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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Zycel MD 200 Tablet is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. It contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme responsible for causing pain and inflammation in the body. Thereby, it helps relieve pain and swelling. It may cause side effects such as indigestion, stomach pain, diarrhoea, oedema, and flatulence. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

CELECOXIB-200MG

Manufacturer/Marketer

Zydus Cadila

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zycel MD 200 Tablet

Zycel MD 200 Tablet is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. Arthritis is a condition that causes swelling of one or more joints, resulting in pain and stiffness of joints that worsen over time.

Zycel MD 200 Tablet contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme responsible for causing pain and inflammation in the body. Thereby, it helps relieve pain and swelling associated with different types of arthritis, spondylitis, low back pain, and menstrual pain.

Your doctor will advise you on how often you take this medicine based on your medical condition. In some cases, you may experience indigestion, stomach pain, diarrhoea, oedema, and flatulence. Most of these side effects of Zycel MD 200 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are known to be allergic to Zycel MD 200 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Zycel MD 200 Tablet . Do not consume alcohol with Zycel MD 200 Tablet as it may increase the risk of stomach bleeding. Zycel MD 200 Tablet may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal. It should not be used by a patient who has undergone recent heart bypass surgery or will have it. Zycel MD 200 Tablet increases the risk of severe gastrointestinal conditions like bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.

Uses of Zycel MD 200 Tablet

Treatment of Joint pain relief and menstrual cramps.

Medicinal Benefits

Zycel MD 200 Tablet contains 'pain killers' primarily used to reduce pain and swelling in muscles and joints in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in neck), menstrual pain. It contains Celecoxib, which works by blocking the action of cyclo-oxygenase (COX) enzyme in the body involved in producing certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it helps in relieving pain and swelling associated with different types of arthritis. 

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zycel MD 200 Tablet

  • Indigestion

  • Stomach pain

  • Diarrhea

  • Edema

  • Flatulence

  • Constipation

  • Headache

Drug Warnings

Do not take Zycel MD 200 Tablet if you are allergic to any of its ingredients. Zycel MD 200 Tablet may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal. It should not be used by the patient who has had undergone recent heart bypass surgery or will have it. Zycel MD 200 Tablet increases the risk of severe gastrointestinal conditions like bleeding, ulceration and perforation of the stomach or intestines, which can be fatal. Elderly patients are at greater risk for gastrointestinal bleeding problems so that the doctor can limit their dose. Zycel MD 200 Tablet is not recommended for pregnant women, especially in the third trimester as it may cause harm the unborn baby (fetus). Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Zycel MD 200 Tablet . Do not consume alcohol with Zycel MD 200 Tablet as it may increase the risk of stomach bleeding or ulcer. If you experience weight loss, diarrhoea, pain or vomiting, please stop taking Zycel MD 200 Tablet and consult a doctor immediately. These might be signs of worsening or Crohn’s disease or ulcerative colitis (swelling in the digestive tract).

Drug Interactions

Drug-Drug Interaction: Zycel MD 200 Tablet may have interaction with pain killers (ibuprofen, diclofenac, paracetamol, aspirin), high blood pressure-lowering medicines (propranolol, enalapril, losartan, candesartan), water pills (furosemide), blood thinners (heparin, warfarin, clopidogrel), fits related medicines (phenytoin), antidiabetic drugs (glimepiride, glipizide), antibiotics (moxifloxacin, ciprofloxacin), HIV/AIDS medicines (Zidovudine), Immuno-suppressants medicines (cyclosporine), cardiac drugs (digoxin), psychiatric medication (lithium).

Drug-Food Interaction: Zycel MD 200 Tablet may interact with alcohol. Therefore, avoid alcohol intake while taking Zycel MD 200 Tablet as it may increase the risk of stomach bleeding.

Drug-Disease Interaction: People with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver or heart problems and an autoimmune condition, such as systemic lupus erythematosus (joint pain, fever and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss) should consult a doctor before taking Zycel MD 200 Tablet .

