advised by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to MACROGOL SACHET or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking MACROGOL SACHET. MACROGOL SACHET is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking MACROGOL SACHET. Drink plenty of fluids while taking MACROGOL SACHET. Do not take MACROGOL SACHET in more than the recommended doses. Discard MACROGOL SACHET after 30 days of first opening the bottle. Do not freeze or refrigerate MACROGOL SACHET.

Drug-Drug Interactions

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Potassium chlorideMeclizine
Critical
Potassium chlorideDisopyramide
Critical

Drug-Drug Interactions

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Potassium chlorideMeclizine
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Meclizine and Macrogol Sachet 14gm (oral form) together can increase the potassium levels in blood.

How to manage the interaction:
Taking Meclizine with Macrogol Sachet 14gm is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideDisopyramide
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Disopyramide and Macrogol Sachet 14gm together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Macrogol Sachet 14gm and Disopyramide is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideOrphenadrine (citrate)
Critical
How does the drug interact with Macrogol Sachet 14gm:
Combining Orphenadrine with Macrogol Sachet 14gm can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Orphenadrine (citrate) with Macrogol Sachet 14gm is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideDimenhydrinate
Critical
How does the drug interact with Macrogol Sachet 14gm:
Co-administration of Dimenhydrinate and Macrogol Sachet 14gm can increase the risk of stomach inflammation.

How to manage the interaction:
Co-administration of Dimenhydrinate with Macrogol Sachet 14gm is generally not recommended, as it can lead to an interaction, it can be taken when a doctor has prescribed it. However, if you experience severe stomach pain, sudden dizziness, vomiting (especially with blood), or dark stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideDexchlorpheniramine
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Dexchlorpheniramine and Macrogol Sachet 14gm can increase the risk of stomach inflammation.

How to manage the interaction:
Taking Dexchlorpheniramine with Macrogol Sachet 14gm (in tablet or capsule form) is avoided as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, lightheadedness, vomiting, or dark stools, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Potassium chlorideDoxepin
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Doxepin with Macrogol Sachet 14gm can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Doxepin with Macrogol Sachet 14gm is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideProcyclidine
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Procyclidine and Macrogol Sachet 14gm together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Procyclidine with Macrogol Sachet 14gm is not recommended, but it can be taken together if advised by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideClemastine
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Clemastine and Macrogol Sachet 14gm(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Clemastine with Macrogol Sachet 14gm is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideCyproheptadine
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Cyproheptadine with Macrogol Sachet 14gm can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Cyproheptadine with Macrogol Sachet 14gm is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop any medication without talking to a doctor.
Potassium chlorideDarifenacin
Critical
How does the drug interact with Macrogol Sachet 14gm:
Taking Darifenacin with Macrogol Sachet 14gm(oral capsule or tablet) can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darifenacin with Macrogol Sachet 14gm(oral capsule or tablet) is not recommended, as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medications without doctor's advise.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try maintaining a balanced diet, which includes fresh fruits and vegetables.
  • Stay hydrated, and drink enough water and fluids.
  • Exercise regularly, and stay fit.
  • Get enough sleep.
  • Eat food rich in fibre, such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados).

Habit Forming

No

Therapeutic Class

LAXATIVES

MACROGOL SACHET Substitute

Substitutes safety advice
  • Movicol Sachet 13.81 gm

    by Others

    4.75per tablet
  • Movicol Orange Liquid 200 ml

    by AYUR

    1.65per tablet
  • Glypo Oral Solution 200 ml

    by Others

    1.54per tablet
  • Pegclear Sugar Free Oral Solution 200 ml

    by Others

    1.84per tablet
  • Pegmed Orange Flavour Liquid 200 ml

    by Others

    1.48per tablet
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Alcohol

Caution

Interaction of alcohol with MACROGOL SACHET is unknown. Please consult a doctor before consuming alcohol while using MACROGOL SACHET.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. MACROGOL SACHET is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. MACROGOL SACHET is given to breastfeeding mothers only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe

MACROGOL SACHET usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take MACROGOL SACHET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take MACROGOL SACHET with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

MACROGOL SACHET is not recommended for children below 12 years of age as the safety and effectiveness were not established.

FAQs

MACROGOL SACHET belongs to a class of drugs called laxatives used to treat constipation.

MACROGOL SACHET contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools making it easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, MACROGOL SACHET helps in relieving constipation.

MACROGOL SACHET may cause mild diarrhoea as a side effect in the beginning of the treatment. It usually gets better by reducing the amount of MACROGOL SACHET intake. However, if the condition persists or worsens, please consult a doctor.

You are not recommended to take MACROGOL SACHET with anticonvulsants as it may reduce the effectiveness of anticonvulsants (medicines for epilepsy). However, please consult your doctor before taking MACROGOL SACHET with other medicines.

You are recommended to avoid foods that are high in fat and low in fiber such as ice cream, red meat, frozen meals, potato chips, cheese, hot dogs and hamburgers.

You are not recommended to take more than the advised dose of MACROGOL SACHET as it may cause excessive diarrhoea that might lead to dehydration. If you have diarrhoea, stop taking MACROGOL SACHET and drink plenty of fluids to avoid dehydration. However, if the condition persists or worsens, please consult a doctor.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - MAC0064

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