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Reviewed By Santoshini Reddy G , M Pharmacy
Aycal-Plus Softgel Capsule is a combination medicine primarily used to treat nutritional deficiencies, low calcium levels (hypocalcaemia), vitamin B6 deficiency, folate deficiency, and vitamin B12 deficiency. This medicine works by increasing the calcium and vitamin D levels in the body and regulates bodily functions, thus providing essential nutrients necessary for bone formation and maintenance. Common side effects include upset stomach, diarrhoea, drowsiness, flushing, and nausea.
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About Aycal-Plus Softgel Capsule

Aycal-Plus Softgel Capsule is used to treat nutritional deficiencies. Nutritional deficiency occurs when the body is unable to absorb or get enough nutrients from food. It could lead to various health problems, including defective bone growth, skin disorders, digestive issues, and dementia (memory loss). 

Aycal-Plus Softgel Capsule contains Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. Calcium carbonate makes the bones stronger by increasing their density. Calcitriol raises the Vitamin D levels and thereby increases calcium levels in the blood. Folic acid helps in producing new blood cells and prevents low folate levels. Vitamin B6 is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Methylcobalamin regulates body functions like cell multiplication, blood formation, and protein synthesis. 

Your doctor will decide the duration based on your medical condition. Sometimes, Aycal-Plus Softgel Capsule may cause common side effects like nausea, stomach upset, and diarrhoea. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult a doctor.

Let your doctor know if you use any other medicines before starting Aycal-Plus Softgel Capsule . If you are allergic to any of the components in Aycal-Plus Softgel Capsule , please inform your doctor. If you are pregnant or breastfeeding, please consult your doctor before taking Aycal-Plus Softgel Capsule . It is advised to avoid or limit alcohol consumption since it may affect calcium absorption. Aycal-Plus Softgel Capsule should not be given to children unless advised by a doctor.

Uses of Aycal-Plus Softgel Capsule

Management and treatment of Nutritional deficiencies

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Aycal-Plus Softgel Capsule is used to treat nutritional deficiencies and contains Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. Calcium carbonate makes the bones stronger by increasing their density. It helps treat and prevent low calcium levels. Calcitriol is a synthetic version of Vitamin D3 that treats calcium deficiency and improves Vitamin D levels. Folic acid helps form red blood cells and prevents DNA changes that lead to cancer. Vitamin B6 is a water-soluble vitamin involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Methylcobalamin regulates body functions like cell multiplication, blood formation, and protein synthesis.

How Aycal-Plus Softgel Capsule Works

Aycal-Plus Softgel Capsule contains Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. Calcium carbonate makes the bones stronger by increasing their density. Calcitriol raises the Vitamin D levels and thereby increases calcium levels in the blood. Folic acid helps in producing new blood cells and prevents low folate levels. Vitamin B6 is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Methylcobalamin regulates body functions like cell multiplication, blood formation, and protein synthesis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aycal-Plus Softgel Capsule

  • Nausea
  • Stomach upset
  • Diarrhoea

What if I have taken an overdose of Aycal-Plus Softgel Capsule

Avoid exceeding the recommended dose as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food) before starting Aycal-Plus Softgel Capsule . Let your doctor know if you have any heart/kidney/liver diseases or hypercalcaemia (excess calcium levels in the blood) before starting Aycal-Plus Softgel Capsule . If you are pregnant or breastfeeding, consult your doctor before taking Aycal-Plus Softgel Capsule . Drinking alcohol may hinder Aycal-Plus Softgel Capsule absorption; therefore, it is advised to limit the alcohol intake while using Aycal-Plus Softgel Capsule .

Drug-Drug Interactions

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CalcitriolBurosumab
Severe
CalcitriolParicalcitol
Severe

Drug-Drug Interactions

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CalcitriolBurosumab
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Aycal-Plus Softgel Capsule 10's and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.

How to manage the interaction:
There may be a possibility of interaction between Aycal-Plus Softgel Capsule 10's and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolParicalcitol
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Paricalcitol and Aycal-Plus Softgel Capsule 10's are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.

How to manage the interaction:
Concomitant use of Paricalcitol with Aycal-Plus Softgel Capsule 10's can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolIsoniazid
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Isoniazid with Aycal-Plus Softgel Capsule 10's may decrease the effects of Aycal-Plus Softgel Capsule 10's.

How to manage the interaction:
Although there is an interaction, Aycal-Plus Softgel Capsule 10's can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
CalcitriolRifapentine
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Rifapentine with Aycal-Plus Softgel Capsule 10's may decrease the effects of Aycal-Plus Softgel Capsule 10's.

How to manage the interaction:
Although there is an interaction, Aycal-Plus Softgel Capsule 10's can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
CalcitriolColecalciferol
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Cholecalciferol and Aycal-Plus Softgel Capsule 10's are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and Aycal-Plus Softgel Capsule 10's, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Taking Aycal-Plus Softgel Capsule 10's with Fosphenytoin can reduce the levels and efficacy of Aycal-Plus Softgel Capsule 10's.

How to manage the interaction:
Taking Aycal-Plus Softgel Capsule 10's with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolErgocalciferol
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Ergocalciferol and Aycal-Plus Softgel Capsule 10's are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Ergocalciferol with Aycal-Plus Softgel Capsule 10's can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolCalcifediol
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Calcifediol and Aycal-Plus Softgel Capsule 10's are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Aycal-Plus Softgel Capsule 10's with Calcifediol can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, such as irregular heart rhythm, seizures, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolCarbamazepine
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Aycal-Plus Softgel Capsule 10's with Carbamazepine may decrease the effects of Aycal-Plus Softgel Capsule 10's.

