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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:50 PM IST

Zivagest Tablet 10's is used in the treatment of disorders like dysmenorrhea, endometriosis, infertility, irregular menstrual cycles, and premenstrual syndrome that are linked to progesterone deficiency. It can be used in conjunction with estrogen for hormone replacement therapy or in the treatment of dysfunctional bleeding or secondary amenorrhea. It contains Dydrogesterone, which is a female hormone that controls women's ovulation and menstruation. It causes secretive changes in the uterus's endometrium lining, promotes the breast's development, relaxes the uterus, blocks the maturation and release of the follicle, and retains pregnancy. It may cause side effects such as breast tenderness, swelling in other parts of the body, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding.

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Prescription drug

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Composition :

DYDROGESTERONE-10MG

Manufacturer/Marketer :

Orziva Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Zivagest Tablet 10's

Zivagest Tablet 10's is used in the treatment of disorders like dysmenorrhea, endometriosis, infertility, irregular menstrual cycles, and premenstrual syndrome that are linked to progesterone deficiency. Zivagest Tablet 10's can be used in conjunction with estrogen for hormone replacement therapy or in the treatment of dysfunctional bleeding or secondary amenorrhea. Infertility is the inability to conceive within 12 months. On the other hand, Premenstrual syndrome comprises signs and symptoms like mood swings, tender breasts, food cravings, fatigue, irritability, and depression. It occurs during certain days of the menstrual period in females, generally just before their menses.

Zivagest Tablet 10's is a female hormone that controls women's ovulation and menstruation. Zivagest Tablet 10's causes secretive changes in the uterus's endometrium lining, promotes the breast's development, relaxes the uterus, blocks the maturation and release of the follicle, and retains pregnancy.

Your doctor will advise you on your dose and how often you need to take this medication based on your medical condition. While using this medicine, you may sometimes have breast tenderness, swelling in other parts of the body, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding. Most of these side effects of Zivagest Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Using Zivagest Tablet 10's may increase the risk of blood clots. Make sure that before taking this medicine, you inform your doctor if you have had breast cancer, unusual bleeding in the vagina, liver disease, or any other health problems. If you are taking any other medicine or are allergic to any medication, please inform your doctor. Avoid smoking and alcohol to prevent any unpleasant side effects. Zivagest Tablet 10's should not be used if you have heart disease or dementia because this medicine may increase your risk of developing these conditions.

Uses of Zivagest Tablet 10's

Treatment of Infertility, Prevention of miscarriages, Dysfunctional uterine bleeding, Irregular menses cycle, Dysmenorrhoea (painful periods), Endometriosis (A disorder in which tissue that normally lines the uterus grows outside the uterus), Treatment of threatened and habitual abortion associated with proven progesterone deficiency.

Directions for Use

Zivagest Tablet 10's should be swallowed as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Zivagest Tablet 10's is a female hormone that regulates ovulation and menstruation in women. It helps maintain a healthy womb lining during the pregnancy stage. Zivagest Tablet 10's helps initiate the menses cycle (periods) in women who have not yet reached menopause. Besides this, it prevents overgrowth of the uterus in postmenopausal women who take estrogen as hormone replacement therapy (HRT). Zivagest Tablet 10's is used to regulate the uterine lining in postmenopausal women receiving estrogens who have not removed their uterus through surgery. It also helps treat amenorrhea (cessation or irregular menses cycle for more than three months). It is also given in combination with estrogens as part of menopausal replacement therapy. The injection form of Zivagest Tablet 10's is prescribed for treating abnormal uterine bleeding along with irregular or ceased menstrual cycles. The intravaginal gel form of Zivagest Tablet 10's assists in reproductive technology for infertile women with progesterone deficiency or irregular or ceased menstrual cycle. The vaginal insert form of Zivagest Tablet 10's supports early pregnancy and implantation of an embryo in the uterus. Off-label use of Zivagest Tablet 10's helps in reducing the risk of preterm birth.

How Zivagest Tablet 10's Works

Zivagest Tablet 10's is a female hormone that controls women's ovulation and menstruation. Zivagest Tablet 10's causes secretive changes in the uterus's endometrium lining, promotes the breast's development, relaxes the uterus, blocks the maturation and release of the follicle, and retains pregnancy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zivagest Tablet 10's

  • Abdominal pain
  • Bloating
  • Headache
  • Dizziness
  • Depression
  • Breast tenderness
  • Hot flushes
  • Vaginal discharge
  • Joint pain
  • Urinary problems
  • Nausea
  • Fatigue or extreme tiredness
  • Somnolence or sleepiness
  • Vaginal haemorrhage
  • Pruritus (severe itching of the skin)

What if I have taken an overdose of Zivagest Tablet 10's

Do not take more than the prescribed dose of Zivagest Tablet 10's as it may cause overdose. The symptoms of overdose include vomiting, nausea, dizziness and lack of energy. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Zivagest Tablet 10's with estrogens should not be used to prevent heart disease, heart attacks, strokes, or dementia. Using Zivagest Tablet 10's with estrogens may increase the chance of getting heart attacks, strokes, breast cancer, and blood clots. In some cases, using Zivagest Tablet 10's with estrogen may produce dementia among women aged 65 and older. Do not use Zivagest Tablet 10's if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using the Zivagest Tablet 10's if you have had a heart attack, stroke, blood clot, liver problems, kidney problems, pregnant, breastfeeding or planning to get pregnant, asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, heart problems, thyroid, or have high calcium levels in your blood. Use caution while driving a motor vehicle, as dizziness or drowsiness may occur. If you are using Zivagest Tablet 10's before any lab tests or biopsies, tell your doctor about this, as it can affect the report values. Patients with rare hereditary problems like galactose intolerance, lactase deficiency or glucose-galactose malabsorption should not take the Zivagest Tablet 10's.

