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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:20 PM IST
Zolnap-XR 6.25 mg Tablet is used in the short-term treatment of insomnia. It contains Zolpidem which relaxes muscles, reduces anxiety, and helps to fall asleep. Some people may experience dizziness, diarrhoea, drowsiness, headache, nausea, vomiting, nose or throat infections, tiredness, stomach pain, double vision, and back pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

ZOLPIDEM-6.25MG

Manufacturer/Marketer

Icon Life Sciences

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zolnap-XR 6.25 mg Tablet

Zolnap-XR 6.25 mg Tablet belongs to a class of drugs called 'sedative-hypnotics' primarily used in the short-term treatment of insomnia. Insomnia is a disorder of sleep that causes difficulty in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature due to various complications like stress, anxiety, and breathing problems.

Zolnap-XR 6.25 mg Tablet contains Zolpidem which works by increasing the activity of GABA, which is a chemical messenger in the brain acting as a natural nerve-calming agent, thereby inducing sleep. Thus, Zolnap-XR 6.25 mg Tablet relaxes muscles, reduces anxiety, and helps to fall asleep.

Take Zolnap-XR 6.25 mg Tablet as prescribed. Your doctor will advise you how often you take Zolnap-XR 6.25 mg Tablet based on your medical condition. Some people may experience dizziness, diarrhoea, drowsiness, headache, nausea, vomiting, nose or throat infections, tiredness, stomach pain, double vision, and back pain. Most of these side effects of Zolnap-XR 6.25 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zolnap-XR 6.25 mg Tablet or any other medicines, please tell your doctor. If you notice that the effect of tablets is not as well as at the beginning of the treatment, please consult a doctor as you might have developed tolerance to Zolnap-XR 6.25 mg Tablet and dose adjustment may be required. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Zolnap-XR 6.25 mg Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a serious condition where breathing stops and repeatedly starts in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Zolnap-XR 6.25 mg Tablet .

Uses of Zolnap-XR 6.25 mg Tablet

Treatment of Insomnia (sleeplessness)

Medicinal Benefits

Zolnap-XR 6.25 mg Tablet is a sleeping pill used in the short-term treatment of insomnia (difficulty in falling or staying asleep). Zolnap-XR 6.25 mg Tablet increases the activity of GABA (a chemical messenger in brain that acts as natural nerve-calming agent) that is involved in inducing sleep. Thus, Zolnap-XR 6.25 mg Tablet relaxes muscles, reduces anxiety and helps to fall asleep. Appropriate life style changes are recommended along with Zolnap-XR 6.25 mg Tablet to improve the quality of sleep.

Directions for Use

Take Zolnap-XR 6.25 mg Tablet on empty stomach for effective results or as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zolnap-XR 6.25 mg Tablet

  • Dizziness

  • Diarrhoea

  • Drowsiness

  • Headache

  • Nausea

  • Vomiting

  • Nose or throat infections

  • Tiredness

  • Stomach pain

  • Double vision

  • Back pain

Drug Warnings

If you notice that the tablets are not working as well as they did at the beginning of the treatment, please consult a doctor as you might have developed tolerance to Zolnap-XR 6.25 mg Tablet and dose adjustment may be required. Zolnap-XR 6.25 mg Tablet is a category C pregnancy drug and is not recommended for use during pregnancy as it may cause adverse effects on the baby after birth. If you are a breastfeeding mother, it is advised to consult a doctor before using Zolnap-XR 6.25 mg Tablet . If you have kidney, liver, or breathing problems, severe muscle weakness, sleep apnoea (a severe condition in which breathing stops and starts repeatedly in sleep), and if you have a history of depression or mental illness, please inform your doctor before taking Zolnap-XR 6.25 mg Tablet . Maintain a time gap of a minimum of 8 hours between taking Zolnap-XR 6.25 mg Tablet and driving to reduce the risk of increased adverse effects.

