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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:35 PM IST
Frifel 10mg Syrup is used to treat constipation. It is also used to treat hepatic encephalopathy. It contains Lactulose, which works by absorbing water from the body and into the bowel. This softens stools and makes it easier to pass. Besides this, it also reduces the amount of ammonia in the blood of patients with liver disease by drawing ammonia from the blood into the colon, thereby facilitating the removal of toxins from the body. In some cases, you may experience certain common side effects such as diarrhoea, flatulence (wind), abdominal pain, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

LACTULOSE-10MG

Consume Type

ORAL

Return Policy

Not Returnable

About Frifel 10mg Syrup

Frifel 10mg Syrup belongs to the group of medicines called laxatives used to treat constipation. Frifel 10mg Syrup is also used to treat hepatic encephalopathy. Constipation refers to infrequent bowel movements in which the stools are often dry, painful and hard to pass. Hepatic encephalopathy is a liver disease which causes the accumulation of toxic substances in the bloodstream which are normally removed by the liver.

Frifel 10mg Syrup contains 'lactulose' which works by absorbing water from the body and into the bowel. This softens stools and makes it easier to pass. Besides this, it also reduces the amount of ammonia in the blood of patients with liver disease by drawing ammonia from the blood into the colon, thereby facilitating the removal of toxins from the body.

You are advised to take Frifel 10mg Syrup for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as diarrhoea, flatulence (wind), abdominal pain, nausea, and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Drink plenty of fluids (at least 6-8 glasses) while taking Frifel 10mg Syrup. Consult your doctor before taking Frifel 10mg Syrup if you are pregnant or breastfeeding. Frifel 10mg Syrup should be given to children only if prescribed by a child specialist. Do not take Frifel 10mg Syrup if you have galactosaemia (galactose indigestion disorder). Inform your doctor if you have diabetes, or if you are due to undergo a colonoscopy. Chronic use of unadjusted doses or misuse of Frifel 10mg Syrup may cause diarrhoea and electrolyte imbalance, therefore take it only as advised by the doctor.

Uses of Frifel 10mg Syrup

Treatment of Constipation, Hepatic encephalopathy

Medicinal Benefits

Frifel 10mg Syrup belongs to a group of medicines known as laxatives used to treat constipation. It works by drawing water into the bowel and makes the stool softer and easier to pass, thereby providing relief from constipation. Frifel 10mg Syrup helps in normalizing bowel movements. Frifel 10mg Syrup also helps in the growth of good gut bacteria which help in proper digestion. Frifel 10mg Syrup is also used to treat hepatic encephalopathy. It works by reducing the amount of ammonia in the blood of patients with liver disease by drawing ammonia from the blood into the colon, thereby facilitating the removal of toxins from the body.

Directions for Use

Oral Solution/Syrup: Shake the bottle well and take the prescribed dose/quantity by mouth using the measuring cup provided by the pack. You can also mix it with water or fruit juice.Powder/granules- Dissolve the contents in water and consume it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Frifel 10mg Syrup

  • Diarrhoea
  • Flatulence (wind)
  • Abdominal pain
  • Nausea
  • Vomiting

Drug Warnings

Do not take Frifel 10mg Syrup if you are allergic to any of its contents, if you have galactosaemia (galactose indigestion disorder), galactose or fructose intolerance, glucose-galactose malabsorption, Lapp lactase deficiency, intestinal blockage, or digestive perforation. Inform your doctor if you are unable to digest lactose/lactose intolerant, have diabetes, irritable bowel syndrome, or if you are due to undergo a colonoscopy. Consult your doctor before taking Frifel 10mg Syrup if you are pregnant or breastfeeding. Chronic use of unadjusted doses or misuse of Frifel 10mg Syrup may cause diarrhoea and electrolyte imbalance, therefore take it only as advised by the doctor.

Drug Interactions

Drug-Drug Interactions: Frifel 10mg Syrup may have interaction with diuretic (furosemide), laxatives (docusate, polyethylene glycol), anti-emetic (ondansetron), and anti-psychotic (quetiapine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Frifel 10mg Syrup may have interactions with conditions such as intestinal obstruction disorder, and galactosemia (galactose indigestion disorder).

