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Written By ,
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 26, 2024 | 7:06 PM IST
Com-D3 400IU Drops is a combination medicine primarily used to treat nutritional deficiencies, low calcium levels (hypocalcaemia), osteoporosis, osteomalacia (Rickets), and vitamin D deficiency. This medicine works by increasing the calcium and vitamin D levels in the body and regulates bodily functions, thus providing essential nutrients necessary for bone formation and maintenance. Common side effects include constipation, nausea, vomiting, and stomach upset.
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Synonym

CHOLECALCIFEROL

Composition

VITAMIN D3-400IU

Manufacturer/Marketer

Comed Chemicals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

About Com-D3 400IU Drops

Com-D3 400IU Drops is used to treat low blood calcium levels. Com-D3 400IU Drops effectively treats various conditions in the body like Vitamin D deficiency, osteoporosis (weak and brittle bones), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), latent tetany (a muscle disease with low blood calcium levels) and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). Vitamin D deficiency occurs when your body has low Vitamin D levels and is caused due to inadequate nutrition, intestinal malabsorption or lack of sunlight exposure.

Com-D3 400IU Drops contains 'Vitamin-D3' (Cholecalciferol). It helps maintain blood calcium and phosphorus levels and the mineralization of bone. It is used to treat and prevent bone disorders, such as rickets and osteomalacia. It aids in calcium absorption, enabling bone growth and repair. It further prevents cartilage degeneration.

Your doctor will decide the dosage based on your medical condition. Com-D3 400IU Drops is likely safe to use. In some cases, it may cause side effects like constipation, vomiting, and nausea. These side effects do not require medical attention and gradually resolve over time. If these side effects persist, please consult your doctor immediately.

If you take any medicines or supplements, inform your doctor before starting Com-D3 400IU Drops. If you are allergic to Com-D3 400IU Drops or any other medicines, inform your doctor before starting Com-D3 400IU Drops. Pregnant or breastfeeding women should consult their doctor before taking Com-D3 400IU Drops. This supplement does not interfere with your driving ability. Limit alcohol intake while using Com-D3 400IU Drops. This supplement is recommended for children when advised by a doctor.

Uses of Com-D3 400IU Drops

Treatment of Osteoporosis, Osteomalacia (Rickets), Vitamin D deficiency, Hypoparathyroidism, and Latent tetany

Medicinal Benefits

Com-D3 400IU Drops contains Vitamin D3 (Cholecalciferol). It is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from food sources. It is a provitamin that is converted into a vitamin after intake.  It helps maintain blood calcium and phosphorus levels and the mineralization of bone. Com-D3 400IU Drops is also used in the treatment of familial hypophosphatemia (a group of rare inherited disorders characterized by impaired kidney conservation of phosphate and in some cases, altered vitamin D metabolism).

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew or break it.Chewable tablet: Take the chewable tablet by mouth. Chew it completely before swallowing.Sachet/Powder: Check the label for directions before use. Mix the recommended amount in water, stir well and drink immediately.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Com-D3 400IU Drops

  • Constipation
  • Nausea
  • Vomiting

Drug Warnings

Com-D3 400IU Drops should be used with caution in hypercalcemia, renal impairment, electrolyte imbalance, heart diseases, kidney stones and hypervitaminosis D. Tell your doctor if you are allergic to Com-D3 400IU Drops. Chewable tablets of Vitamin D3 may contain sugar or aspartame, hence caution should be taken in diabetes and phenylketonuria. Please check the product leaflet before consumption.  Pregnant or breastfeeding women should consult their doctor before taking Com-D3 400IU Drops. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Com-D3 400IU Drops is safe to use in children when advised by the doctor.

Drug Interactions

Drug-Drug Interaction: Com-D3 400IU Drops may interact with drugs treating high cholesterol levels (cholestyramine), anti-epileptic (carbamazepine, phenobarbital), antibiotics (doxycycline, neomycin, and chloramphenicol), drugs treating bone loss (alendronate), thyroid hormone (levothyroxine), diuretics (hydrochlorothiazide) and heart-related medicines (digoxin).

