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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
ZYROP 3000IU INJECTION is used to treat anaemia due to chronic kidney disease and chemotherapy. It contains Erythropoietin alfa, human recombinant which works by stimulating the bone marrow to make more red blood cells. This medicine may sometimes cause side effects such as high blood pressure, nausea, vomiting and fever. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About ZYROP 3000IU INJECTION

ZYROP 3000IU INJECTION belongs to a class of drugs known as erythropoiesis-stimulating agent (ESA) primarily used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and anaemia due to chemotherapy (cancer treatment). Anaemia is reduced levels of haemoglobin and red blood cells (RBCs) in the blood. Chronic kidney disease (CKD) patients slowly develop anaemia, which gets worse as the disease progresses. Also, the treatment of cancer, including chemotherapy and radiotherapy, causes anaemia in cancer patients.

ZYROP 3000IU INJECTION contains ‘Erythropoietin alfa, human recombinant’. ZYROP 3000IU INJECTION works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This ZYROP 3000IU INJECTION is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC), preventing anaemia (lack of haemoglobin and RBC in the blood).

ZYROP 3000IU INJECTION will be administered by a healthcare professional; do not self-administer. You may experience high blood pressure, nausea, vomiting and fever. Most of these side effects of ZYROP 3000IU INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to ZYROP 3000IU INJECTION or any other medicines, please tell your doctor. ZYROP 3000IU INJECTION should not be taken in conditions like heart disease, high blood pressure, or liver disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using ZYROP 3000IU INJECTION. ZYROP 3000IU INJECTION may affect your ability to drive and use machines as ZYROP 3000IU INJECTION may cause fits disorder during the first 90 days of treatment. 

Uses of ZYROP 3000IU INJECTION

Treatment of Anemia due to chronic kidney disease, Anemia due to chemotherapy.

Medicinal Benefits

ZYROP 3000IU INJECTION helps in the treatment of anemia which may happen due to chronic kidney disease and cancer chemotherapy. ZYROP 3000IU INJECTION works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This ZYROP 3000IU INJECTION is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood). Besides this ZYROP 3000IU INJECTION is also used for the treatment of anemia caused by a medicine known as zidovudine for the treatment of HIV (human immunodeficiency viruses). ZYROP 3000IU INJECTION also decreases the requirement for blood cell transfusions.

Directions for Use

ZYROP 3000IU INJECTION will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ZYROP 3000IU INJECTION

  • High blood pressure
  • Nausea
  • Vomiting
  • Fever
  • Joint pain
  • Clotting at the injection site

Drug Warnings

If you are known to be allergic to ZYROP 3000IU INJECTION or any other medicines, please tell your doctor. ZYROP 3000IU INJECTION should not be taken in conditions like high blood pressure, heart disease, heart attack, blood clot in the brain (stroke), fits disorder, liver disease, or kidney disease. Before taking ZYROP 3000IU INJECTION inform your doctor if you have any type of cancer or skin reactions. If you are pregnant or a nursing mother, it is advised to consult a doctor before using ZYROP 3000IU INJECTION. ZYROP 3000IU INJECTION may affect your ability to drive and using machines as ZYROP 3000IU INJECTION may cause fits to disorder during the first 90 days of treatment. ZYROP 3000IU INJECTION should not be used for children below 1 month of age during treatment of anemia due to chronic kidney disease. ZYROP 3000IU INJECTION should not be used for children below 5 years of age during treatment of anemia due to chemotherapy.

Drug Interactions

Drug-Drug Interactions: ZYROP 3000IU INJECTION may have interaction with medicines used after kidney transplant (cyclosporine), other medicines for cancer and anemia (lenalidomide), medicines used for skin disease and cancer (thalidomide), anticancer (pomalidomide).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: ZYROP 3000IU INJECTION should not be used in patients with high blood pressure and fits disorder.

Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • LENALIDOMIDE
  • THALIDOMIDE
  • POMALIDOMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  • Your doctor may get your blood tests done frequently to examine the levels of blood cells, hemoglobin, and electrolytes such as potassium in your blood.
  • Eat food that is rich in iron, vitamin B12, and folic acid.
  • Eat food like leafy, green vegetables, fish, eggs, and liver.
  • Do mild to moderate exercise.

Disease/Condition Glossary

Anemia due to chronic kidney disease: Anemia describes reduced levels of hemoglobin and red blood cells (RBCs) in the blood. Chronic kidney disease (CKD) patients slowly develop anemia, which gets worse as the disease progresses. Then the kidneys partially lose their functions permanently in CKD. There is not sufficient erythropoietin (hormone formed by kidneys and produced RBC) formation. This hormone helps the production of RBCs by the bone marrow. As a result, RBC production is affected, leading to fewer RBCs than normal.

Anemia due to chemotherapy: Some types of cancer that affect blood and bone marrow, like blood cancer, and bone marrow cancer can decrease red blood cells. Also, the treatment of cancer, including chemotherapy and radiotherapy, causes anemia in cancer patients. This happens when a few medicines or radiation kill the red blood cells with the cancerous cells.

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Alcohol

Caution

It is not known that ZYROP 3000IU INJECTION may interact with alcohol. Therefore, avoid drinking alcohol while using ZYROP 3000IU INJECTION.

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Pregnancy

Caution

ZYROP 3000IU INJECTION should not be taken until prescribed. Your doctor will decide what is the best treatment for you. Please consult your doctor.

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Breast Feeding

Caution

Inform your doctor before taking ZYROP 3000IU INJECTION. Your doctor will advise you to either stop or continue treatment.

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Driving

Caution

ZYROP 3000IU INJECTION may affect your ability to drive and using machines as ZYROP 3000IU INJECTION may cause fits to disorder during the first 90 days of treatment.

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Liver

Caution

Take ZYROP 3000IU INJECTION with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

ZYROP 3000IU INJECTION is safely given to the kidney patients only if prescribed by your doctor.

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Children

Caution

ZYROP 3000IU INJECTION should be used in children only when prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ZYR0013

FAQs

ZYROP 3000IU INJECTION is used to treat anaemia (lack of haemoglobin in blood) due to chronic kidney disease and chemotherapy (cancer treatment).
Yes, ZYROP 3000IU INJECTION can be used for children above 1 month of age during treatment of anemia due to chronic kidney disease. ZYROP 3000IU INJECTION can be used for children above 5 years of age during treatment of anemia due to chemotherapy. The effectiveness of ZYROP 3000IU INJECTION and side effects observed in children is the same as adults, and used only when prescribed by a doctor.
Yes, ZYROP 3000IU INJECTION may increase the blood pressure. During initial treatment with ZYROP 3000IU INJECTION, blood pressure should be examined and those who have high blood pressure should take proper methods to regulate blood pressure. Your doctor may stop ZYROP 3000IU INJECTION if the blood pressure continues uncontrolled.
ZYROP 3000IU INJECTION works by stimulating the bone marrow (soft tissue within the bones that makes red blood cells) to make more red blood cells. This ZYROP 3000IU INJECTION is very similar to the natural substance in the body known as erythropoietin (hormone formed by kidneys and produced RBC) which prevents anemia (lack of hemoglobin and RBC in the blood).
The most common side effects of ZYROP 3000IU INJECTION are high blood pressure, nausea, vomiting, and fever, diarrhea, feeling upset in the stomach, skin rashes, stuffy nose, sore throat, bone, or muscle pain. Most of these side effects of ZYROP 3000IU INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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