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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zolsoma 10 Tablet is used in the treatment of insomnia. It contains Zolpidem and Melatonin which relaxes muscles, reduces anxiety, and helps to fall asleep. It may cause side effects such as nausea, headache, diarrhoea, drowsiness, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Pulse Pharmaceuticals

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Zolsoma 10 Tablet

Zolsoma 10 Tablet is a combination medication containing 'sedative-hypnotics' used in the treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

Zolsoma 10 Tablet contains Zolpidem and Melatonin, primarily used to treat insomnia. Zolpidem works by increasing the activity of GABA, which is a chemical messenger in the brain, acting as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep).  Thus, Zolsoma 10 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Take Zolsoma 10 Tablet as prescribed by your doctor. You are advised to take Zolsoma 10 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take Zolsoma 10 Tablet empty stomach and just before bedtime. In some cases, you may experience nausea, headache, diarrhoea, drowsiness, and dizziness. Most of these side effects of Zolsoma 10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are pregnant, planning to become pregnant, or breastfeeding, please inform your doctor before starting Zolsoma 10 Tablet . Do not stop taking Zolsoma 10 Tablet even if you feel better, as it may lead to unpleasant side effects. Zolsoma 10 Tablet is known to cause drowsiness, so do not drive or operate machinery. Avoid consumption of alcohol as it may reduce the effectiveness of Zolsoma 10 Tablet . Zolsoma 10 Tablet should not be used for daily naps.

Uses of Zolsoma 10 Tablet

Treatment of Insomnia (sleeplessness).

Directions for Use

Swallow Zolsoma 10 Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Zolsoma 10 Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep). Thus, Zolsoma 10 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep. Appropriate lifestyle changes are recommended along with Zolsoma 10 Tablet to improve the quality of sleep.

How Zolsoma 10 Tablet Works

Zolsoma 10 Tablet contains Zolpidem and Melatonin, primarily used to treat insomnia. Zolpidem works by increasing the activity of GABA, which is a chemical messenger in the brain, acting as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep).  Thus, Zolsoma 10 Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zolsoma 10 Tablet

  • Nausea
  • Headache
  • Diarrhoea
  • Drowsiness
  • Dizziness

What if I have taken an overdose of Zolsoma 10 Tablet

Do not take more than the prescribed dose of Zolsoma 10 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Zolsoma 10 Tablet if you are allergic to Zolsoma 10 Tablet or any of its ingredients. If you notice that the tablets are not working as well as they did in the beginning of the treatment, please consult a doctor as you might have developed tolerance to Zolsoma 10 Tablet , and dose adjustment may be required. Zolsoma 10 Tablet contains Zolpidem, a category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using Zolsoma 10 Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Zolsoma 10 Tablet . Maintain a time gap of a minimum of 8 hours between taking Zolsoma 10 Tablet and driving to reduce the risk of increased adverse effects.

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
ZolpidemEsketamine
Severe

Drug-Drug Interactions

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ZolpidemSodium oxybate
Critical
How does the drug interact with Zolsoma 10 Tablet 10's:
Using sodium oxybate together with Zolsoma 10 Tablet 10's can significantly increase the risk of severity of low blood pressure, breathing difficulties, fainting and unconsciousness.

How to manage the interaction:
Taking Sodium oxybate with Zolsoma 10 Tablet 10's is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate consult a doctor immediately. You should refrain from operating any dangerous machinery or driving a car. Do not stop using any medications without talking to a doctor.
ZolpidemEsketamine
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Taking Zolsoma 10 Tablet 10's with Esketamine increases the effects of Zolsoma 10 Tablet 10's. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Esketamine and Zolsoma 10 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.
ZolpidemTramadol
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Using Zolsoma 10 Tablet 10's together with Tramadol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Tramadol and Zolsoma 10 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemTapentadol
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Using Zolsoma 10 Tablet 10's together with Tapentadol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Zolsoma 10 Tablet 10's with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemKetamine
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Taking Zolsoma 10 Tablet 10's with Ketamine increases the effects of Zolsoma 10 Tablet 10's. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Ketamine and Zolsoma 10 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should wait until the following day to operate any dangerous machinery or drive a car. Do not discontinue any medications without consulting a doctor.
ZolpidemDezocine
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Using Zolsoma 10 Tablet 10's together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Zolsoma 10 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.
ZolpidemPindolol
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Taking Zolsoma 10 Tablet 10's with Pindolol may increase the risk of low blood pressure.

How to manage the interaction:
Although taking Pindolol and Zolsoma 10 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemPethidine
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Taking Zolsoma 10 Tablet 10's with Pethidine may increase the risk of central nervous system depression, which can lead to breathing difficulty and unconsciousness.

