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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Zolsoma 10 Tablet is used in the treatment of insomnia. It contains Zolpidem and Melatonin which relaxes muscles, reduces anxiety, and helps to fall asleep. It may cause side effects such as nausea, headache, diarrhoea, drowsiness, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Pulse Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zolsoma 10 Tablet

Zolsoma 10 Tablet is a combination medication containing 'sedative-hypnotics' used in the treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

Zolsoma 10 Tablet contains Zolpidem and Melatonin, primarily used to treat insomnia. Zolpidem works by increasing the activity of GABA, which is a chemical messenger in the brain, acting as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep).  Thus, Zolsoma 10 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Take Zolsoma 10 Tablet as prescribed by your doctor. You are advised to take Zolsoma 10 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take Zolsoma 10 Tablet empty stomach and just before bedtime. In some cases, you may experience nausea, headache, diarrhoea, drowsiness, and dizziness. Most of these side effects of Zolsoma 10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are pregnant, planning to become pregnant, or breastfeeding, please inform your doctor before starting Zolsoma 10 Tablet . Do not stop taking Zolsoma 10 Tablet even if you feel better, as it may lead to unpleasant side effects. Zolsoma 10 Tablet is known to cause drowsiness, so do not drive or operate machinery. Avoid consumption of alcohol as it may reduce the effectiveness of Zolsoma 10 Tablet . Zolsoma 10 Tablet should not be used for daily naps.

Uses of Zolsoma 10 Tablet

Treatment of Insomnia (sleeplessness).

Medicinal Benefits

Zolsoma 10 Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep). Thus, Zolsoma 10 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep. Appropriate lifestyle changes are recommended along with Zolsoma 10 Tablet to improve the quality of sleep.

Directions for Use

Swallow Zolsoma 10 Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zolsoma 10 Tablet

  • Nausea
  • Headache
  • Diarrhoea
  • Drowsiness
  • Dizziness

Drug Warnings

Do not take Zolsoma 10 Tablet if you are allergic to Zolsoma 10 Tablet or any of its ingredients. If you notice that the tablets are not working as well as they did in the beginning of the treatment, please consult a doctor as you might have developed tolerance to Zolsoma 10 Tablet , and dose adjustment may be required. Zolsoma 10 Tablet contains Zolpidem, a category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using Zolsoma 10 Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Zolsoma 10 Tablet . Maintain a time gap of a minimum of 8 hours between taking Zolsoma 10 Tablet and driving to reduce the risk of increased adverse effects.

Drug Interactions

Drug-Drug Interaction: Zolsoma 10 Tablet may have interaction with high blood pressure-lowering medicines (metoprolol), opioid pain killers (hydrocodone), antidepressants (sertraline), antibiotics (ciprofloxacin, rifampicin), antifungal drugs (ketoconazole), anti-anxiety drugs (alprazolam), antiallergics/antihistamines (diphenhydramine), muscle relaxants (cyclobenzaprine), antiepileptic drugs (gabapentin), stomach ulcer medicines (cimetidine), hypnotics (midazolam).

Drug-Food Interaction: Zolsoma 10 Tablet may interact with caffeine, St John’s wort (herbal medicine for treating depression) and may reduce the effectiveness of Zolsoma 10 Tablet . Also, avoid alcohol intake as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process and reduced physical movements), sleepwalking, or sleep-driving.

