Zonisep 50 Capsule belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy (seizures/fits). Epilepsy is a sudden rush of electricity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual’s consciousness, movements, or sensations.

Zonisep 50 Capsule contains 'Zonisamide’ that reduces the abnormal and excessive activity of nerve impulses in the brain that cause fits or seizures. Thereby helps in controlling seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual’s consciousness, movements, or sensations. Zonisep 50 Capsule is used alone or in combination to treat and prevent partial seizures in adults and children above 6 years of age.

Take Zonisep 50 Capsule as prescribed by your doctor. You are advised to take Zonisep 50 Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, irritability, loss of appetite, memory impairment, double vision, confusion, depression, constipation, nausea, headache, uncontrolled movements. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Zonisep 50 Capsule for as long as your doctor has prescribed. Please do not stop taking Zonisep 50 Capsule without consulting your doctor to avoid worsening of seizures. Do not take Zonisep 50 Capsule if you are pregnant or planning for pregnancy unless prescribed by the doctor. Avoid taking Zonisep 50 Capsule while breastfeeding as it may cause side-effects in the breastfed babies. Zonisep 50 Capsule should not be given to children unless prescribed. Zonisep 50 Capsule causes drowsiness and dizziness, so drive if you are alert. Zonisep 50 Capsule should not be given to children unless prescribed. Avoid consuming alcohol along with Zonisep 50 Capsule as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience mood swings or suicidal tendencies. Zonisep 50 Capsule can cause permanent vision loss, inform your doctor immediately if you have any eye pain, redness, or any changes in your vision. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Zonisep 50 Capsule belongs to a group of medicines called anti-convulsants or anti-epileptics. Zonisep 50 Capsule is used to treat epilepsy/seizures/fits. Epilepsy is a sudden rush of electricity in the brain. Zonisep 50 Capsule works by blocking the sodium and calcium current in the brain and suppress the abnormal and excessive activity of nerve impulses in the brain that cause fits and pain. Thereby help in controlling seizures. Zonisep 50 Capsule is used alone or in combination to treat and prevent partial seizures and generalized seizures in adults. Zonisep 50 Capsule may be used as solo therapy or in combination in treating and preventing seizures in children above 6 years of age. Zonisep 50 Capsule is not associated with any psychological or physical dependence, and there is no potential for abuse.

• Dizziness
• drowsiness
• Irritability
• Loss of appetite
• Memory impairment
• Impaired coordination
• Double vision
• Confusion
• Kidney stones
• Diarrhoea
• Constipation
• Decreased blood levels of bicarbonates (a substance that prevents the blood from becoming acidic)

Do not take Zonisep 50 Capsule if you are allergic to Zonisamide or any of its contents. Avoid intake of Zonisep 50 Capsule if you are pregnant or planning for pregnancy unless prescribed by the doctor. Breastfeeding mothers should consult the doctor before using Zonisep 50 Capsule to pass into the breast milk and affect the baby. Zonisep 50 Capsule should not be given to children unless prescribed. Inform your doctor before taking Zonisep 50 Capsule if you have or had kidney and liver problems, glaucoma, high levels of ammonia, osteoporosis, depression, heart problems if you have low levels of bicarbonate in blood you have previously suffered from kidney stones. Do not stop taking Zonisep 50 Capsule without consulting your doctor to avoid worsening of seizure episodes. Zonisep 50 Capsule causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Zonisep 50 Capsule as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience mood swings or suicidal tendencies. Zonisep 50 Capsule can cause permanent vision loss, inform your doctor immediately if you have any eye pain, redness, or any changes in your vision.

Drug-Drug Interactions: Zonisep 50 Capsule may have interaction with an anti-depressant (amitriptyline, duloxetine, sertraline, fluoxetine), anti-convulsant (gabapentin, lamotrigine, pregabalin, phenytoin, topiramate), antipsychotic (aripiprazole, quetiapine, lithium), anti-anxiety (alprazolam, triazolam), antibiotics (erythromycin, clarithromycin, telithromycin, troleandomycin), pain killer (codeine, oxycodone, tramadol, morphine), antihistamine (diphenhydramine, chlorpheniramine, brompheniramine), and antifungal (ketoconazole, itraconazole, fluconazole).

Drug-Food Interactions: Avoid alcohol consumption while taking Zonisep 50 Capsule as it might cause increased dizziness and sleepiness. Herbal preparations containing St. John's wort should be avoided while taking Zonisep 50 Capsule .

Drug-Disease Interaction: Zonisep 50 Capsule may have interactions with disease conditions such as depression, liver disease, kidney dysfunction, suicidal tendency, irregular heartbeat, thyroid dysfunction, low bicarbonate levels in the blood, and blood disorders.

• AMITRIPTYLINE
• DULOXETINE
• SERTRALINE
• FLUOXETINE
• GABAPENTIN
• LAMOTRIGINE
• PREGABALIN
• PHENYTOIN
• TOPIRAMATE
• ARIPIPRAZOLE
• QUETIAPINE
• LITHIUM
• ALPRAZOLAM
• ERYTHROMYCIN
• CLARITHROMYCIN
• TELITHROMYCIN
• CHLORPHENIRAMINE
• CODEINE
• OXYCODONE
• TRAMADOL
• MORPHINE
• DIPHENHYDRAMINE
• KETOCONAZOLE
• ITRACONAZOLE
• FLUCONAZOLE
• TRIAZOLAM
• TROLEANDOMYCIN
• BROMPHENIRAMINE

• A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.

• Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.

• Rest well, get plenty of sleep.

• Avoid smoking and alcohol consumption.

• Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

• Prepare your living area; small changes may reduce the risk of physical injury during a seizure.

• Install an alarm or emergency device to get assistance during a seizure attack.

• Regular monitoring of bicarbonate levels while taking Zonisep 50 Capsule is advised to prevent low blood bicarbonate levels.
• Zonisep 50 Capsule may cause low blood cell count, so if you have any red or purple spots on the body, let your doctor know about this.

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements, or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorders, brain injury, or stroke.