Zycel 100 Capsule is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. Arthritis is a condition that causes swelling of one or more joints, resulting in pain and stiffness of joints that worsen over time.

Zycel 100 Capsule contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme responsible for causing pain and inflammation in the body. Thereby, it helps relieve pain and swelling associated with different types of arthritis, spondylitis, low back pain, and menstrual pain.

Your doctor will advise you on how often you take this medicine based on your medical condition. In some cases, you may experience indigestion, stomach pain, diarrhoea, oedema, and flatulence. Most of these side effects of Zycel 100 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are known to be allergic to Zycel 100 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Zycel 100 Capsule . Do not consume alcohol with Zycel 100 Capsule as it may increase the risk of stomach bleeding. Zycel 100 Capsule may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal. It should not be used by a patient who has undergone recent heart bypass surgery or will have it. Zycel 100 Capsule increases the risk of severe gastrointestinal conditions like bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.

Zycel 100 Capsule contains 'pain killers' primarily used to reduce pain and swelling in muscles and joints in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in neck), menstrual pain. It contains Celecoxib, which works by blocking the action of cyclo-oxygenase (COX) enzyme in the body involved in producing certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby, it helps in relieving pain and swelling associated with different types of arthritis. 

• Indigestion

• Stomach pain

• Diarrhea

• Edema

• Flatulence

• Constipation

• Headache

Do not take Zycel 100 Capsule if you are allergic to any of its ingredients. Zycel 100 Capsule may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal. It should not be used by the patient who has had undergone recent heart bypass surgery or will have it. Zycel 100 Capsule increases the risk of severe gastrointestinal conditions like bleeding, ulceration and perforation of the stomach or intestines, which can be fatal. Elderly patients are at greater risk for gastrointestinal bleeding problems so that the doctor can limit their dose. Zycel 100 Capsule is not recommended for pregnant women, especially in the third trimester as it may cause harm the unborn baby (fetus). Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Zycel 100 Capsule . Do not consume alcohol with Zycel 100 Capsule as it may increase the risk of stomach bleeding or ulcer. If you experience weight loss, diarrhoea, pain or vomiting, please stop taking Zycel 100 Capsule and consult a doctor immediately. These might be signs of worsening or Crohn’s disease or ulcerative colitis (swelling in the digestive tract).

Drug-Drug Interaction: Zycel 100 Capsule may have interaction with pain killers (ibuprofen, diclofenac, paracetamol, aspirin), high blood pressure-lowering medicines (propranolol, enalapril, losartan, candesartan), water pills (furosemide), blood thinners (heparin, warfarin, clopidogrel), fits related medicines (phenytoin), antidiabetic drugs (glimepiride, glipizide), antibiotics (moxifloxacin, ciprofloxacin), HIV/AIDS medicines (Zidovudine), Immuno-suppressants medicines (cyclosporine), cardiac drugs (digoxin), psychiatric medication (lithium).

Drug-Food Interaction: Zycel 100 Capsule may interact with alcohol. Therefore, avoid alcohol intake while taking Zycel 100 Capsule as it may increase the risk of stomach bleeding.

Drug-Disease Interaction: People with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver or heart problems and an autoimmune condition, such as systemic lupus erythematosus (joint pain, fever and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss) should consult a doctor before taking Zycel 100 Capsule .

• IBUPROFEN
• DICLOFENAC
• PARACETAMOL
• ASPIRIN
• PROPRANOLOL
• ENALAPRIL
• LOSARTAN
• CANDESARTAN
• FUROSEMIDE
• HEPARIN
• WARFARIN
• CLOPIDOGREL
• PHENYTOIN
• GLIMEPIRIDE
• GLIPIZIDE
• MOXIFLOXACIN
• CIPROFLOXACIN
• ZIDOVUDINE
• CYCLOSPORINE

• Include more glucosamine, chondroitin sulfate, vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

• Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

• In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of a chemical called cytokines, which ramp up inflammation.

• Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

• If you are elderly, a smoker, had a stroke previously, or have high blood pressure, diabetes or high cholesterol, please inform your doctor as these conditions may increase the risk of heart problems.

• Regular monitoring of blood pressure as Zycel 100 Capsule may reduce the blood pressure-lowering effects of certain blood pressure drugs.

• Zycel 100 Capsule may cause anemia,  monitor hemoglobin or hematorcrit in long term treatments.

• Do not take more than the prescribed dose as it may cause Zycel 100 Capsule overdose and lead to symptoms such as heartburn, stomach upset, unconsciousness, dizziness, ringing or buzzing in ears, fits, fainting, diarrhea or excitation.

Arthritis: It is a condition that causes swelling of one or more joints, resulting in pain and stiffness of joints that worsen over time. There are different types of arthritis, of which osteoarthritis and rheumatoid arthritis are the most common types. The arthritis symptoms include joint pain, stiffness, redness, tenderness, swelling in and around joints and reduced movement of joints. The risk of arthritis increases with age, obesity, previous joint injury or family history. Proper medication, physiotherapy, or sometimes surgery may help reduce arthritis symptoms and enhance the quality of life. 

Menstrual cramps: It is a pain a woman feels in the abdomen/stomach due to menstruation (the breakdown of the inner wall of the uterus and the release of blood).