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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:17 PM IST
Alkazit Syrup is used to treat renal tubular acidosis, gout and kidney stones. It contains disodium hydrogen citrate, which works by removing excess uric acid from the blood through urine. In some cases, this medicine may cause side effects such as abdominal discomfort, diarrhoea, tiredness, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Zither Pharmaceutical Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

About Alkazit Syrup

Alkazit Syrup is a urinary alkaliser indicated for the treatment of renal tubular acidosis, gout and kidney stones. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. Renal tubular acidosis is a condition in which the kidneys fail to excrete acids into the urine; this causes the blood to remain too acidic.
 
Alkazit Syrup contains disodium hydrogen citrate, which metabolises to bicarbonate and increases the excretion of free bicarbonate ions; this increases the solubility of cysteine in the urine and ionises uric acid to soluble urate ion. This helps in increasing the urinary pH, thereby making the urine less acidic. 
 
You are advised to take Alkazit Syrup for as long as your doctor has suggested it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as abdominal discomfort, diarrhoea, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Alkazit Syrup if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Alkazit Syrup. It is not known if Alkazit Syrup affects your ability to drive; drive only if you are alert. Talk to a doctor before giving Alkazit Syrup to children. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Alkazit Syrup

Treatment of Renal tubular acidosis, Kidney stones.

Medicinal Benefits

Alkazit Syrup is a urinary alkaliser indicated for the treatment of renal tubular acidosis, gout and kidney stones. Alkazit Syrup contains disodium hydrogen citrate, which metabolises to bicarbonate and increases the excretion of free bicarbonate ions; this increases the solubility of cysteine in the urine and ionises uric acid to soluble urate ion. This helps in increasing the urinary pH, thereby making the urine less acidic. Alkazit Syrup may also help to treat urinary tract infections.

Directions for Use

The suggested dose of Alkazit Syrup should be diluted with a glass of water and taken after meals. Depending on your medical condition, your doctor will decide how long you must take Alkazit Syrup.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alkazit Syrup

  • Abdominal discomfort
  • Diarrhoea
  • Tiredness
  • Vomiting
  • Nausea

Drug Warnings

Do not take Alkazit Syrup if you are allergic to any of its contents. Inform your doctor if you have hyperkalaemia (high levels of potassium), hypocalcaemia (low blood calcium levels), high blood pressure, oedema, increased alkalinity in the blood, urinary tract infection, or kidney dysfunction. Consult your doctor before taking Alkazit Syrup if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Alkazit Syrup. It is not known if Alkazit Syrup affects your ability to drive; drive only if you are alert. Talk to a doctor before giving Alkazit Syrup to children.

Drug Interactions

Drug-Drug Interactions: Alkazit Syrup may interact with diuretics (furosemide), antibiotics (tetracycline), anti-arrhythmic (quinidine), adrenergic agonist (ephedrine), decongestant (pseudoephedrine), barbiturates, salicylates, and corticosteroids.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have hyperkalaemia (high levels of potassium), hypocalcaemia (low blood calcium levels), high blood pressure, oedema, increased alkalinity in the blood, urinary tract infection, or kidney dysfunction.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • TETRACYCLINE
  • QUINIDINE
  • EPHEDRINE
  • PSEUDOEPHEDRINE

Habit Forming

No

Diet & Lifestyle Advise

  • Drink plenty of fluids as they help in flushing out excess minerals.

  • Limit salt intake. High amounts of salt can increase the risk of kidney stones.

  • Maintain a healthy weight by exercising regularly.

  • Avoid foods rich in oxalates such as spinach, nuts, okra, dates, avocado, hot chocolate, cocoa, baked potato, French fries, and cereals, as they might increase the risk of oxalate stones.

Special Advise

  • Alkazit Syrup might interfere with urine ketone test. Inform the person doing the test that you are taking Alkazit Syrup.

Disease/Condition Glossary

Kidney stones: Nephrolithiasis, also known as kidney stones, is a disease affecting the urinary tract. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. They are the common cause of blood in urine and can be painful when passing through the urinary tract. Symptoms include severe pain, usually in one side of the abdomen and nausea. 

Renal tubular acidosis: It is a condition that involves the accumulation of acid in the body due to the failure of the kidneys to alkalise the urine appropriately. The kidneys fail to excrete acids into the urine, which causes the blood to remain too acidic. If not treated, it could lead to kidney stones, bone disease, kidney disease or failure.

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Alcohol

Caution

Avoid alcohol consumption while taking Alkazit Syrup.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Alkazit Syrup; your doctor will decide whether Alkazit Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

It is not known if Alkazit Syrup affects your ability to drive. Drive only if you are alert.

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Liver

Caution

Limited information is available regarding the usage of Alkazit Syrup in patients with hepatic impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Unsafe

Avoid taking Alkazit Syrup if you have kidney impairment. Please consult your doctor if you have kidney dysfunction or any concerns regarding this.

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Children

Caution

Limited information is available regarding the usage of Alkazit Syrup in children. Please consult a doctor.

Country of origin

India
Other Info - AL83773

Author Details

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FAQs

Alkazit Syrup is used to treat renal tubular acidosis and kidney stones.
Alkazit Syrup raises the urinary pH, thereby makes the urine less acidic. This helps the kidneys to get rid of excess uric acid, and prevents gout and the formation of kidney stones.
Consult your doctor before taking corticosteroids with Alkazit Syrup as it might increase the blood sodium levels.
Alkazit Syrup contains sodium; therefore, talk to your doctor before taking Alkazit Syrup if you are on a sodium-restricted diet or if you have high blood pressure.
To treat your condition effectually, continue taking Alkazit Syrup for as long as suggested. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Alkazit Syrup.
Diarrhoea might be a side-effect of Alkazit Syrup. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Consult a doctor before taking Alkazit Syrup if you have an active urinary tract infection, as Alkazit Syrup increases the urinary pH, which might promote further bacterial growth.
Limited information is available regarding the usage of Alkazit Syrup in children. Please consult a doctor.
Depending on your medical condition, you are advised to take Alkazit Syrup for as long as your doctor has suggested it for you. If you face any difficulty or experience any side effects that persist while taking this, seek medical attention.
Alkazit Syrup taken within few minutes to start working and its effect lasts for around four to six hours.
Alkazit Syrup taken within few minutes to start working and its effect lasts for around four to six hours.
No, Alkazit Syrup is not an antibiotic medication. Alkazit Syrup is a urinary alkaliser indicated for the treatment of renal tubular acidosis, gout and kidney stones.
Alkazit Syrup may interact with certain antibiotic medications. So, do not combine any antibiotic medication unless recommended by the doctor.
Yes, Alkazit Syrup may also help to treat urinary tract infections. However, consult your doctor to proper diagnosis and appropriate treatment.
The suggested dose of Alkazit Syrup should be diluted with a glass of water and taken after meals. Depending on your medical condition, your doctor will decide how long you must take Alkazit Syrup. Note: Adults may take it without dilution, followed by liquid, if preferred.
Take Alkazit Syrup only as suggested by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include electrolyte disturbances, nausea, vomiting, diarrhoea, oedema, hypernoia (excessive mental activity), and convulsions. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
Common side effects of Alkazit Syrup may include abdominal discomfort, diarrhoea, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

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