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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Combisafe-D Tablet is used to treat neuropathic pain and nutritional deficiencies. It helps rejuvenate and protect damaged nerve cells, lowers oxidative stress, and provides essential nutrients. In some cases, this medicine may cause side effects such as stomach upset, diarrhoea, nausea, and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Synonym :

ALPHA LIPOIC ACID+CHOLECALCIFEROL+FOLIC ACID+MECOBALAMIN+PYRIDOXINE

Manufacturer/Marketer :

Alniche Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Combisafe-D Tablet

Combisafe-D Tablet contains nutritional supplements used to treat neuropathic pain associated with diabetic neuropathy and nutritional deficiencies. Combisafe-D Tablet might help enhance blood calcium levels, fasten metabolism, facilitate the conversion of glucose into energy, helps improve the body’s oxidative stores, and develop healthy red blood cells. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. A nutritional deficiency occurs when the body does not absorb or get enough nutrients from food.
 
The Combisafe-D Tablet consists of five supplements: Alpha-lipoic acid, Methylcobalamin, Cholecalciferol, Folic acid, and Pyridoxine. Methylcobalamin and pyridoxine help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant that prevents oxidative stress, thereby helps in providing a protective effect on the nerve tissues and brain. Cholecalciferol helps in resolving neuropathic symptoms and improves balance. Folic acid helps in providing essential nutrients. Together, Combisafe-D Tablet helps treat diabetic neuropathy and nutritional deficiencies.
 
Take Combisafe-D Tablet as recommended. You are advised to take Combisafe-D Tablet for as long as your doctor has suggested it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as stomach upset, diarrhea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
It is unknown if alcohol interacts with Combisafe-D Tablet , so please consult a doctor if you have any concerns. Consult your doctor before taking Combisafe-D Tablet if you are pregnant or breastfeeding. Limited information is available regarding the usage of Combisafe-D Tablet in children, so please consult a doctor. Drive only if you are alert as it is unknown if Combisafe-D Tablet affects your ability to drive. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Combisafe-D Tablet

Treatment of Diabetic neuropathy, nutritional deficiency.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

The Combisafe-D Tablet consists of five supplements: Alpha-lipoic acid, Methylcobalamin, Cholecalciferol, Folic acid, and Pyridoxine. Combisafe-D Tablet is used to treat neuropathic pain and nutritional deficiencies. Methylcobalamin and pyridoxine help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Cholecalciferol helps in resolving neuropathic symptoms and improves balance. Alpha-lipoic acid is an antioxidant that prevents oxidative stress, thereby helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Combisafe-D Tablet helps in providing relief from neuropathic pain.

How Combisafe-D Tablet Works

The Combisafe-D Tablet consists of five supplements: Alpha-lipoic acid, Methylcobalamin, Cholecalciferol, Folic acid, and Pyridoxine. Methylcobalamin and pyridoxine help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant that prevents oxidative stress, thereby helps in providing a protective effect on the nerve tissues and brain. Cholecalciferol helps in resolving neuropathic symptoms and improves balance. Folic acid helps in providing essential nutrients. Together, Combisafe-D Tablet helps treat diabetic neuropathy and nutritional deficiencies.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Combisafe-D Tablet

  • Diarrhoea
  • Stomach upset
  • Nausea
  • Vomiting

What if I have taken an overdose of Combisafe-D Tablet

Take Combisafe-D Tablet only as advised by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Combisafe-D Tablet if you are allergic to any of its contents. Inform your doctor before taking Combisafe-D Tablet if you have diabetes, thyroid problems, epilepsy, anaemia, infection, kidney or liver problems. Consult your doctor before taking Combisafe-D Tablet if you are pregnant or breastfeeding. Limited information is available regarding the usage of Combisafe-D Tablet in children, so please consult a doctor. Keep your doctor informed about your health condition and the medicines you are taking to rule out any interactions.

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
ParacetamolOxazepam
Severe

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of Atenolol with Combisafe-D Tablet 10's could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Combisafe-D Tablet 10's, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of Combisafe-D Tablet 10's may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Combisafe-D Tablet 10's, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of Combisafe-D Tablet 10's and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet 10's and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of Mipomersen with Combisafe-D Tablet 10's may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Combisafe-D Tablet 10's and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of Teriflunomide with Combisafe-D Tablet 10's may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Combisafe-D Tablet 10's with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of Lomitapide and Combisafe-D Tablet 10's may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet 10's and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetamine
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of ketamine and Combisafe-D Tablet 10's may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Combisafe-D Tablet 10's together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of Combisafe-D Tablet 10's and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet 10's and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Combisafe-D Tablet 10's:
Co-administration of Combisafe-D Tablet 10's and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Combisafe-D Tablet 10's and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well, get plenty of sleep.

  • Try taking a warm bath as it can be soothing.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT
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Alcohol

Caution

It is not known if alcohol interacts with Combisafe-D Tablet , so please consult a doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will advise only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Combisafe-D Tablet ; your doctor will decide whether Combisafe-D Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

It is unknown if Combisafe-D Tablet affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Limited information is available regarding the usage of Combisafe-D Tablet in patients with liver problems. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Limited information is available regarding the usage of Combisafe-D Tablet in patients with kidney problems. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Limited information is available regarding the usage of Combisafe-D Tablet in children, so please consult a doctor.

FAQs

Combisafe-D Tablet contains nutritional supplements used to treat neuropathic pain associated with diabetic neuropathy and nutritional deficiencies.
Combisafe-D Tablet is used to treat neuropathic pain associated with diabetic neuropathy. Besides this, it can also help to treat nutritional deficiency.
Combisafe-D Tablet consists of Methylcobalamin, Cholecalciferol, Alpha lipoic acid, Folic acid, and Pyridoxine. Mecobalamin and pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Cholecalciferol helps in resolving neuropathic symptoms and improves balance. Together, Combisafe-D Tablet helps in providing relief from neuropathic pain.
To treat your condition effectually, continue taking Combisafe-D Tablet for as long as recommended. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Combisafe-D Tablet .
Combisafe-D Tablet may be used to treat nutritional deficiencies, helps enhance blood calcium levels, fastens metabolism, facilitates the conversion of glucose into energy, helps improve the body’s oxidative stores, and development of healthy red blood cells.
Diarrhoea could be a side-effect of Combisafe-D Tablet . Eat non-spicy meals and drink plenty of fluids if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.
Combisafe-D Tablet may be used as an adjunct therapy for diabetic patients suffering from diabetic neuropathy. However, you are advised to consult a doctor before taking Combisafe-D Tablet if you are diabetic. Combisafe-D Tablet contains alpha-lipoic acid, which might cause low blood sugar. Regularly monitor blood glucose levels while taking Combisafe-D Tablet .

Country of origin

India

Manufacturer/Marketer address

S-14, 1St Floor, Janta Market, Rajouri Garden, New Delhi, 110 027
Other Info - COM0669

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