How to manage the interaction:
Although there is an interaction, Aycal-Plus Softgel Capsule 10's can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Aycal-Plus Softgel Capsule 10's:
Co-administration of Aycal-Plus Softgel Capsule 10's with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Aycal-Plus Softgel Capsule 10's can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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CALCIUM CARBONATE-500MG+CALCITRIOL-0.25MCG+FOLIC ACID-1.5MG+VITAMIN B6-3MG+METHYLCOBALAMIN-1500MCGPotassium rich foods
Moderate

Drug-Food Interactions

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CALCIUM CARBONATE-500MG+CALCITRIOL-0.25MCG+FOLIC ACID-1.5MG+VITAMIN B6-3MG+METHYLCOBALAMIN-1500MCGPotassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
Consumption of Spinach while on the treatment with Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine may decrease the blood levels of Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine. Avoid or limit consumption of Spinach while on the treatment with Calcitriol, Calcium carbonate, Folic acid, Mecobalamin, and Pyridoxine.

Diet & Lifestyle Advise

  • Try Vitamin B complex food sources like milk, cheese, eggs, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.

  • Try folate-rich food sources like broccoli, Brussels sprouts, leafy green vegetables, cabbage, kale, spring greens, spinach, peas, chickpeas, kidney beans, and breakfast cereals fortified with folic acid.

  • Include fruits like citrus, banana, and watermelon in your diet.

  • Avoid smoking and alcohol consumption.

  • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT

Aycal-Plus Softgel Capsule Substitute

Substitutes safety advice
  • Mecmaxol Softgel Capsule 10's

    by AYUR

    22.50per tablet
  • Calbona Softgel Capsule 10's

    by AYUR

    18.81per tablet
  • Calvin-M Capsule 10's

    13.50per tablet
  • Calct Forte Softgel Capsule 10's

    13.41per tablet
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Alcohol

Caution

It is advised to limit/avoid alcohol intake to ensure maximum absorption of nutrients.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant. Your doctor will recommend this medicine only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Pyridoxine is excreted into breast milk. Please consult your doctor before taking Aycal-Plus Softgel Capsule if you are a breastfeeding mother.

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Driving

Safe

Aycal-Plus Softgel Capsule usually does not interfere with your driving ability.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases before taking Aycal-Plus Softgel Capsule . Your dosage may be adjusted in case of liver impairment.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases before taking Aycal-Plus Softgel Capsule . Your dosage may be adjusted in case of renal impairment.

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Children

Caution

Do not use this medicine in children without recommended by your doctor.

FAQs

Aycal-Plus Softgel Capsule is used to treat and manage nutritional deficiencies.
Aycal-Plus Softgel Capsule is a vitamin supplement and consists of Calcium carbonate, Calcitriol, Folic acid, Vitamin B6, and Methylcobalamin. When you lack these vitamins in your body, Aycal-Plus Softgel Capsule helps replenish these deficient levels. Collectively, Aycal-Plus Softgel Capsule treats nutritional deficiencies.
Pyridoxine/Vitamin B6 in Aycal-Plus Softgel Capsule may interfere with laboratory tests like urine tests for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Aycal-Plus Softgel Capsule before undergoing blood and urine examinations.
Avoid taking more than one multivitamin product concomitantly unless advised by the doctor. Taking similar nutritional supplements simultaneously can lead to a vitamin overdose or other serious side effects.
Antacids may interfere with the absorption of Aycal-Plus Softgel Capsule . Hence, taking Aycal-Plus Softgel Capsule two hours before or four hours after taking antacids is advised.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Avoid or limit alcohol consumption while taking Aycal-Plus Softgel Capsule since it may affect calcium absorption. Let your doctor know if you are using antacids, anti-cancer drugs (altretamine, fluorouracil, capecitabine), fits medicines (phenytoin, phenobarbital), antibiotics (ceftriaxone, ketoconazole), HIV/AIDS medicines (dolutegravir), hormones (levothyroxine), water pills, high blood pressure medicines (diltiazem), and heart-related medicines (digoxin) as Aycal-Plus Softgel Capsule may interact with these medicines.
Calcium is essential for building and maintaining strong bones, supporting muscle movement, facilitating nerve communication and blood vessel movement, and releasing hormones that impact various body functions.
The amount of calcium you need depends on your age, sex and other factors. However, consult your doctor if you have any concerns.
The amount of calcium in your blood is determined via a calcium blood test. Blood calcium levels that are too high or too low can indicate a variety of illnesses, including kidney disease, thyroid disease, parathyroid abnormalities, bone disease, and more. Consult a doctor to help to assess the test results after receiving your report.
Yes, excess calcium can be harmful. It can lead to a condition called hypercalcemia, which occurs when there is too much calcium in the blood. Symptoms of hypercalcemia include excessive thirst, frequent urination, nausea, vomiting, constipation, abdominal pain, muscle weakness, confusion, and in severe cases, heart rhythm problems. If you experience any of these symptoms, please consult your doctor.
To manage low calcium levels, increase calcium intake from dairy, leafy greens, almonds, and fortified foods. Take calcium and vitamin D supplements only if suggested by your doctor. Get enough vitamin D and monitor calcium levels regularly. However, consult your doctor if you have any concerns.
It best to take any multivitamins after breakfast in the morning for better nutritional absorption. However, take Aycal-Plus Softgel Capsule as advised by your doctor.
The common side effects of Aycal-Plus Softgel Capsule are nausea, stomach upset, and diarrhoea. If these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

FLAT NO. 202, P.No-22/p, 2ND FLOOR, SAI ELITE,PADMANAGAR, PH -1,CHINTAL QUTHBULLAPUR, RANGAREDDI
Other Info - AYC0005

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