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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Zithrocin-500 Tablet is used to treat various bacterial infections such as respiratory system (like pneumonia, bronchitis, tonsillitis, pharyngitis and sinusitis), skin infections (like acne and rosacea), ear infections, and sexually transmitted infections. It contains Azithromycin, which stops the growth of bacteria. It may cause some common side effects such as diarrhoea, nausea, vomiting, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zithrocin-500 Tablet

Zithrocin-500 Tablet is an antibiotic. It is used to treat various bacterial infections such as respiratory system (like pneumonia, bronchitis, tonsillitis, pharyngitis and sinusitis), skin infections (like acne and rosacea), ear infections, and sexually transmitted infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly.

Zithrocin-500 Tablet slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival. Zithrocin-500 Tablet does not treat a viral infection like flu or a common cold.

Zithrocin-500 Tablet should only be taken if advised by your doctor. It can be taken with or without food but should be consumed at a fixed time for the best results. Zithrocin-500 Tablet should not be consumed more than the recommended dose, to avoid unpleasant side effects. Also, the course should be completed even if you feel better, as it is an antibiotic. Some common side effects of Zithrocin-500 Tablet are diarrhoea, nausea, vomiting, and indigestion. An allergic reaction such as rashes, itching, swelling, and shortness of breath can occur in rare cases. Please consult your doctor if an allergic reaction becomes severe.

Tell your doctor if you have liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). You should consult a doctor if you have had diarrhoea for more than four days. However, do not take any anti-diarrheal medicine until your doctor tells you. It is unknown whether Zithrocin-500 Tablet harms the baby or passes into breast milk during pregnancy and breastfeeding. Contacting a doctor before using Zithrocin-500 Tablet during pregnancy and while breastfeeding is better. Avoid too much exposure to sunlight as Zithrocin-500 Tablet can make your skin sensitive to sunburn. In this case, it is advisable to wear protective clothing or apply sunscreen (SPF 30 or higher) when you are outdoors.

Uses of Zithrocin-500 Tablet

Treatment of bacterial infections

Medicinal Benefits

Zithrocin-500 Tablet slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival. It prevents and treats bacterial infections like throat and sinus infections, chest infections (like bronchitis and pneumonia), ear infections, mouth and dental infections, eye infections, skin and tissue infections (like acne), and stomach and intestinal infections. It is better tolerated and has more effective tissue penetration than other similar antibiotics like erythromycin. Doctors prescribe Zithrocin-500 Tablet for people who are intolerant to penicillin antibiotics. Besides this, it also helps prevent infection following burns, surgery or dental procedures, sexually transmitted infections, bone infections or scarlet fever (bacterial illness with strep throat).

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zithrocin-500 Tablet

  • Diarrhoea

  • Feeling or being sick (nausea or vomiting)

  • Stomach cramps

  • Loss of appetite

  • Bloating

  • Indigestion

Drug Warnings

Tell your doctor if you have liver problems (jaundice), muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). In rare cases, the use of Zithrocin-500 Tablet can cause diarrhoea, so if you have watery or bloody diarrhoea, stop taking Zithrocin-500 Tablet and call your doctor. However, do not take any anti-diarrheal medicine until your doctor tells you. It is unknown whether Zithrocin-500 Tablet harms the baby during pregnancy. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding before using Zithrocin-500 Tablet. Do not take Zithrocin-500 Tablet if allergic to azithromycin or other macrolide antibiotics. Inform the doctor if you are using cholesterol-lowering drugs (statins like simvastatin, lovastatin etc.), anti-gout or anti-arthritis drugs (colchicine) and medicine for treating overactive bladder (tolterodine). Zithrocin-500 Tablet is not recommended for the patients with pneumonia who are judged to be inappropriate for oral therapy due to moderate to severe illness or risk factors.