Drug-Food Interaction: Limit alcohol intake during the course to get the maximum benefits of Com-D3 400IU Drops.

Drug-Disease Interaction: Let your doctor know if you have hypercalcemia, hypervitaminosis D, malabsorption syndrome (difficulty absorbing nutrition from food), Vitamin D toxicity, heart/kidney/liver/blood vessel diseases, and kidney stones before using Com-D3 400IU Drops.

Drug-Drug Interactions Checker List

  • CHOLESTYRAMINE
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • DOXYCYCLINE
  • NEOMYCIN
  • CHLORAMPHENICOL
  • ALENDRONATE SODIUM
  • LEVOTHYROXINE
  • HYDROCHLOROTHIAZIDE
  • DIGOXIN

Habit Forming

No

Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese or milk-based custard in your diet.

  • Eat daily a serving of broccoli, cabbage, bok choy, spinach and other green leafy vegetables.

  • Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D–fortified milk.

  • Snack on calcium-rich nuts like Brazil nuts or almonds. 

  • Spend time under the sunlight for at least 30 minutes early in the morning.

  • Sprinkle sesame seeds over your food, vegetables and salads. Sesame seeds are high in calcium.

  • Avoid or reduce the intake of caffeine, soft drinks and alcohol that inhibit calcium absorption.

  • Replace the meat with tofu or tempeh for extra calcium in your food.

Special Advise

It is advised to timely monitor your Vitamin D levels through blood examination.

Disease/Condition Glossary

Vitamin D deficiency: When a person cannot get enough Vitamin D through food and exposure to sunlight, it leads to vitamin D deficiency. It often leads to thin, brittle, or misshapen bones. 

Osteoporosis: It is a bone disease that makes the bones weak and brittle by decreasing bone density. 

Tetany: A disease condition due to low calcium levels (hypocalcemia) in the body that causes cramps and spasms in the hands, feet, and larynx (voice box).

Osteomalacia/Rickets: A disease caused by softening and weakening of bones in children due to inadequate vitamin D. 

Hypoparathyroidism: It is a disease characterized by low levels of parathyroid hormone. This can cause low calcium levels and trigger tetany (muscle cramps, spasms, or tremors). 

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Alcohol

Caution

It is advisable to limit/avoid alcohol intake during the treatment. Please consult a doctor before consuming alcohol while using Com-D3 400IU Drops.

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Pregnancy

Consult your doctor

Inform your doctor if you are pregnant before taking Com-D3 400IU Drops.

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Breast Feeding

Consult your doctor

Please consult your doctor if you are a nursing mother before taking Com-D3 400IU Drops.

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Driving

Safe

Com-D3 400IU Drops usually does not interfere with your driving ability.

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Liver

Caution

Inform your doctor if you have any history of liver diseases before taking Com-D3 400IU Drops. Liver impairment can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek your doctor's advice before starting Com-D3 400IU Drops if you have kidney diseases like kidney stones or undergoing dialysis.

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Children

Consult your doctor

Com-D3 400IU Drops should be used in children only when advised by a doctor. Dose adjustment may be necessary.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, Sun Plaza-I, Nr. Vadsar Bridge, Gidc Road, Makarpura, Vadodara - 390 010
Other Info - COM0636

