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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 15, 2024 | 8:18 AM IST

Zybend Plus 400 mg/6 mg Chewable Tablet is used to treat parasitic worm infections. It can be used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. It contains Albendazole and Ivermectin, which work by keeping the worm from taking glucose and depleting its energy levels, leading to its immobilization. Also, it can kill the parasites by acting on the nervous system. It starves the worms by inducing paralysis, consequently leading them to death. It may cause common side effects such as stomach pain, nausea, vomiting, headache, dizziness, decrease in white blood cell count (leucopenia), vision problems, confusion, weakness, and difficulty walking. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zybend Plus 400 mg/6 mg Chewable Tablet

Zybend Plus 400 mg/6 mg Chewable Tablet is used to treat parasitic worm infections. Parasitic worm infections are intestinal worm infections that are caused by the ingestion of contaminated food and water. Zybend Plus 400 mg/6 mg Chewable Tablet can be used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. 

Zybend Plus 400 mg/6 mg Chewable Tablet contains ‘albendazole’ and ‘ivermectin’, which work by keeping the worm from taking glucose and depleting its energy levels, leading to its immobilization. Ivermectin can kill the parasites by acting on the nervous system. It starves the worms by inducing paralysis, consequently leading them to death.

You should take this medicine as prescribed by your doctor. The common side-effects of Zybend Plus 400 mg/6 mg Chewable Tablet are stomach pain, nausea, vomiting, headache, dizziness, decrease in white blood cell count (leucopenia), vision problems, confusion, weakness, and difficulty walking. Inform your doctor if any of these side effects persist or get worse.

You should not take Zybend Plus 400 mg/6 mg Chewable Tablet if you are allergic to ‘albendazole’, ‘ivermectin’, or any other ingredients present in it. Before taking Zybend Plus 400 mg/6 mg Chewable Tablet, inform your doctor if you have a medical history of meningitis, African sleeping sickness (an infection caused by the bite of the tsetse fly in African countries), or illness that weakens the immune system HIV. It may make you more prone to infections, so maintain proper hygiene. It may cause dizziness, so refrain from activities that require you to stay alert.

Uses of Zybend Plus 400 mg/6 mg Chewable Tablet

Zybend Plus 400 mg/6 mg Chewable Tablet is used to treat parasitic worm infections.

Medicinal Benefits

Zybend Plus 400 mg/6 mg Chewable Tablet contains ‘Albendazole’ and ‘Ivermectin’, which belong to the class of medications called ‘antihelmintic’. It is a broad-spectrum antibiotic used in the treatment of parasitic infections. It can kill the disease-causing worms and stop the spread of infection effectively. Albendazole interrupts the absorption of glucose by the worm leading to energy depletion. Ivermectin acts by paralyzing the worms, consequently leading them to death.

Directions for Use

Take this medicine as directed by your doctor. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zybend Plus 400 mg/6 mg Chewable Tablet

  • Stomach pain
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Decrease in white blood cell count (leucopenia)
  • Vision problems
  • Confusion
  • Weakness
  • Difficulty walking

Drug Warnings

Zybend Plus 400 mg/6 mg Chewable Tablet may cause suppression of the bone marrow and cause anaemia. Inform your doctor if you have/had liver disease and if you have any surgery, including dental surgery. Consult your doctor immediately if you experience seizures, extreme tiredness, behaviour changes, blurred vision, trouble walking, or neck pain while taking Zybend Plus 400 mg/6 mg Chewable Tablet. Consult your doctor if you notice unusual bleeding or bruising, as you may bleed or bruise easily while taking Zybend Plus 400 mg/6 mg Chewable Tablet. It may cause orthostatic hypotension (dizziness upon rising up quickly), so avoid standing up too quickly from a sitting or lying position.

Drug Interactions

Drug-Drug Interactions: Zybend Plus 400 mg/6 mg Chewable Tablet may interact with sedatives (phenobarbital and butalbital), anti-anxiety drugs (clonazepam, clozapine, and lorazepam), narcotics (sodium oxybate), a medication used to treat epilepsy (valproic acid), anthelmintic (praziquantel), corticosteroid (dexamethasone), antacid (cimetidine), anti-asthma (theophylline),

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Zybend Plus 400 mg/6 mg Chewable Tablet should be used with caution in patients with myelosuppression (bone marrow suppression), hepatobiliary dysfunction (liver and biliary disease), neurological disorder, meningitis (inflammation of the membranes of brain), sleeping sickness, HIV, and kidney dysfunction.

