Zukanorm-100 SR Tablet belongs to a class of anti-diabetic drugs called 'dipeptidyl peptidase 4 (DPP-4)' inhibitors used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Zukanorm-100 SR Tablet may be used alone or in combination with other medicines. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin or cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, which is also known as adult-onset diabetes.

Zukanorm-100 SR Tablet contains Vildagliptin which works by preventing the breakdown of a chemical messenger called the 'incretin' hormone. This hormone is released after the meal to stimulate the release of insulin from the pancreas. Zukanorm-100 SR Tablet increases the level of 'incretin' hormone so that sufficient insulin can be produced from the pancreas to lower raised blood sugar levels. Thus, Zukanorm-100 SR Tablet helps in controlling blood sugar levels in type 2 diabetes mellitus. 

Take Zukanorm-100 SR Tablet as prescribed. Your doctor will advise you how often you take Zukanorm-100 SR Tablet based on your medical condition. You may experience dizziness, nausea, headache, excessive sweating, low blood sugar levels, and trembling in some cases. Most of these side effects of Zukanorm-100 SR Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Zukanorm-100 SR Tablet or any other medicines, please tell your doctor. Zukanorm-100 SR Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, or are on dialysis, please inform your doctor before taking Zukanorm-100 SR Tablet . Avoid alcohol consumption with Zukanorm-100 SR Tablet as it may increase or decrease blood sugar levels. Zukanorm-100 SR Tablet is not recommended for patients with diabetic ketoacidosis and type-1 diabetes. If you have type 1 diabetes, diabetic ketoacidosis (excessive levels of blood acids called ketones),  or disease of pancreas, kidney, liver, or heart problems, inform your doctor before taking Zukanorm-100 SR Tablet .

Zukanorm-100 SR Tablet contains Vildagliptin, an anti-diabetic drug used to treat type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Zukanorm-100 SR Tablet prevents the breakdown of incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) that control blood sugar levels. Thereby increasing the levels of these two hormones, which are released after a meal. Zukanorm-100 SR Tablet increases insulin production by the pancreas and decreases glucagon production by the liver. Thus, it helps to control blood sugar levels and prevent further complications due to diabetes. Proper diet and regular exercise along with Zukanorm-100 SR Tablet , will give better results.

• Dizziness

• Nausea

• Headache

• Excessive sweating

• Low blood sugar levels

• Trembling

If you are allergic to Zukanorm-100 SR Tablet or any other medicines, please tell your doctor. Zukanorm-100 SR Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, or are on dialysis, please inform your doctor before taking Zukanorm-100 SR Tablet . Avoid alcohol consumption with Zukanorm-100 SR Tablet as it may increase or decrease blood sugar levels. Zukanorm-100 SR Tablet is not recommended for patients with diabetic ketoacidosis and type-1 diabetes. Take short, frequent meals and avoid prolonged fasting when taking Zukanorm-100 SR Tablet . Beware of hypoglycemia symptoms (low blood sugar), including sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience any of these symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and consult your doctor. Make sure to carry these with you at all times, especially during long travels. If you have type 1 diabetes, diabetic ketoacidosis (excessive levels of blood acids called ketones),  or disease of pancreas, kidney, liver, or heart problems, inform your doctor before taking Zukanorm-100 SR Tablet . 

Drug-Drug Interaction: Zukanorm-100 SR Tablet may have interaction with antipsychotics (aripiprazole, clozapine), corticosteroids (dexamethasone, prednisolone), medicines used to treat glaucoma (acetazolamide), cardiac stimulant (dopamine), thyroid medicines (levothyroxine), water tablets (bendroflumethiazide).

Drug-Food Interaction: Zukanorm-100 SR Tablet may interact with alcohol. Therefore, avoid consumption of alcohol with Zukanorm-100 SR Tablet as it may lead to high or low blood sugar levels.

Drug-Disease Interaction: If you have type 1 diabetes, diabetic ketoacidosis (excessive levels of blood acids called ketones),  disease of pancreas, kidney, liver or heart problems, inform your doctor before taking Zukanorm-100 SR Tablet .

• ARIPIPRAZOLE
• CLOZAPINE
• DEXAMETHASONE
• PREDNISOLONE
• ACETAZOLAMIDE
• DOPAMINE
• LEVOTHYROXINE SODIUM
• BENDROFLUMETHIAZIDE

• Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.

• Maintain healthy body weight as obesity is also related to the onset of diabetes.

• Maintain a low fat and a low sugar diet. Replace carbohydrates-containing foods with whole grains, fruits, and vegetables as carbohydrates turn to sugars leading to high blood sugar.

• Avoid consumption of alcohol and quit smoking.

Liver function tests are recommended before starting treatment with Zukanorm-100 SR Tablet , at 3 months intervals for the first year and at regular intervals thereafter to monitor the signs of increased liver enzymes.

Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin or are resistant to insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, which is also known as adult-onset diabetes. Type 2 diabetes symptoms include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, damaged retina of the eyes or blindness, loss of limbs, sexual dysfunction, and an increase in the chance of heart attack or stroke.