Drug Interactions

Drug-Drug Interaction: Zolnap-XR 6.25 mg Tablet may have interaction with high blood pressure-lowering medicines (metoprolol), opioid pain killers (hydrocodone, oxycodone, naloxone, tramadol), antidepressants (sertraline, desipramine, fluoxetine, venlafaxine, bupropion, fluvoxamine, escitalopram, amitriptyline, citalopram, duloxetine, mirtazapine), antibiotics (ciprofloxacin, rifampicin), antifungal drugs (ketoconazole), anti-anxiety drugs (alprazolam, clonazepam, lorazepam), antiallergics/antihistamines (diphenhydramine, hydroxyzine), muscle relaxants (cyclobenzaprine), and antiepileptic drugs (gabapentin, pregabalin).

Drug-Food Interaction: Zolnap-XR 6.25 mg Tablet may interact with caffeine, St John’s wort (herbal medicine for treating depression), and may reduce the effectiveness of Zolnap-XR 6.25 mg Tablet . Also, avoid alcohol intake as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process and reduced physical movements), sleepwalking, or sleep-driving.

Drug-Disease Interaction: Do not take Zolnap-XR 6.25 mg Tablet if you have severe liver disease, breathing problems, sleep apnoea (sudden stopping of breathing during sleep), severe muscle weakness, kidney problems, and any history of depression or mental illness.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • OXYCODONE
  • NALOXONE
  • TRAMADOL
  • SERTRALINE
  • AMITRIPTYLINE
  • DIPHENHYDRAMINE
  • CITALOPRAM
  • CLONAZEPAM
  • DULOXETINE
  • FLUOXETINE
  • GABAPENTIN
  • HYDROXYZINE
  • ESCITALOPRAM
  • LORAZEPAM
  • PREGABALIN
  • MIRTAZAPINE
  • ALPRAZOLAM
  • CYCLOBENZAPRINE
  • HYDROCODONE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Do regular exercise during day time.

  • Do not take nap during day time. Set regular timings to go to bed and wake up.

  • Relax yourself at least 1 hour before bedtime by taking a bath with warm water, listening to music or reading a book.

  • Make the bedroom dark and quiet and ensure that your pillows and mattresses are comfortable.

  • Avoid watching tv, using mobiles or laptops just before bedtime.

  • Limit caffeine intake including tea, coffee, hot chocolate, cola and energy drinks as it may reduce the effectiveness of Zolnap-XR 6.25 mg Tablet .

  • Avoid consumption of alcohol as it may increase risk of psychomotor impairment (slowdown of thought process and reduced physical movements), dependence, sleep walking or sleep driving.

Special Advise

  • You are advised to take Zolnap-XR 6.25 mg Tablet on empty stomach as taking Zolnap-XR 6.25 mg Tablet with food may reduce the effect of Zolnap-XR 6.25 mg Tablet .

  • If you are depressed or have had depression in the past, please inform your doctor before taking Zolnap-XR 6.25 mg Tablet as it may increase self-harming or suicidal thoughts.

  • If you notice any behavioral side effects such as delusions (false belief), nightmares, irritability, restlessness, aggressiveness, or hallucinations (hear, feel or see things that are actually not present), please contact your doctor.

  • If you are allergic to any sugars, inform your doctor as Zolnap-XR 6.25 mg Tablet contains lactose.

Disease/Condition Glossary

Insomnia: It is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to few weeks and occurs due to stress or changes in life. Chronic insomnia may last from more than 3 nights per week to more than 3 months. Insomnia is mostly caused due to depression, stress, anxiety, jet lag, shift work, uncomfortable beds, chronic illness, caffeine, nicotine or alcohol intake or due to certain medicines. It may be treated using sleeping pills, behaviour therapy, changes in sleep habits, identifying and treating chronic conditions.

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Alcohol

Unsafe

Avoid consumption of alcohol with Zolnap-XR 6.25 mg Tablet as it may increase the risk of dependence, psychomotor impairment (slowdown of thought process and reduced physical movements), sleep walking or sleep driving.

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Pregnancy

Unsafe

Zolnap-XR 6.25 mg Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy as it may cause adverse effects in baby after birth.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Zolnap-XR 6.25 mg Tablet as it may be excreted in breast milk.

