Zygolet 2.5mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.
 
Zygolet 2.5mg Tablet contains 'Letrozole' that works by blocking the aromatase enzyme, which is involved in the production of the estrogen hormone. The cancer cells require estrogen for their growth. Hence, by blocking the aromatase enzyme, Zygolet 2.5mg Tablet prevents the growth of cancer cells. Thereby Zygolet 2.5mg Tablet helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts.

You are advised to take Zygolet 2.5mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Zygolet 2.5mg Tablet may cause certain common side-effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Do not be reluctant to talk with your doctor if you experience any of these side-effects persistently.
 
Avoid taking Zygolet 2.5mg Tablet if you are pregnant or breastfeeding. Zygolet 2.5mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Zygolet 2.5mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Zygolet 2.5mg Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications to rule out any side-effects.

Zygolet 2.5mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors. Zygolet 2.5mg Tablet is used to treat breast cancer in women who have gone through menopause (cessation of periods). Zygolet 2.5mg Tablet works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme Zygolet 2.5mg Tablet prevents the growth of cancer cells. Thereby, Zygolet 2.5mg Tablet helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.

• Hypercholesterolemia (increased cholesterol levels)
• Tiredness
• Weakness
• Increased sweating
• Feeling unwell
• Pain in joints
• Hot flushes (feeling of warmth)

Do not take Zygolet 2.5mg Tablet if you are allergic to any of its contents, if you have not yet gone through menopause (still get your periods). Talk to your doctor before taking Zygolet 2.5mg Tablet if you have osteoporosis (thinning of bones), bone fractures, severe liver or kidney disease. Zygolet 2.5mg Tablet may cause inflammation in tendons or tendon injury; contact your doctor if you observe any sign of tendon pain or swelling while taking Zygolet 2.5mg Tablet. Avoid taking Zygolet 2.5mg Tablet if you are pregnant or breastfeeding. Zygolet 2.5mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Zygolet 2.5mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Zygolet 2.5mg Tablet as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medications before taking Zygolet 2.5mg Tablet to rule out any side-effects. 

Drug-Drug Interactions: Zygolet 2.5mg Tablet may interact with antidepressants (citalopram, escitalopram) and anticancer (tamoxifen). 

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have high cholesterol, osteoporosis (thinning of bone), or liver disease.

• CITALOPRAM
• ESCITALOPRAM
• TAMOXIFEN

• Eat a healthy diet and exercise regularly to maintain proper weight.

• Avoid smoking and alcohol consumption.

• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.

• Avoid fast food, fried food, processed meats, refined carbs and added sugar.

• Get optimal sleep; rest well.

• Your doctor may advise you to regularly measure bone density before, during and after the treatment as Zygolet 2.5mg Tablet may cause bone thinning due to reduction of estrogens in the body.

• Zygolet 2.5mg Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Zygolet 2.5mg Tablet.

Breast cancer: It is a type of cancer that develops in breast cells which are stimulated by the female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.