Drug-Disease Interaction: Do not take Zolsoma 10 Tablet if you have severe liver disease, breathing problems, sleep apnoea (sudden stopping of breathing during sleep), severe muscle weakness, diabetes, kidney problems, or any history of depression or mental illness.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • HYDROCODONE
  • SERTRALINE
  • CIPROFLOXACIN
  • RIFAMPICIN
  • KETOCONAZOLE
  • ALPRAZOLAM
  • DIPHENHYDRAMINE
  • CYCLOBENZAPRINE
  • GABAPENTIN
  • CIMETIDINE
  • MIDAZOLAM

Habit Forming

Yes

Diet & Lifestyle Advise

  • Do regular exercise during day time.
  • Do not take a nap during day time. Set regular timings to go to bed and wake up.
  • Relax at least 1 hour before bedtime by bathing with warm water, listening to music, or reading a book.
  • Make the bedroom dark and quiet, and ensure that your pillows and mattresses are comfortable.
  • Avoid watching tv, using mobiles or laptops just before bedtime.
  • Limit caffeine intake, including tea, coffee, hot chocolate, cola, and energy drinks, as it may reduce the effectiveness of Zolsoma 10 Tablet .
  • Avoid alcohol consumption as it may increase the risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleepwalking, or sleep-driving.

Special Advise

  • You are advised to take Zolsoma 10 Tablet on an empty stomach as taking Zolsoma 10 Tablet with food may reduce the effect of Zolsoma 10 Tablet .
  • If you are depressed or have depression in the past, please inform your doctor before taking Zolsoma 10 Tablet as it may increase self-harming or suicidal thoughts.
  • If you notice any behavioural side effects such as delusions (false belief), nightmares, irritability, restlessness, aggressiveness, or hallucinations (hear, feel or see things that are actually not present), please contact your doctor.
  • If you are allergic to any sugars, inform your doctor as Zolsoma 10 Tablet contains lactose.

Disease/Condition Glossary

Insomnia: It is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to a few weeks and occurs due to stress or life changes. Chronic insomnia may last from more than 3 nights per week to more than 3 months. Insomnia is mostly caused due to depression, stress, anxiety, jet lag, shift work, uncomfortable beds, chronic illness, caffeine, nicotine, alcohol intake, or certain medicines. It may be treated using sleeping pills, behaviour therapy, sleep habits changes, and identifying and treating chronic conditions.

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Alcohol

Unsafe

Avoid consumption of alcohol with Zolsoma 10 Tablet as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process, and reduced physical movements), sleepwalking, or sleep-driving.

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Pregnancy

Unsafe

Zolsoma 10 Tablet contains Zolpidem, a Category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Zolsoma 10 Tablet as it may be excreted in breast milk.

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Driving

Unsafe

You may experience dizziness, drowsiness, confusion, decreased alertness, blurred, or double vision, especially the day after taking Zolsoma 10 Tablet . Therefore, avoid driving if you feel drowsy or dizzy after taking Zolsoma 10 Tablet .

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Liver

Caution

Take Zolsoma 10 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zolsoma 10 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Zolsoma 10 Tablet is not recommended for children below 18 years of age.

Country of origin

INDIA

Manufacturer/Marketer address

4F10, Ballad Estates, Tarnaka, Hyderabad - 500017, TS, India.
Other Info - ZOL0009

Author Details

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FAQs

Zolsoma 10 Tablet is used in the treatment of insomnia.
Zolsoma 10 Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep)
No, Zolsoma 10 Tablet is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have a history of depression, please inform your doctor before taking Zolsoma 10 Tablet .
You are recommended to take Zolsoma 10 Tablet just before bedtime as it helps to sleep quickly and improves sleep quality. If you forget to take Zolsoma 10 Tablet at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.
No, you are not recommended to take Zolsoma 10 Tablet with hydrocodone or other opioid pain killers such as oxycodone, naloxone, and tramadol as co-administration of these medicines with Zolsoma 10 Tablet may increase the risk of difficulty in breathing, drowsiness, coma, and even death. However, before using Zolsoma 10 Tablet with any other medicines, you are advised to contact your doctor so that the dose may be adjusted to use safely.
Yes, Zolsoma 10 Tablet may cause dependence (mental and physical effects caused due to compulsion of taking Zolsoma 10 Tablet ) if used in high doses and for a prolonged time. This risk of dependency on Zolsoma 10 Tablet increases in patients who have a history of drug or alcohol abuse.

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