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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Calnef Plus Softgel Capsule is used to treat various conditions caused by low calcium levels in the body like Vitamin D deficiency, osteoporosis (weak and brittle bones), hypoparathyroidism (a condition in which parathyroid glands make low levels of calcium in the body), latent tetany (a muscle disease with low blood calcium levels), and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). It consists of calcium and calcitriol (vitamin D). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Calcitriol is a synthetic form of vitamin D that helps maintain blood calcium and phosphorus levels and mineralization of bone.

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Synonym :

CALCIUM CITRATE+CALCITRIOL

Manufacturer/Marketer :

Myren Life Science India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Calnef Plus Softgel Capsule

Calnef Plus Softgel Capsule belongs to the class of 'vitamins,' primarily used to treat various conditions caused by low calcium levels in the body like Vitamin D deficiency, osteoporosis (weak and brittle bones), hypoparathyroidism (a condition in which parathyroid glands make low levels of calcium in the body), latent tetany (a muscle disease with low blood calcium levels), and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). 

Calnef Plus Softgel Capsule consists of calcium and calcitriol (vitamin D). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Calcitriol is a synthetic form of vitamin D that helps maintain blood calcium and phosphorus levels and mineralization of bone.

Calnef Plus Softgel Capsule is likely safe to use. In some cases, it may cause side effects like constipation and stomach upset. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult a doctor.

Let your doctor know if you are using any other medicine, or herbal products before starting Calnef Plus Softgel Capsule . Please inform your doctor if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), malabsorption syndrome (difficulty absorbing nutrition from food), low levels of bile, and phosphate imbalance before starting Calnef Plus Softgel Capsule . If you are pregnant or breastfeeding, consult your doctor before taking Calnef Plus Softgel Capsule .

Uses of Calnef Plus Softgel Capsule

Treatment of Calcium and Calcitriol deficiency, Osteoporosis, Osteomalacia (Rickets), Vitamin D deficiency, Hypoparathyroidism, and Latent tetany

Directions for Use

Oral Suspension/Syrup: Shake the bottle well before use. Consume the recommended dose using the measuring cup.

Medicinal Benefits

Calnef Plus Softgel Capsule is used to treat low blood calcium levels. It effectively treats various conditions caused by low calcium levels in the body like vitamin D deficiency, osteoporosis, hypoparathyroidism, latent tetany, and rickets or osteomalacia. Calnef Plus Softgel Capsule consists of two medicines: Calcium (mineral) and Calcitriol (Vitamin D). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Calcitriol is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from food sources. It helps maintain blood calcium and phosphorus levels and mineralization of bone.

How Calnef Plus Softgel Capsule Works

Calnef Plus Softgel Capsule consists of calcium and calcitriol (vitamin D). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Calcitriol is a synthetic form of vitamin D that helps maintain blood calcium and phosphorus levels and mineralization of bone.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Calnef Plus Softgel Capsule

  • Constipation 
  • Stomach upset
  • Nausea/vomiting
  • Bone/muscle pain
  • Fast or pounding heartbeat
  • Headache

What if I have taken an overdose of Calnef Plus Softgel Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Calnef Plus Softgel Capsule may include changes in vision, constipation, decreased sexual desire, difficult or painful urination, difficulty thinking, dry mouth, feeling tired, fever or chills, hallucination (seeing things or hearing voices that do not exist), headache, increased thirst, increased urination, irregular heartbeat, loss of appetite, metallic taste in the mouth, muscle or bone pain, nausea, pale, fatty stools, runny nose, stomach pain, upset stomach, vomiting, weakness, weight loss, and yellowing of the skin or eyes. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

If you are allergic to Calnef Plus Softgel Capsule or any other medicines, please tell your doctor. If you are pregnant or planning to become pregnant, it is advised to inform your doctor before using Calnef Plus Softgel Capsule . Consult your doctor if you are pregnant or breastfeeding. Calnef Plus Softgel Capsule is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor before taking Calnef Plus Softgel Capsule if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance. Calnef Plus Softgel Capsule may contain sugar or sorbitol; hence caution should be taken in case of intolerance to sugars, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

Drug-Drug Interactions

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Calcium carbonateKetoconazole
Severe
Calcium carbonateDigoxin
Severe

Drug-Drug Interactions

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Calcium carbonateKetoconazole
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Calnef Plus Softgel Capsule 10's with Ketoconazole may decrease the effects of Ketoconazole.

How to manage the interaction:
Although there is an interaction, Calnef Plus Softgel Capsule 10's can be taken with Ketoconazole if prescribed by the doctor. However, maintain a gap of 2 or more hours between both medicines. Do not discontinue the medication without consulting a doctor.
Calcium carbonateDigoxin
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Calnef Plus Softgel Capsule 10's and Digoxin may increase the calcium levels may increase the effects of Digoxin

How to manage the interaction:
Although there is an interaction, Calnef Plus Softgel Capsule 10's can be taken with Digoxin if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
Calcium carbonatePatiromer calcium
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Calnef Plus Softgel Capsule 10's may lower the effectiveness of Patiromer calcium in binding potassium.

How to manage the interaction:
Although there is an interaction, Calnef Plus Softgel Capsule 10's can be taken with Patiromer calcium if prescribed by the doctor. Consult the prescriber if you experience symptoms such as metabolic alkalosis like nausea, vomiting, tremor, muscle twitching, lightheadedness, numbness or tingling, prolonged muscle spasms, slowed breathing, irregular heartbeat, and confusion. Do not discontinue the medication without a doctor's advice.
Calcium carbonateRaltegravir
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Calnef Plus Softgel Capsule 10's may interfere with the absorption of Raltegravir and reduce its effectiveness.