Diet & Lifestyle Advise

  • Regular exercise and physical activity can minimize hot flushes and improve sleep. Weight-bearing exercises can also help strengthen bones. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take a minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Zivagest Tablet 10's Substitute

Substitutes safety advice
  • Duphaston 10 mg Tablet 10's

    82.13per tablet
  • Dydrogest 10 Tablet 10's

    64.85per tablet
  • Dydroboon Tablet 10's

    by AYUR

    58.41per tablet
  • Dydrofem 10 mg Tablet 10's

    by AYUR

    63.00per tablet
  • Isofit Tablet 10's

    53.91per tablet
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Alcohol

Caution

You are recommended not to consume alcohol along with Zivagest Tablet 10's to avoid unpleasant side effects.

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Pregnancy

Safe if prescribed

Zivagest Tablet 10's can be safely used in pregnant women. Your doctor will weigh the benefits and potential risks before prescribing them. If you have any concerns regarding this, discuss them with the doctor.

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Breast Feeding

Caution

Zivagest Tablet 10's should be used in breastfeeding mothers only if the benefits outweigh the risks. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Driving

Caution

It is advised to drive with caution after taking Zivagest Tablet 10's as it may interfere with driving capabilities. It can make you feel drowsy.

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Liver

Caution

Limited information was available for the use of Zivagest Tablet 10's in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using Zivagest Tablet 10's in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available for the use of Zivagest Tablet 10's in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using Zivagest Tablet 10's in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Zivagest Tablet 10's is not recommended for children below 12 years of age.

FAQs

Zivagest Tablet 10's is used in the treatment of infertility, prevention of miscarriages, dysfunctional uterine bleeding, irregular menses cycle, dysmenorrhoea (painful periods), endometriosis (a disorder in which tissue that normally lines the uterus grows outside the uterus), threatened and habitual abortion associated with proven progesterone deficiency.
Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high levels of estrogen, and women can have decreased sex drive (libido), weight gain, or gallbladder problems.
Yes, Zivagest Tablet 10's might cause ovarian cysts. These are small fluid-filled sacs that can occur on ovaries. These are harmless. They disappear without treatment.
Zivagest Tablet 10's helps in preparing the endometrium potential for pregnancy after ovulation. It thickens the lining of the endometrium to accept a fertilized egg. It also prevents muscle contractions of the uterus that would reject an egg in the uterus. So, if the body has a high progesterone level, ovulation will not occur then.
Yes, Zivagest Tablet 10's may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking Zivagest Tablet 10's, please consult your doctor.
Yes, Zivagest Tablet 10's can be taken every day. This medicine is prescribed once daily, preferably in the evening or at bedtime. Please take it in the dose and duration as advised by the doctor.
Yes, Zivagest Tablet 10's is used to prevent habitual miscarriage and regular abortion. Your doctor will decide whether you should continue or stop taking Zivagest Tablet 10's. Do not take medication of your own or self-medicate.
Yes, Zivagest Tablet 10's is synthetic or man-made progesterone, which is very similar to progesterone made by your body. It is taken in various gynaecological problems when your body is unable to make a sufficient amount of natural progesterone.
The most common side effects of Zivagest Tablet 10's are migraines/headaches, nausea, menstrual disorders and breast pain/tenderness.
There is no clinical evidence that Zivagest Tablet 10's decreases fertility at therapeutic doses. However, taking it only after consulting any obstetrician/gynaecologist is better.
Zivagest Tablet 10's should be taken for the duration prescribed by the doctor. The dose and duration will depend upon your condition and response to treatment. Talk to your doctor if you have any concerns.
In some cases, Zivagest Tablet 10's may increase the risk of birth defects such as hypospadias (the opening of the urethra is not located at the tip of the penis) and congenital heart defects.
Dydrogesterone is a synthetic form of progesterone. Dydrogesterone is used in conditions when the body does not make enough progesterone.
Do not take Zivagest Tablet 10's if you are allergic to any of its components, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or are undergoing oestrogen plus progestin treatment.
If you forget a dose, take the missed dose as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose.
Zivagest Tablet 10's may cause breast pain and tenderness as a side effect. Consult the doctor if the condition persists or worsens or if you notice any other changes in your breast such as a lump.

Country of origin

India

Manufacturer/Marketer address

Scf 511, 2nd Floor, Motor Market, Mani Majra, Chandigarh-160101, India
Other Info - ZIV0098

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