Dolfre Gel is used to relieve acute musculoskeletal pain and pain of osteoarthritis of joints. It reduces pain, swelling, and joint stiffness, thereby improving your ability to move and flex the joint.

Dolfre Gel contains Diclofenac and Methyl salicylate (as a pain killer), Linseed oil (as an anti-inflammatory), and Menthol (as a cooling agent). Dolfre Gel works by first cooling the skin and then warming it up, which interferes with the pain signal transmission through nerves. Together Dolfre Gel works by blocking the release of chemical messengers that causes pain and inflammation with redness and swelling.

Dolfre Gel should only be used if advised by your doctor. Dolfre Gel should be used for skin only, and accidentally if it gets into your eye, mouth, or nose, rinse with water. Dolfre Gel should be applied to the affected area with a piece of clean cotton wool or gauze swab. Dolfre Gel should not be applied more than the recommended dose to avoid unpleasant side effects. Some common side effects of Dolfre Gel are burning, itching, redness, stinging, and dryness on your skin in the place where Dolfre Gel is applied. These side effects are usually mild and short-lived. However, if the side effects are persistent, reach out to your doctor.

Dolfre Gel is contraindicated in children below two years of age. Besides this, caution must be exercised when older children (2-12 years) are treated. Children affected with viral flu, chickenpox, or viral fever should avoid using Dolfre Gel as it contains methyl salicylate may induce Reyes Syndrome (swelling in the liver and brain).

Dolfre Gel contains Diclofenac and Methyl salicylate (as a pain killer), Linseed oil (as an anti-inflammatory), and Menthol (as a cooling agent). Dolfre Gel works by first cooling the skin and warming it up, interfering with the pain signal transmission through nerves. Together Dolfre Gel works by blocking the release of chemical messengers that causes pain and inflammation with redness and swelling.

• Skin irritation
• Contact dermatitis
• Rash
• Itching
• Redness
• Swelling
• Burning or stinging sensation

Before using Dolfre Gel, tell your doctor if you are allergic to Dolfre Gel other pain killers (like ibuprofen, naproxen, celecoxib) or if you have any other allergies. Use of Dolfre Gel is contraindicated in the people who have asthma, liver disease, kidney disease, stomach/intestine problems (bleeding, ulcers, Crohn's disease), cardiovascular diseases (heart attack, high blood pressure, stroke), swelling (oedema, fluid retention), blood disorders (such as anaemia), bleeding/clotting problems. Dolfre Gel should not be given to children less than 2 years of age. The use of Dolfre Gel should be done with caution in the elderly as they have a high risk of kidney damage and gastrointestinal bleeding.

Drug-Drug Interaction: Dolfre Gel may interact with ACE inhibitors (captopril, lisinopril), angiotensin II receptor blockers (losartan, valsartan), cidofovir, corticosteroids (dexamethasone, prednisone), lithium, methotrexate, diuretics (furosemide). Dolfre Gel may increase the risk of bleeding when used with other drugs that also may cause bleeding.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: No interactions found.

• CAPTOPRIL
• LISINOPRIL
• LOSARTAN
• VALSARTAN
• CIDOFOVIR
• DEXAMETHASONE
• PREDNISONE
• LITHIUM
• METHOTREXATE
• FUROSEMIDE

Caution should be exercised, it is advisable to consult a doctor before using it. “Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke.”

Osteoarthritis is a long term musculoskeletal joint disorder that causes damage to the cartilage and surrounding tissues characterized by pain, swelling, stiffness, and loss of function. The joint disorder becomes common with ageing and wear and tear of joints. Pain, swelling, bony overgrowth, and stiffness can be observed that follows inactivity and disappears within 30 minutes when the joint is moved. The diagnosis of osteoarthritis is based on symptoms and X-rays of the affected joints. Its treatment includes exercises, an analgesic that reduce pain and improve function, and finally joint replacement or other surgery like total knee replacement.