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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 22, 2024 | 7:37 PM IST
Zonegran Tablet is used to treat epilepsy (seizures/fits). It contains Zonisamide that reduces the abnormal and excessive activity of nerve impulses in the brain that cause fits or seizures. Thereby helps in controlling seizures. In some cases, you may experience certain common side effects such as dizziness, irritability, loss of appetite, memory impairment, double vision, confusion, depression, constipation, nausea, headache, or uncontrolled movements. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

ZONISAMIDE-100MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zonegran Tablet

Zonegran Tablet belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy (seizures/fits). Epilepsy is a sudden rush of electricity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual’s consciousness, movements, or sensations.

Zonegran Tablet contains 'Zonisamide’ that reduces the abnormal and excessive activity of nerve impulses in the brain that cause fits or seizures. Thereby helps in controlling seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual’s consciousness, movements, or sensations. Zonegran Tablet is used alone or in combination to treat and prevent partial seizures in adults and children above 6 years of age.

Take Zonegran Tablet as prescribed by your doctor. You are advised to take Zonegran Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, irritability, loss of appetite, memory impairment, double vision, confusion, depression, constipation, nausea, headache, uncontrolled movements. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Zonegran Tablet for as long as your doctor has prescribed. Please do not stop taking Zonegran Tablet without consulting your doctor to avoid worsening of seizures. Do not take Zonegran Tablet if you are pregnant or planning for pregnancy unless prescribed by the doctor. Avoid taking Zonegran Tablet while breastfeeding as it may cause side-effects in the breastfed babies. Zonegran Tablet should not be given to children unless prescribed. Zonegran Tablet causes drowsiness and dizziness, so drive if you are alert. Zonegran Tablet should not be given to children unless prescribed. Avoid consuming alcohol along with Zonegran Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience mood swings or suicidal tendencies. Zonegran Tablet can cause permanent vision loss, inform your doctor immediately if you have any eye pain, redness, or any changes in your vision. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Zonegran Tablet

Treatment of Epilepsy/Seizures.

Medicinal Benefits

Zonegran Tablet belongs to a group of medicines called anti-convulsants or anti-epileptics. Zonegran Tablet is used to treat epilepsy/seizures/fits. Epilepsy is a sudden rush of electricity in the brain. Zonegran Tablet works by blocking the sodium and calcium current in the brain and suppress the abnormal and excessive activity of nerve impulses in the brain that cause fits and pain. Thereby help in controlling seizures. Zonegran Tablet is used alone or in combination to treat and prevent partial seizures and generalized seizures in adults. Zonegran Tablet may be used as solo therapy or in combination in treating and preventing seizures in children above 6 years of age. Zonegran Tablet is not associated with any psychological or physical dependence, and there is no potential for abuse.

Directions for Use

Swallow Zonegran Tablet as a whole with a glass of water; do not chew or crush the medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zonegran Tablet

  • Dizziness
  • drowsiness
  • Irritability
  • Loss of appetite
  • Memory impairment
  • Impaired coordination
  • Double vision
  • Confusion
  • Kidney stones
  • Diarrhoea
  • Constipation
  • Decreased blood levels of bicarbonates (a substance that prevents the blood from becoming acidic)

Drug Warnings

Do not take Zonegran Tablet if you are allergic to Zonisamide or any of its contents. Avoid intake of Zonegran Tablet if you are pregnant or planning for pregnancy unless prescribed by the doctor. Breastfeeding mothers should consult the doctor before using Zonegran Tablet to pass into the breast milk and affect the baby. Zonegran Tablet should not be given to children unless prescribed. Inform your doctor before taking Zonegran Tablet if you have or had kidney and liver problems, glaucoma, high levels of ammonia, osteoporosis, depression, heart problems if you have low levels of bicarbonate in blood you have previously suffered from kidney stones. Do not stop taking Zonegran Tablet without consulting your doctor to avoid worsening of seizure episodes. Zonegran Tablet causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Zonegran Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience mood swings or suicidal tendencies. Zonegran Tablet can cause permanent vision loss, inform your doctor immediately if you have any eye pain, redness, or any changes in your vision.

Drug Interactions

Drug-Drug Interactions: Zonegran Tablet may have interaction with an anti-depressant (amitriptyline, duloxetine, sertraline, fluoxetine), anti-convulsant (gabapentin, lamotrigine, pregabalin, phenytoin, topiramate), antipsychotic (aripiprazole, quetiapine, lithium), anti-anxiety (alprazolam, triazolam), antibiotics (erythromycin, clarithromycin, telithromycin, troleandomycin), pain killer (codeine, oxycodone, tramadol, morphine), antihistamine (diphenhydramine, chlorpheniramine, brompheniramine), and antifungal (ketoconazole, itraconazole, fluconazole).

Drug-Food Interactions: Avoid alcohol consumption while taking Zonegran Tablet as it might cause increased dizziness and sleepiness. Herbal preparations containing St. John's wort should be avoided while taking Zonegran Tablet .

