Carmicide Paediatric Oral Liquid belongs to the class of medications called ‘Alkalinizing agents’ used to prevent gout, kidney stones, and treat metabolic acidosis in patients with kidney diseases. Gout is a type of arthritis in which uric acid crystals are deposited in the joints leading to severe pain, redness, and swelling in the joints. A kidney stone is a condition in which hard deposits are accumulated in the kidney forming stones. Metabolic acidosis is a condition in which excess acid is accumulated in the body due to kidney failure.

Carmicide Paediatric Oral Liquid is a combination of two medicines: Citric acid and Sodium citrate. Citric acid prevents the formation of deposits by binding with the salts, and it also breaks down the small deposits that are beginning to form. Sodium citrate is metabolized to sodium bicarbonate in the body. It is alkaline in nature and works by neutralizing the acids in the blood and urine, thereby preventing the accumulation of salts in the body.

 You should take this medicine as prescribed by your doctor. Carmicide Paediatric Oral Liquid may cause side-effects such as diarrhoea, upset stomach, nausea, and vomiting. These side-effects are mild and temporary. However, inform your doctor if any of these side-effects persist or get worsen.

Do not take Carmicide Paediatric Oral Liquid if you are allergic to Citric acid, Sodium citrate, or any other ingredients present in it. It should not be used in patients with severe kidney failure, severe heart damage, severe dehydration, heat cramps, Addison’s disease (an adrenal gland disorder), and hyperkalemia (high potassium levels in the blood). Before taking Carmicide Paediatric Oral Liquid , inform your doctor if you have hypertension (high blood pressure), heart attack history, oedema (fluid retention), urinary problems, or chronic diarrhoea. Inform your doctor if you are pregnant or breastfeeding.

Carmicide Paediatric Oral Liquid is a combination of two medicines: Citric acid and Sodium citrate. Citric acid prevents the formation of deposits by binding with the salts, and it also breaks down the small deposits that are beginning to form. Sodium citrate is metabolized to sodium bicarbonate in the body. It is alkaline in nature and work by neutralizing the acids in the blood and urine. Carmicide Paediatric Oral Liquid reduces the crystallization of stone-forming salts such as calcium oxalate (in kidney stones) and uric acid (in gout) effectively.

• Diarrhea
• Upset stomach
• Nausea
• Vomiting

Carmicide Paediatric Oral Liquid should be used with caution in patients with kidney disease, heart diseases, hypertension (high blood pressure), electrolyte imbalances, urination problems, toxaemia of pregnancy (high blood pressure during pregnancy), oedema (swelling), and chronic diarrhoea. Do not take antacids without consulting your doctor while using Carmicide Paediatric Oral Liquid as it may lead to electrolyte imbalances. Do not take food containing sodium bicarbonate (baking soda) or foods high in salt as they may worsen your condition. Stop using Carmicide Paediatric Oral Liquid and consult a doctor immediately if you notice muscle twitching, swelling, weakness, mood changes, weight gain, increased heart rate, black or tarry stools, severe diarrhoea, or convulsions (fits) while using Carmicide Paediatric Oral Liquid .

Drug-Drug Interactions: Carmicide Paediatric Oral Liquid should not be used with an antacid containing aluminium (aluminium hydroxide) as it may cause aluminium toxicity, other antacids, pain killer (aspirin), antipsychotic medication (lithium), a medication used to treat urinary tract infection (methenamine), and a medication used to treat arrhythmia (quinidine).

Drug-Food Interactions: Avoid foods containing sodium bicarbonate (baking soda) and high amounts of salt.

Drug-Disease Interactions: Carmicide Paediatric Oral Liquid should be avoided in patients with electrolyte imbalances, inflammatory bowel disease, intestinal blockage, severe dehydration, urination problems, heart failure and Addison’s disease (adrenal gland disorder).

• ALUMINIUM HYDROXIDE
• ASPIRIN
• LITHIUM
• QUINIDINE
• METHENAMINE

• Drink plenty of fluids.
• Limit consumption of spinach, wheat bran, nuts, beets and dairy products.
• Avoid high salt intake and foods containing baking soda.
• Do not take vitamin C and calcium supplements without your doctor’s advice.

• It is essential to follow a specific diet plan created by your nutritionist to control the health condition.
• Your doctor may advise you to take blood and urine tests while using Carmicide Paediatric Oral Liquid to examine your health condition and ensure that this medicine treats your condition.

Gout: It is a type of arthritis in which patients experience severe pain, redness, and swelling in joints. The most common affected area is the joint at the base of the big toe. Patients with gout may often experience acute attacks that result in sudden and severe pain. It occurs due to a condition called hyperuricemia (high uric acid levels in the body). The excess uric acid deposit and crystallize in the joints leading to pain and inflammation.

Kidney stones: It is a condition in which hard deposits occur in the kidney leading to stones. A kidney stone comprises mainly four types: calcium oxalate, uric acid, struvite and cystine. It is due to the increased level of uric acid in the body. As a result, uric acid crystals start depositing in the kidney, known as renal calculi/nephrolithiasis/urolithiasis.

Metabolic acidosis: It is a condition in which excess acid is accumulated in the body due to the kidney's inability to remove excess acid from the body. It can be of various types such as lactic acidosis (build-up of lactic acid), diabetic acidosis (build-up of ketone bodies), and hyperchloremic acidosis (build-up of sodium bicarbonate). It is mostly seen in patients with kidney impairment.