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Composition :
HYDROCHLOROTHIAZIDE-12.5MG + LOSARTAN-50MG
Manufacturer/Marketer :
Zoticus Pharmaceuticals
Consume Type :
ORAL
Return Policy :
Not Returnable
Drug-Drug Interactions
HydrochlorothiazideDofetilide
Critical
HydrochlorothiazideCisapride
Critical
Drug-Drug Interactions
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HydrochlorothiazideDofetilide
Critical
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Taking Dofetilide and Zotan H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Zotan H 50mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Dofetilide and Zotan H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Zotan H 50mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Taking Cisapride and Zotan H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Zotan H 50mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Cisapride and Zotan H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Zotan H 50mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
LosartanEnalapril
Severe
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Using enalapril together with Zotan H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Although taking Enalapril with Zotan H 50mg/12.5mg Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
Using enalapril together with Zotan H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Although taking Enalapril with Zotan H 50mg/12.5mg Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
LosartanAmiloride
Severe
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Coadministration of amiloride with Zotan H 50mg/12.5mg Tablet may increase potassium levels in the blood. 9High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).
How to manage the interaction:
Taking amiloride along with Zotan H 50mg/12.5mg Tablet may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of amiloride with Zotan H 50mg/12.5mg Tablet may increase potassium levels in the blood. 9High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).
How to manage the interaction:
Taking amiloride along with Zotan H 50mg/12.5mg Tablet may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanRamipril
Severe
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Coadministration of ramipril together with Zotan H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of ramipril together with Zotan H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanLisinopril
Severe
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Coadministration of Zotan H 50mg/12.5mg Tablet with Lisinopril can increase potassium levels.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Lisinopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Zotan H 50mg/12.5mg Tablet with Lisinopril can increase potassium levels.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Lisinopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LosartanPotassium citrate
Severe
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Coadministration of Zotan H 50mg/12.5mg Tablet with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Potassium citrate together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
Coadministration of Zotan H 50mg/12.5mg Tablet with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Potassium citrate together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
LosartanTizanidine
Severe
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Coadministration of Zotan H 50mg/12.5mg Tablet with Tizanidine can show additive effects which can lower the blood pressure and increase the risk and severity of side effects.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. While taking these medications, avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes). Do not stop using any medications without talking to a doctor.
Coadministration of Zotan H 50mg/12.5mg Tablet with Tizanidine can show additive effects which can lower the blood pressure and increase the risk and severity of side effects.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. While taking these medications, avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes). Do not stop using any medications without talking to a doctor.
LosartanTrimethoprim
Severe
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Coadministration of Zotan H 50mg/12.5mg Tablet with Trimethoprim can increase potassium levels which can lead to severe conditions like kidney problems.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Trimethoprim together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Zotan H 50mg/12.5mg Tablet with Trimethoprim can increase potassium levels which can lead to severe conditions like kidney problems.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Trimethoprim together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LosartanSpironolactone
Severe
How does the drug interact with Zotan H 50mg/12.5mg Tablet:
Coadministration of Zotan H 50mg/12.5mg Tablet with Spironolactone can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Spironolactone is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
Coadministration of Zotan H 50mg/12.5mg Tablet with Spironolactone can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.
How to manage the interaction:
Taking Zotan H 50mg/12.5mg Tablet with Spironolactone is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
Drug-Food Interactions
HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate
Drug-Food Interactions
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HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit Juice
How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Zotan H 50mg/12.5mg Tablet may cause high levels of potassium in blood. Also, coadministration of grapefruits and grapefruit juice with Zotan H 50mg/12.5mg Tablet may decrease the efficacy of losartan. Avoid consumption of potassium-containing salt substitutes, grapefruits and grapefruit juice while being treated with Zotan H 50mg/12.5mg Tablet.
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit Juice
How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Zotan H 50mg/12.5mg Tablet may cause high levels of potassium in blood. Also, coadministration of grapefruits and grapefruit juice with Zotan H 50mg/12.5mg Tablet may decrease the efficacy of losartan. Avoid consumption of potassium-containing salt substitutes, grapefruits and grapefruit juice while being treated with Zotan H 50mg/12.5mg Tablet.
Zotan H 50mg/12.5mg Tablet Substitute
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Product Substitutes
Alcohol
Unsafe
You are recommended not to consume alcohol and Zotan H 50mg/12.5mg Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.
Pregnancy
Unsafe
Zotan H 50mg/12.5mg Tablet is not recommended during pregnancy. This medicine may cause fetal damage and can affect the unborn baby (fetus).
Breast Feeding
Caution
Zotan H 50mg/12.5mg Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this.
Driving
Caution
Zotan H 50mg/12.5mg Tablet causes drowsiness and dizziness, so drive only if you are alert
Liver
Caution
Zotan H 50mg/12.5mg Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.
Kidney
Unsafe
Not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.
Children
Caution
Zotan H 50mg/12.5mg Tablet hasn’t been studied in children younger than 18 years of age. So, it shouldn’t be used in people younger than 18 years.
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