Drug-Drug Interactions Checker List

  • PHENOBARBITAL
  • BUTALBITAL
  • CLONAZEPAM
  • LORAZEPAM
  • SODIUM OXYBATE
  • VALPROIC ACID
  • PRAZIQUANTEL
  • DEXAMETHASONE
  • CIMETIDINE
  • THEOPHYLLINE
  • CLOZAPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands regularly with soap and water, especially after using the toilet and while eating.
  • Avoid eating raw fish and meat.
  • Thoroughly cook meat before eating.
  • Wash all fruits and vegetables properly before consuming them.
  • Wash or reheat food that has been around for a long time.
  • Avoid contact with soil that may be contaminated with faeces.
  • Avoid foods that have been kept open in the markets, as they can be contaminated.
  • Drink boiled and purified water.

Special Advise

  • Get up slowly and rest your feet on the floor for a few minutes before standing up to avoid orthostatic hypotension.

Disease/Condition Glossary

Parasitic worm infections: Parasitic worms are also called intestinal worms or helminths. They live in and feed on the hosts leading to weakness and diseases. Common types of intestinal worms are roundworms and flatworms, such as tapeworms and flukes. Worm infections could occur due to the consumption of contaminated water, food, or soil, contact with contaminated faeces, poor sanitization, or poor hygiene. Symptoms of worm infections include abdominal pain, diarrhoea, nausea, vomiting, gas, bloating, fatigue, unexplained weight loss, and dysentery (bloody stools).

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Alcohol

Caution

Zybend Plus 400 mg/6 mg Chewable Tablet may interact with alcohol and worsen the condition.

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Pregnancy

Caution

Zybend Plus 400 mg/6 mg Chewable Tablet is a category C drug and may cause toxic effects to the unborn baby. So, your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Zybend Plus 400 mg/6 mg Chewable Tablet may get excreted in the breast milk. So, your doctor may advise you to stop breastfeeding while taking this medicine.

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Driving

Caution

Zybend Plus 400 mg/6 mg Chewable Tablet may cause dizziness and vision problems, so refrain from driving or operating heavy machinery while using this medicine.

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Liver

Consult your doctor

Zybend Plus 400 mg/6 mg Chewable Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Zybend Plus 400 mg/6 mg Chewable Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Consult your doctor

Zybend Plus 400 mg/6 mg Chewable Tablet is not recommended for children.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ZYB0018

FAQs

Zybend Plus 400 mg/6 mg Chewable Tablet is used to treat parasitic worm infections. It can be used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites.
Zybend Plus 400 mg/6 mg Chewable Tablet is a combination of two antihelmintic drugs 'albendazole' and 'ivermectin'. It is used to treat a wide range of parasitic infections. It kills the parasite by keeping it from utilizing glucose and depleting its energy levels. It also paralyzes the insect, thereby leading it to death.
Zybend Plus 400 mg/6 mg Chewable Tablet usually improves your symptoms within 2 to 3 days after taking this medicine. however, you have to complete the course of therapy as prescribed by your doctor. If there is no improvement in your condition even after completion of the course, consult your doctor immediately.
Zybend Plus 400 mg/6 mg Chewable Tablet may cause vision problems such as blurred vision. Consult your doctor if your vision problem affects your daily activities.
Zybend Plus 400 mg/6 mg Chewable Tablet is not an antibiotic. It is an antihelmintic medication used to treat parasitic worm infections in the stomach and intestine.
You may require regular blood cell count and liver function monitoring during treatment with Zybend Plus 400 mg/6 mg Chewable Tablet. Zybend Plus 400 mg/6 mg Chewable Tablet might increase your chances of getting an infection, so maintain proper hygiene and try to stay away from people with infections, flu, or colds.
Common symptoms of intestinal worms are stomach (abdominal pain) pain, diarrhoea, nausea, vomiting, gas formation, bloating, fatigue, and unexplained weight loss.

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