FAQs

Com-D3 400IU Drops is used to treat vitamin D deficiency. It effectively treats various conditions in the body like low calcium levels, osteoporosis (weak and brittle bones), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), latent tetany (a muscle disease with low blood calcium levels)Â and rickets or osteomalacia (softening or deforming of bones due to lack of calcium).
Com-D3 400IU Drops is a dietary supplement that consists of Vitamin D3 (Cholecalciferol). It helps maintain blood calcium and phosphorus levels and the mineralization of bone. When you don't get enough Vitamin D from food sources and sunlight exposure, Com-D3 400IU Drops helps replenish those low levels.
Com-D3 400IU Drops should be used with caution in conditions like hypercalcaemia (high calcium levels), hypervitaminosis D (high vitamin D levels), liver/kidney problems, heart diseases, phenylketonuria (increased phenylalanine levels in the blood), and diabetes.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Antacids usually do not interfere with the absorption of Com-D3 400IU Drops. However, it is advised to take Com-D3 400IU Drops two hours before or four hours after taking antacids.
Fatty fish (tuna, trout, salmon, and mackerel), fish liver oil, egg yolk, and beef liver are good sources of Vitamin D. Vitamin D-fortified foods like plant milk, dairy, juices, and breakfast cereals are also good sources of Vitamin D.
Not getting enough vitamin D through diet/food, limited exposure to sunlight, organs such as the liver or kidney not being able to convert vitamin D to its active form in the body, taking medicines which interfere with the absorption of vitamin D may cause deficiency of vitamin D.
People who are allergic to vitamin D, have hypervitaminosis D (high levels of vitamin D), hypercalcemia (high levels of calcium) or malabsorption syndrome should not take Com-D3 400IU Drops.
Taking too much of Com-D3 400IU Drops may cause overdose and hypervitaminosis D (high levels of vitamin D). The symptoms of overdose include loss of appetite, confusion, nausea, body pains, urinating more or less than usual, thirst, irregular heartbeats or stiffness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
The amount of Vitamin D3 needed depends on age. The average daily recommended amount as per NIH is Birth-12 months: 400IU1-13 years: 600IU14-18 years: 600IU19-70 years: 600IU71 years and older: 800IUPregnant and breastfeeding women: 600IU
Vitamin D deficiency may cause rickets (bones become soft, weak and deformed) in children and osteomalacia (a bone disorder that causes muscle weakness and bone pain) in adults.
Vitamin D is essential for various body functions. It maintains bone health by regulating the amount of calcium and phosphate in the body. Vitamin D supports muscle and nerve health and enhances immune system.
Yes, Com-D3 400IU Drops is a health supplement used to treat vitamin D deficiency.
It can be harmful if you take too much. Avoid exceeding the recommended dose and take it as advised by the doctor.
It is probably safe to use Com-D3 400IU Drops during pregnancy. However, consult a doctor if you are pregnant or planning for pregnancy.
Usually, vitamin D is to be taken once a week. How often you need to take Com-D3 400IU Drops depends on the dose and your condition. Please consult the doctor and take it as advised.
Com-D3 400IU Drops can be taken at night or in the morning.
Com-D3 400IU Drops strengthens bone, muscles, supports immune health, promotes heart health, enhances hair, regulates mood, and provides resistance to infections.
Com-D3 400IU Drops should be swallowed as a whole with water; do not crush or chew it.
Regular sun exposure is the natural way to get vitamin D. It is optimal to have sun exposure for 5 to 30 minutes a day, most days a week, without sunscreen. However, if you have low levels of vitamin D supplementation may be required.
Usually, vitamin D supplements require few weeks to enhance the levels of vitamin D in the body. To treat your condition effectively, keep taking Com-D3 400IU Drops for the recommended duration.
No, do not take Com-D3 400IU Drops if you are allergic to any of its ingredients.
Vitamin D improves bone health, controls infections, enhances immunity, lowers inflammation, and aids various body functions.
In some cases, it may cause side effects like constipation, vomiting, and nausea. These side effects do not require medical attention and gradually resolve over time. If these side effects persist, please consult your doctor immediately.
Other medications can be taken with Com-D3 400IU Drops if advised by the doctor. Let the doctor know if you are taking any other medicines particularly antibiotics, cholesterol-lowering medicines, anticonvulsants, thyroid medicines, and medicines used to treat bone loss.
Store Com-D3 400IU Drops at room temperature, in a dry place. Keep out of sight and reach of children.

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