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • DOCUSATE
  • POLYETHYLENE GLYCOL
  • QUETIAPINE
  • ONDANSETRON

Habit Forming

No

Diet & Lifestyle Advise

  • Try maintaining a balanced diet which includes fresh fruits and vegetables.
  • Stay hydrated, drink enough water and fluids.
  • Exercise regularly, and stay fit.
  • Get enough sleep.
  • Trying making time to empty your bowels whenever the body tells you to.
  • Eat food rich in fibre such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs) and vegetables (broccoli, spinach, sweet potatoes, avocados).

Special Advise

If you are undergoing any surgery or tests on your rectum or colon, inform the doctor that you are taking Frifel 10mg Syrup.

Disease/Condition Glossary

Constipation: It refers to infrequent bowel movements. The stools are often dry, painful and hard to pass. Constipation is a medical condition in which the person has fewer than three bowel movements in a week. However, bowel patterns may vary from person to person. Symptoms include bloating, abdominal pain, and feeling as if the bowel movement is incomplete. Constipation occurs when the normal muscle contractions in the large intestine slow down, which causes the incomplete elimination of the bowel from the body. Constipation could be associated with a sudden change of diet, a diet with less fibre, not drinking enough liquids, and lack of exercise.

Hepatic encephalopathy: It is a liver/hepatic disease in which the liver does not remove the toxins from the body, which leads to loss of brain function. Hepatic encephalopathy causes confusion, tremor, decreased consciousness and coma.

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Alcohol

Caution

It is not known if alcohol consumption affects Frifel 10mg Syrup. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Please consult your doctor before taking Frifel 10mg Syrup if you are pregnant; your doctor will prescribe Frifel 10mg Syrup if the benefits outweigh the risks. Frifel 10mg Syrup should be taken with caution during the first 3 months of pregnancy.

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Breast Feeding

Caution

Please consult your doctor before taking Frifel 10mg Syrup if you are breastfeeding; your doctor will prescribe Frifel 10mg Syrup if the benefits outweigh the risks.

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Driving

Safe if prescribed

Frifel 10mg Syrup usually does not affect your ability to drive.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Frifel 10mg Syrup can be given to children if prescribed by a doctor.

Country of origin

India
Other Info - FR42287

Author Details

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FAQs

Frifel 10mg Syrup is used for the treatment of constipation and hepatic encephalopathy.
Frifel 10mg Syrup works by drawing water into the bowel and makes the stool softer and easier to pass, thereby providing relief from constipation.
Frifel 10mg Syrup is used to treat hepatic encephalopathy in adults. Hepatic encephalopathy is a liver disease in which the liver does not remove the toxins from the body, which leads to loss of brain function.
Diarrhea might occur if Frifel 10mg Syrup is taken in larger doses. Drink lots of fluids if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Do not take Frifel 10mg Syrup for longer durations unless prescribed by the doctor. Taking Frifel 10mg Syrup for longer durations might cause dehydration, an imbalance of electrolytes in the body which can affect the tightness of muscles in the intestine. If your bowel movement is irregular even after taking Frifel 10mg Syrup for a week, consult your doctor.
Frifel 10mg Syrup contains lactulose, a synthetic sugar. In normal doses, it might not affect your blood glucose levels. However, consult your doctor before taking Frifel 10mg Syrup if you are diabetic.
Frifel 10mg Syrup starts working within 1-2 days. Consult the doctor if constipation does not improve even after 4-5 days of taking Frifel 10mg Syrup.
Yes, Frifel 10mg Syrup is an osmotic laxative that softens the stools and treats constipation.
Side effects of Frifel 10mg Syrup include diarrhoea, flatulence (wind), abdominal pain, nausea, and vomiting. Talk to your doctor if you experience these side effects persistently.
You are advised to take Frifel 10mg Syrup for the duration prescribed by the doctor. Do not exceed the recommended duration.
Frifel 10mg Syrup should not be given to people who are allergic to any of its contents, have galactosaemia (galactose indigestion disorder), galactose or fructose intolerance, glucose-galactose malabsorption, Lapp lactase deficiency, intestinal blockage, or digestive perforation.
Other laxatives can be taken along with Frifel 10mg Syrup only if prescribed by the doctor as there could be an increased risk of side effects.
Avoid exceeding the recommended dose of Frifel 10mg Syrup as it may cause diarrhoea, abdominal cramps and dehydration. Drink enough fluids and consult the doctor if you experience these symptoms.

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