Drug-Disease Interaction: Zonegran Tablet may have interactions with disease conditions such as depression, liver disease, kidney dysfunction, suicidal tendency, irregular heartbeat, thyroid dysfunction, low bicarbonate levels in the blood, and blood disorders.

Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • SERTRALINE
  • FLUOXETINE
  • GABAPENTIN
  • LAMOTRIGINE
  • PREGABALIN
  • PHENYTOIN
  • TOPIRAMATE
  • ARIPIPRAZOLE
  • QUETIAPINE
  • LITHIUM
  • ALPRAZOLAM
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • CHLORPHENIRAMINE
  • CODEINE
  • OXYCODONE
  • TRAMADOL
  • MORPHINE
  • DIPHENHYDRAMINE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • FLUCONAZOLE
  • TRIAZOLAM
  • TROLEANDOMYCIN
  • BROMPHENIRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.

  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.

  • Rest well, get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Special Advise

  • Regular monitoring of bicarbonate levels while taking Zonegran Tablet is advised to prevent low blood bicarbonate levels.
  • Zonegran Tablet may cause low blood cell count, so if you have any red or purple spots on the body, let your doctor know about this.

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements, or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorders, brain injury, or stroke.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zonegran Tablet as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Zonegran Tablet if you are pregnant unless prescribed by a doctor to lead to serious birth defects/congenital disabilities. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Zonegran Tablet should not be taken by breastfeeding mothers as it passes into breast milk and could lead to side-effects for breastfed babies.

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Driving

Unsafe

Zonegran Tablet causes drowsiness, sleepiness, and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Zonegran Tablet can be given to children above 6 years if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

Country of origin

INDIA

Manufacturer/Marketer address

1st Floor, B Wing,Marwah Centre, Krishanlal Marwah Marg, Andheri ( East ), Mumbai - 400072, India
Other Info - ZON0025

Author Details

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FAQs

Zonegran Tablet belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy (seizures/fits).
Zonegran Tablet consists of 'zonisamide' that decreases the brain's excessive and abnormal nerve activity by blocking sodium and calcium currents in your brain and body. This reduces abnormal electrical activity between your nerve cells.
Consult your doctor before taking Zonegran Tablet if you are pregnant or planning for pregnancy. Your doctor will prescribe Zonegran Tablet only if the benefits outweigh the risks. If you are planning for pregnancy, use contraception while taking Zonegran Tablet .
Zonegran Tablet should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever. To avoid this condition, it is advisable to drink a lot of cold fluid and water, move to a cooler place, especially in summer.
No, Zonegran Tablet is not a habit-forming drug. However, it can cause side-effects, especially when you stop taking it suddenly.
Do not discontinue Zonegran Tablet without consulting your doctor. To treat your condition effectually continue taking Zonegran Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Zonegran Tablet ; your doctor will gradually reduce the dose to avoid precipitating seizures.
Consult your doctor before taking Zonegran Tablet if you have had kidney stones. Your doctor will prescribe Zonegran Tablet only if the benefits outweigh the risks. Zonegran Tablet should be taken with caution in patients with kidney stones. You may be at increased risk of developing more kidney stones. Reduce the risk of kidney stones, drink sufficient water.
Consult your doctor before taking Zonegran Tablet if you have glaucoma. Zonegran Tablet is contraindicated in patients with narrow-angle glaucoma. Zonegran Tablet may cause blindness on long-term use in the case of patients with narrow-angle glaucoma.
Zonegran Tablet contains Zonisamide as an active key ingredient.
If you suddenly stop taking Zonegran Tablet , your seizures may become worse. If required, your doctor will probably decrease your dose gradually.
In patients taking Zonegran Tablet , severe muscle pain and/or weakness develop either in the presence or absence of a fever. It is recommended that you consult your doctor; they will perform specific tests to evaluate muscle damage and treat it accordingly.
Although the Food and Drug Administration (FDA) has not officially approved Zonegran Tablet for children, quite a few research studies have shown that it has been given to children of various ages (even infants) with generally good results. However, it should be provided under the supervision of a doctor.
Suicidal tendencies are not a common side effect with Zonegran Tablet . However, consult your doctor immediately if you experience mood swings or suicidal tendencies.
Yes, Zonegran Tablet may lead to weight loss. A side effect of Zonisamide is reduced appetite and subsequent weight loss.
No, it does not impact on birth control pills. No reported interactions have been established as of now.
Zonegran Tablet is excreted by the kidneys; patients with renal impairment or renal disease should be treated cautiously.
In some cases, you may experience certain common side effects such as dizziness, irritability, loss of appetite, memory impairment, double vision, confusion, depression, constipation, nausea, headache, and uncontrolled movements. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Symptoms of overdose may include slow heartbeat, slowed breathing, dizziness, fainting and coma (loss of consciousness for a period of time).
Zonegran Tablet may help control your condition but will not cure it. It may take two weeks or longer before you feel the full benefit of Zonegran Tablet .
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Taking more than the recommended dosage does not provide additional benefits and can increase the risk of adverse effects.
Avoid consuming alcohol along with Zonegran Tablet as it could lead to increased dizziness and sleepiness.

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