Zolfrac Infusion 100 ml
₹3128.3*
MRP ₹3815
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₹3243*
MRP ₹3815
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Zolfrac Infusion belongs to the class of medicines called 'bisphosphonates' used to treat osteoporosis (weak and brittle bones) caused by menopause or long-term steroid use. Zolfrac Infusion also treats Paget’s bone and high calcium levels caused by cancer. Osteoporosis is a bone disease that weakens and thins bones by decreasing bone density, common in post-menopausal women. As the density of bones decreases, they weaken and are more likely to break.
Zolfrac Infusion contains Zoledronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cell that destroys bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking.
A doctor or nurse will administer Zolfrac Infusion . In some cases, you may experience headache, fever, nausea, dizziness, vomiting, back pain, diarrhea, pain in the muscles, joints, or bones, swelling, or pain at the infusion site. Most of these side effects of Zolfrac Infusion do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Zolfrac Infusion or any other medicines, please tell your doctor. Avoid taking Zolfrac Infusion if you are pregnant or breastfeeding and consult a doctor. Zolfrac Infusion is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Zolfrac Infusion if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Zolfrac Infusion may cause dizziness. Zolfrac Infusion may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.
Zolfrac Infusion contains Zoledronic acid used to treat postmenopausal osteoporosis, Paget’s disease, and hypercalcemia of malignancy (bone cancer in which excess of calcium exits). Zolfrac Infusion binds to the bone tightly and prevents calcium removal by osteoclasts (a type of bone cell that destroy bone tissue). This prevents osteoclasts from breaking down the bone, strengthening bones, and minimizing the risk of bones breaking. Also, Zolfrac Infusion may reduce calcium levels in the blood by preventing calcium reabsorption from bones to the blood. Thus, it helps in treating high calcium levels in the blood caused by cancer.
If you are allergic to Zolfrac Infusion or any other medicines, please tell your doctor. Avoid taking Zolfrac Infusion if you are pregnant or breastfeeding and consult a doctor. Zolfrac Infusion is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Zolfrac Infusion if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Zolfrac Infusion may cause dizziness. If you are not able to take daily calcium supplements, have had sections of the intestine or some or all of the parathyroid glands in the neck surgically removed, have cancer, gum disease, poor dental health, or planned tooth extraction or kidney problem, inform your doctor before taking Zolfrac Infusion . If you are a smoker, inform your doctor before receiving Zolfrac Infusion as it may increase the risk of dental problems. Zolfrac Infusion may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw. You are recommended to drink at least 2 glasses of fluids before and after treatment with Zolfrac Infusion as advised by your doctor to prevent dehydration. Take calcium and vitamin D supplements as prescribed by your doctor as Zolfrac Infusion may reduce calcium levels in the blood.
Drug-Drug Interaction: Zolfrac Infusion may interact with antibiotics (gentamicin) and water pills (furosemide).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Avoid taking Zolfrac Infusion if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. If you have cancer, gum disease, poor dental health, or planned tooth extraction or kidney problem, inform your doctor before taking Zolfrac Infusion .
Osteoporosis: It is a bone disease that weakens and thins bones by decreasing bone density. As the density of bones decreases, they weaken and are more likely to break. Post-menopausal women are more likely to develop osteoporosis than men because, at menopause, women’s ovaries stop producing estrogen (a female hormone) essential to keeping bones healthy. Following menopause, bone loss occurs, making bones weak and more likely to break. Also, long-term use of steroids may affect bone strength and cause osteoporosis in both men and women. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, and a bone that breaks much more easily than expected.
Paget’s disease: In Paget’s disease, bone remodeling (removal of old bone and replacement with new bone material) is too quick, and new bone is formed in a disordered manner making it weaker than normal. If left untreated, the bone may become deformed, painful, and broken.
Alcohol
Caution
Interaction of alcohol with Zolfrac Infusion is unknown. Please consult a doctor before consuming alcohol with Zolfrac Infusion .
Pregnancy
Unsafe
Zolfrac Infusion is a category D pregnancy drug and is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant.
Breast Feeding
Unsafe
Zolfrac Infusion is contraindicated in breastfeeding mothers. Therefore, please consult a doctor if you are breastfeeding.
Driving
Caution
Zolfrac Infusion may cause dizziness. Therefore, avoid driving or operating machinery if you feel dizzy after taking Zolfrac Infusion .
Liver
Caution
Take Zolfrac Infusion with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Caution
Take Zolfrac Infusion with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Zolfrac Infusion if you have severe kidney problems.
Children
Unsafe
Zolfrac Infusion is not recommended for children below 18 years as the safety and effectiveness were not established.
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