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Driving

Unsafe

You may experience dizziness, drowsiness, confusion, decreased alertness, blurred or double vision especially the day after taking Zolnap-XR 6.25 mg Tablet . Therefore, avoid driving if you feel drowsy or dizzy after taking Zolnap-XR 6.25 mg Tablet .

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Liver

Caution

Take Zolnap-XR 6.25 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Zolnap-XR 6.25 mg Tablet is not recommended for severe liver disease patients.

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Kidney

Caution

Take Zolnap-XR 6.25 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Zolnap-XR 6.25 mg Tablet is not recommended for children below 18 years of age.

Country of origin

India

Manufacturer/Marketer address

Plot No. 128-B, Phase 1 & 2 G.I.D.C., Naroda, Ahmedabad - 382330. (Gujarat)
Other Info - ZOL0221

Author Details

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FAQs

Zolnap-XR 6.25 mg Tablet is used in the short-term treatment of insomnia.
No, you are not recommended to take Zolnap-XR 6.25 mg Tablet with hydrocodone or other opioid pain killers such as oxycodone, naloxone and tramadol as co-administration of these medicines with Zolnap-XR 6.25 mg Tablet may increase the risk of difficulty in breathing, drowsiness, coma and even death. However, before using Zolnap-XR 6.25 mg Tablet with any other medicines, you are advised to contact your doctor so that the dose may adjusted to use safely.
You are recommended to take Zolnap-XR 6.25 mg Tablet just before bedtime as it helps to sleep quickly and improve the quality of sleep. If you forget to take Zolnap-XR 6.25 mg Tablet at night, do not take it in the day time as it may cause drowsiness, confusion and dizziness.
No, Zolnap-XR 6.25 mg Tablet is not recommended for depression patients as it may worsen the condition and increase self-harming or suicidal thoughts. Therefore, if you are suffering from depression or have history of depression, please inform your doctor before taking Zolnap-XR 6.25 mg Tablet .
No, Zolnap-XR 6.25 mg Tablet is not recommended for use during pregnancy especially in the third trimester and during delivery as it may cause adverse effects such as breathing problems, low body temperature, floppy muscle and withdrawal symptoms in baby after birth due to physical dependence.
Yes, Zolnap-XR 6.25 mg Tablet may cause dependence (mental and physical effects caused due to compulsion of taking Zolnap-XR 6.25 mg Tablet ) if used in high doses and for prolonged time. This risk of dependency on Zolnap-XR 6.25 mg Tablet increases in patients who have a history of drug or alcohol abuse.
Zolnap-XR 6.25 mg Tablet helps you sleep better by increasing the activity of a chemical in your brain called GABA (Gamma-aminobutyric acid). This chemical calms your nerves and makes you feel relaxed, which helps you fall asleep. It also relaxes your muscles and reduces feelings of anxiety.
The common side effects of Zolnap-XR 6.25 mg Tablet include dizziness, diarrhoea, drowsiness, headache, nausea, vomiting, nose or throat infections, tiredness, stomach pain, double vision, and back pain. Most of these side effects are mild and usually resolve on their own. However, if the side effects persist or worsen, please consult your doctor.
Zolnap-XR 6.25 mg Tablet can cause sedation (state of sleepiness) and relaxation. Some people might misuse it in an attempt to get high from its sedative effects, so it is important to take Zolnap-XR 6.25 mg Tablet only as prescribed by your doctor.
Yes, Zolnap-XR 6.25 mg Tablet can be abused, especially if taken in higher doses or without a prescription from your doctor. This is more commonly seen in people with a history of drug abuse and alcohol consumption. Therefore, Zolnap-XR 6.25 mg Tablet should be taken only as prescribed by the doctor.
While there might not be direct drug-drug interactions between Zolnap-XR 6.25 mg Tablet and prednisone, both can affect your central nervous system. Please consult your doctor before taking Zolnap-XR 6.25 mg Tablet with prednisone.
Zolnap-XR 6.25 mg Tablet is mainly used to treat insomnia (difficulty falling asleep) and isn’t usually prescribed for anxiety (feelings of fear and uneasiness). While Zolnap-XR 6.25 mg Tablet can have a calming effect that might temporarily ease anxiety, it’s not considered a suitable long-term solution for anxiety disorders. Consult the doctor for appropriate treatment.