How to manage the interaction:
Although taking Pethidine and Zolsoma 10 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. Do not discontinue any medications without consulting a doctor.
ZolpidemAlfentanil
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Using Zolsoma 10 Tablet 10's together with Alfentanil may increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Alfentanil and Zolsoma 10 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, or impairment in judgment consult a doctor. Do not stop using any medications without a doctor's advice.
ZolpidemOxycodone
Severe
How does the drug interact with Zolsoma 10 Tablet 10's:
Using Zolsoma 10 Tablet 10's together with Oxycodone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Oxycodone and Zolsoma 10 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, impairment in judgment, or reaction speed, consult a doctor. You should refrain from using dangerous machinery or driving a car. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ZOLPIDEM-10MG+MELATONIN-3MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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ZOLPIDEM-10MG+MELATONIN-3MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Taking caffeine with Zolsoma 10 Tablet 10's may increase the blood levels and effects of Zolsoma 10 Tablet 10's. Avoid taking excessive caffeine consumption while being treated with Zolsoma 10 Tablet 10's.

Diet & Lifestyle Advise

  • Do regular exercise during day time.
  • Do not take a nap during day time. Set regular timings to go to bed and wake up.
  • Relax at least 1 hour before bedtime by bathing with warm water, listening to music, or reading a book.
  • Make the bedroom dark and quiet, and ensure that your pillows and mattresses are comfortable.
  • Avoid watching tv, using mobiles or laptops just before bedtime.
  • Limit caffeine intake, including tea, coffee, hot chocolate, cola, and energy drinks, as it may reduce the effectiveness of Zolsoma 10 Tablet .
  • Avoid alcohol consumption as it may increase the risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleepwalking, or sleep-driving.

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Zolsoma 10 Tablet Substitute

Substitutes safety advice
  • Zolcalm-10 Tablet 10's

    9.54per tablet
  • Lexa Tablet 10's

    by AYUR

    7.61per tablet
  • Napq Plus 10 Tablet 10's

    9.90per tablet
  • Zolpirest-M Tablet 10's

    10.04per tablet
  • Zolprate M-10 Tablet 10's

    10.60per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Zolsoma 10 Tablet as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process, and reduced physical movements), sleepwalking, or sleep-driving.

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Pregnancy

Unsafe

Zolsoma 10 Tablet contains Zolpidem, a Category C pregnancy drug, and is not recommended for use during pregnancy as it may cause adverse effects in the baby after birth.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Zolsoma 10 Tablet as it may be excreted in breast milk.

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Driving

Unsafe

You may experience dizziness, drowsiness, confusion, decreased alertness, blurred, or double vision, especially the day after taking Zolsoma 10 Tablet . Therefore, avoid driving if you feel drowsy or dizzy after taking Zolsoma 10 Tablet .

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Liver

Caution

Take Zolsoma 10 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zolsoma 10 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Zolsoma 10 Tablet is not recommended for children below 18 years of age.

FAQs

Zolsoma 10 Tablet is used in the treatment of insomnia.
Zolsoma 10 Tablet is a sleeping pill used to treat insomnia (difficulty in falling or staying asleep). Zolpidem increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) that is involved in inducing sleep. Melatonin is a natural hormone that helps to maintain the normal sleep cycle (waking up and falling asleep)
No, Zolsoma 10 Tablet is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have a history of depression, please inform your doctor before taking Zolsoma 10 Tablet .
You are recommended to take Zolsoma 10 Tablet just before bedtime as it helps to sleep quickly and improves sleep quality. If you forget to take Zolsoma 10 Tablet at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.
No, you are not recommended to take Zolsoma 10 Tablet with hydrocodone or other opioid pain killers such as oxycodone, naloxone, and tramadol as co-administration of these medicines with Zolsoma 10 Tablet may increase the risk of difficulty in breathing, drowsiness, coma, and even death. However, before using Zolsoma 10 Tablet with any other medicines, you are advised to contact your doctor so that the dose may be adjusted to use safely.
Yes, Zolsoma 10 Tablet may cause dependence (mental and physical effects caused due to compulsion of taking Zolsoma 10 Tablet ) if used in high doses and for a prolonged time. This risk of dependency on Zolsoma 10 Tablet increases in patients who have a history of drug or alcohol abuse.

Country of origin

INDIA

Manufacturer/Marketer address

4F10, Ballad Estates, Tarnaka, Hyderabad - 500017, TS, India.
Other Info - ZOL0009

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