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • DICLOFENAC
  • PARACETAMOL
  • ASPIRIN
  • PROPRANOLOL
  • ENALAPRIL
  • LOSARTAN
  • CANDESARTAN
  • FUROSEMIDE
  • HEPARIN
  • WARFARIN
  • CLOPIDOGREL
  • PHENYTOIN
  • GLIMEPIRIDE
  • GLIPIZIDE
  • MOXIFLOXACIN
  • CIPROFLOXACIN
  • ZIDOVUDINE
  • CYCLOSPORINE

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of a chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Special Advise

  • If you are elderly, a smoker, had a stroke previously, or have high blood pressure, diabetes or high cholesterol, please inform your doctor as these conditions may increase the risk of heart problems.

  • Regular monitoring of blood pressure as Zycel MD 200 Tablet may reduce the blood pressure-lowering effects of certain blood pressure drugs.

  • Zycel MD 200 Tablet may cause anemia,  monitor hemoglobin or hematorcrit in long term treatments.

  • Do not take more than the prescribed dose as it may cause Zycel MD 200 Tablet overdose and lead to symptoms such as heartburn, stomach upset, unconsciousness, dizziness, ringing or buzzing in ears, fits, fainting, diarrhea or excitation.

Disease/Condition Glossary

Arthritis: It is a condition that causes swelling of one or more joints, resulting in pain and stiffness of joints that worsen over time. There are different types of arthritis, of which osteoarthritis and rheumatoid arthritis are the most common types. The arthritis symptoms include joint pain, stiffness, redness, tenderness, swelling in and around joints and reduced movement of joints. The risk of arthritis increases with age, obesity, previous joint injury or family history. Proper medication, physiotherapy, or sometimes surgery may help reduce arthritis symptoms and enhance the quality of life. 

Menstrual cramps: It is a pain a woman feels in the abdomen/stomach due to menstruation (the breakdown of the inner wall of the uterus and the release of blood). 

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Alcohol

Unsafe

Taking alcohol, along with Zycel MD 200 Tablet , can increase the chances of gastrointestinal bleeding and kidney damage.

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Pregnancy

Unsafe

Zycel MD 200 Tablet is a category C pregnancy drug. It should not be given during pregnancy, especially during the last trimester, as it is known to cause fetal deformities.

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Breast Feeding

Caution

Zycel MD 200 Tablet is not recommended for breastfeeding women.

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Driving

Caution

Zycel MD 200 Tablet is not known to cause drowsiness, but if you feel sleepy, please do not operate or drive any machinery.

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Liver

Caution

If you have had a history of any liver-related diseases, please consult the doctor before taking medicine.

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Kidney

Caution

If you have had a history of any kidney-related diseases, please consult the doctor before taking medicine.

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Children

Caution

Zycel MD 200 Tablet is not recommended for children below the age of 2 years. For children aged above 2 years, take it in dose and duration as prescribed by your doctor.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ZYC0018

Author Details

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FAQs

Zycel MD 200 Tablet is used to reduce pain and swelling in muscles and joints. It treats pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain.
Zycel MD 200 Tablet contains Celecoxib, which works by blocking the action of pain-inducing chemical messenger cyclo-oxygenase (COX) enzyme in the body involved in producing certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, it helps in relieving pain and swelling associated with different types of arthritis.
Yes, Zycel MD 200 Tablet can be used to treat menstrual cramps. Zycel MD 200 Tablet is a pain killer that decreases pain and inflammation-inducing chemical messenger known as prostaglandin (PG) production in the body involved in making the uterus (womb) contract during periods.
Arthritis is a chronic condition of joints with pain and inflammation. Zycel MD 200 Tablet does not cure arthritis but relieves symptoms of arthritis-like joint pain, swelling and stiffness.
Yes, Zycel MD 200 Tablet may increase the risk of heart problems such as heart attack and stroke, especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Zycel MD 200 Tablet . However, it is recommended to take Zycel MD 200 Tablet in the dose and for the duration as prescribed by your doctor. It should be not used by the patient who has had recent heart bypass surgery (coronary artery bypass graft - CABG).
No, you are not recommended to take Zycel MD 200 Tablet with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
You should avoid using Zycel MD 200 Tablet if you have gastrointestinal ulcer/bleeding, undergone planned heart bypass surgery or pregnant for more than 30 weeks.
Zycel MD 200 Tablet may reduce the blood pressure-lowering effects of certain blood pressure drugs, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

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