The symptoms of Zolnap-XR 6.25 mg Tablet overdose include confusion, somnolence (drowsiness), problems with breathing or heart function, and in severe cases, coma (a prolonged loss of consciousness). If you take too much Zolnap-XR 6.25 mg Tablet , call your doctor right away or seek emergency treatment.
You should avoid drinking alcohol while taking Zolnap-XR 6.25 mg Tablet , as it may increase the risk of psychomotor impairment (slowdown of thought processes and reduced physical movements), dependence, sleepwalking, or sleep driving. Avoid the intake of caffeine and St John’s wort (herbal medicine for treating depression), as they can make the medication less effective. If you feel dizzy, drowsy, confused, or have blurred vision after taking Zolnap-XR 6.25 mg Tablet , please avoid driving or using machines.
You should not take Zolnap-XR 6.25 mg Tablet if you are allergic to any of its ingredients. Zolnap-XR 6.25 mg Tablet is classified as a Category C pregnancy drug and is not recommended for use during pregnancy. If you are a breastfeeding mother, please avoid taking Zolnap-XR 6.25 mg Tablet , as it may be excreted in breast milk. If you have kidney or liver problems, breathing issues, severe muscle weakness, sleep apnea (a condition in which breathing stops and starts repeatedly during sleep), or a history of depression or mental illness, please consult your doctor before taking Zolnap-XR 6.25 mg Tablet .
No, you should not take Zolnap-XR 6.25 mg Tablet with food or immediately after a meal, as doing so may reduce its effectiveness. It will work faster if you take Zolnap-XR 6.25 mg Tablet on an empty stomach.
Zolnap-XR 6.25 mg Tablet should be taken as prescribed by a healthcare provider. It should only be used for a short term (usually 2-4 weeks) to treat insomnia (difficulty falling asleep) because your body gets used to this medicine quickly, which may lead to dependence (addiction to the drug).
Yes, Zolnap-XR 6.25 mg Tablet can cause dry mouth as a common side effect. This occurs because it affects neurotransmitters in the brain that influence saliva production. Regarding weight, Zolnap-XR 6.25 mg Tablet is not directly linked to significant weight gain or loss, but some people may experience changes in appetite that could indirectly affect their weight. If you have concerns about these side effects, discuss them with your doctor.
Zolnap-XR 6.25 mg Tablet generally starts working within 30 minutes after taking it. It is usually recommended to take it right before you plan to sleep.
Do not stop taking Zolnap-XR 6.25 mg Tablet without consulting your doctor, especially if you have taken it for longer than two weeks. If you suddenly stop taking Zolnap-XR 6.25 mg Tablet , you may experience withdrawal symptoms such as shakiness, lightheadedness, stomach and muscle cramps, nausea, vomiting, sweating, tiredness, uncontrollable crying, nervousness, panic attacks, difficulty falling asleep or staying asleep, uncontrollable shaking of a part of your body, and, rarely, seizures. The doctor will reduce the dose gradually to prevent withdrawal symptoms.
To improve your sleep without medication, establish a consistent sleep schedule by going to bed and waking up at the same time each day. Create a relaxing bedtime routine, limit screen time before sleep, and make sure your sleep environment is dark, cool, and quiet. Regular exercise during the day can also help promote better sleep. Avoid caffeine, cigarettes, alcohol, heavy meals, and exercise for a few hours before bedtime.
Insomnia is a disorder of sleep associated with problems in falling asleep or staying asleep. It may be acute (short-term) or chronic (long-term) in nature. Acute insomnia may last from one night to a few weeks and occurs due to stress or changes in life. Chronic insomnia may last from more than 3 nights per week to more than 3 months.
Insomnia is mostly caused by depression, stress, anxiety, jet lag, shift work, uncomfortable sleeping conditions, chronic illness, certain medications, and the intake of substances like caffeine, nicotine, or alcohol.

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