How to manage the interaction:
Taking Calnef Plus Softgel Capsule 10's with Raltegravir should be avoided. Consult the doctor if you have any concerns, the doctor may recommend alternatives that do not interact with raltegravir. Do not discontinue the medication without consulting a doctor.
Calcium carbonateDolutegravir
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Dolutegravir with Calnef Plus Softgel Capsule 10's can reduce the effectiveness of dolutegravir.

How to manage the interaction:
Although there is an interaction, Calnef Plus Softgel Capsule 10's can be taken with dolutegravir if prescribed by the doctor. However, dolutegravir and Calnef Plus Softgel Capsule 10's should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
Calcium carbonateGefitinib
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Calnef Plus Softgel Capsule 10's may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Calnef Plus Softgel Capsule 10's can be taken with Gefitinib if prescribed by the doctor. However, Gefitinib and Calnef Plus Softgel Capsule 10's should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
CalcitriolBurosumab
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Calnef Plus Softgel Capsule 10's and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.

How to manage the interaction:
There may be a possibility of interaction between Calnef Plus Softgel Capsule 10's and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolParicalcitol
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Paricalcitol and Calnef Plus Softgel Capsule 10's are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.

How to manage the interaction:
Concomitant use of Paricalcitol with Calnef Plus Softgel Capsule 10's can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolIsoniazid
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Isoniazid with Calnef Plus Softgel Capsule 10's may decrease the effects of Calnef Plus Softgel Capsule 10's.

How to manage the interaction:
Although there is an interaction, Calnef Plus Softgel Capsule 10's can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
CalcitriolRifapentine
Severe
How does the drug interact with Calnef Plus Softgel Capsule 10's:
Co-administration of Rifapentine with Calnef Plus Softgel Capsule 10's may decrease the effects of Calnef Plus Softgel Capsule 10's.

How to manage the interaction:
Although there is an interaction, Calnef Plus Softgel Capsule 10's can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in children's diets.
  • Eat daily a serving of broccoli, cabbage, spinach, and other green leafy vegetables.
  • Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D–fortified milk.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your children's meals.

Habit Forming

No

Therapeutic Class

VITAMINS

Calnef Plus Softgel Capsule Substitute

Substitutes safety advice
  • Ostovista Plus Softgel Capsule 10's

    12.60per tablet
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence, limit alcohol consumption while using Calnef Plus Softgel Capsule .

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Pregnancy

Caution

Consult your doctor if you are pregnant. Your doctor will weigh the potential risks and benefits before recommending this medicine.

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Breast Feeding

Caution

Consult your doctor before taking Calnef Plus Softgel Capsule if you are breastfeeding. Calnef Plus Softgel Capsule can pass into the breast milk. If this medicine is used during breastfeeding, monitoring the serum calcium levels of the mother and the infant is required.

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Driving

Safe

Calnef Plus Softgel Capsule usually does not affect your ability to drive.

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Liver

Consult your doctor

Consult your doctor if you have any history of liver diseases before taking Calnef Plus Softgel Capsule . Hepatic impairment/liver disease can alter the metabolism and therapeutic activity of certain Vitamin D forms.

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Kidney

Consult your doctor

You should seek a doctor's advice before starting Calnef Plus Softgel Capsule if you have kidney diseases like kidney stones or undergoing dialysis. Be cautious if you are undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Consult your doctor

Please consult your doctor. Your doctor will recommend a suitable dose based on your child's age, body weight and condition.

FAQs

Calnef Plus Softgel Capsule consists of two vitamins: Calcium and Calcitriol (vitamin D). Calcium is a mineral used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation. Calcitriol helps maintain blood calcium and phosphorus levels and mineralisation of bone.
Antacids may alter the absorption of Calcium from Calnef Plus Softgel Capsule . Hence it is advised to take Calnef Plus Softgel Capsule two hours before or four hours after taking antacids.
Calnef Plus Softgel Capsule is used to treat low levels of calcium in the body. Hence it is not advised to use Calnef Plus Softgel Capsule if you have hypercalcemia since higher calcium levels may lead to kidney stones and other effects.
Calnef Plus Softgel Capsule can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Calnef Plus Softgel Capsule as a daily supplement if you have any kidney problems or a history of kidney stones.
Milk is considered to be the best source of calcium. You can take Calnef Plus Softgel Capsule with milk.
The primary food sources of vitamin D are Oily fish, such as salmon and sardines, red meat, liver (avoid liver if you are pregnant), egg yolks, and fortified foods, such as some fat spreads and breakfast cereals are rich in sources of vitamin D.
The common side effects of Calnef Plus Softgel Capsule include constipation, stomach upset, nausea or vomiting, muscle pain, fast or repeated strike heartbeat, and headache.
Vitamin D is essential for maintaining strong bones, teeth, and muscles. It helps regulate calcium and phosphate levels in the body, ensuring these vital nutrients are used efficiently to keep the skeleton, smile, and muscles healthy and thriving.

Country of origin

India

Manufacturer/Marketer address

160, Innovation Colony, Jogani, Ramgopalpet, Hyderabad, Telangana 500003
Other Info - CAL2562

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