Drug Interactions

Drug-Drug Interactions: Zithrocin-500 Tablet have interactions with anti-nausea pills (domperidone), mental health pills (pimozide, amisulpride), anti-migraine medicines (ergotamine, dihydroergotamine), anti-cholesterol pills (simvastatin), bladder weakness medicine (tolterodine) and anti-gout/arthritis medicine (colchicine). Taking these drugs with Zithrocin-500 Tablet may cause serious side effects.

Drug-Food Interactions: No relevant drug-food interaction found with Zithrocin-500 Tablet. As a precautionary measure, the consumption of alcoholic beverages should be avoided as it may lead to drowsiness and dizziness.

Drug-Disease Interactions: Zithrocin-500 Tablet should not be given to people with liver problems, muscle problem (myasthenia gravis), heart rhythm disorder (arrhythmia), electrolyte imbalance (low potassium or magnesium level) and colitis (inflammation of the intestine).

Drug-Drug Interactions Checker List

  • DOMPERIDONE
  • PIMOZIDE
  • AMISULPRIDE
  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • SIMVASTATIN
  • TOLTERODINE
  • COLCHICINE

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Zithrocin-500 Tablet to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.

  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Zithrocin-500 Tablet.

  • Avoid intake of alcoholic beverages with Zithrocin-500 Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Zithrocin-500 Tablet in fighting off infections.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms, commonly spherical, rod-shaped, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine can be more prone to bacterial infection.

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Alcohol

Safe if prescribed

Zithrocin-500 Tablet should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

There is insufficient information available about the use of Zithrocin-500 Tablet during pregnancy. Therefore you should not use Zithrocin-500 Tablet during pregnancy unless explicitly advised by your doctor.

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Breast Feeding

Unsafe

Zithrocin-500 Tablet is partially passed through the mother’s milk, therefore it should not be used if you are breastfeeding.

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Driving

Safe if prescribed

There are no data available about the influence of Zithrocin-500 Tablet on the ability to drive or operate machines. However, Zithrocin-500 Tablet may cause dizziness and seizures so make sure you are not affected before driving or operating machinery.

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Liver

Caution

You should tell your doctor if you have liver problems as your doctor may need to alter the normal dose.

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Kidney

Caution

You should tell your doctor if you have kidney problems as your doctor may need to alter the normal dose.

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Children

Caution

Safety and effectiveness in the treatment of patients under 6 months of age have not been established. So, it is not recommended for children less than 6 months of age. However, if the doctor has prescribed for the children more than 6 months Zithrocin-500 Tablet can be used.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ZIT0141

FAQs

Zithrocin-500 Tablet is used to treat bacterial infections such as respiratory tract infections (like pneumonia, bronchitis, tonsillitis, pharyngitis and sinusitis), skin infections (like acne and rosacea), ear infections, and sexually transmitted infections. It works by killing the harmful bacteria.
Do not take antacids that contain aluminium or magnesium hydroxide within 2 hours before or after you take Zithrocin-500 Tablet. These antacids can interact with Zithrocin-500 Tablet and make them less effective when taken at the same time.
Never stop the treatment with Zithrocin-500 Tablet on your own as the infection may come back again (relapse) if the prescribed treatment is not completely taken. Before stopping Zithrocin-500 Tablet once discuss this with your doctor.
If you forget to take Zithrocin-500 Tablet, take your dose as soon as possible. If it is almost time for the next dose, just skip that dose and take the next one when it is due. If in doubt, please contact your doctor. Do not take a double dose to make up for a forgotten dose
Zithrocin-500 Tablet can cause diarrhoea, which may be a sign of a new infection. If you have diarrhoea that is watery or bloody, call your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.
You should avoid taking Zithrocin-500 Tablet if you have colitis (intestine inflammation), heart rhythm disorder, liver disease (like jaundice), and muscle problem (like myasthenia gravis). Contact your doctor if you have these conditions before taking Zithrocin-500 Tablet.
No, it is a Schedule H drug that can be taken only if your doctor has prescribed it. Taking it on your own or self-medication can cause unwanted side-effects and lead to antibiotic resistance thereby lowering its efficiency.
Yes in some cases, people using Zithrocin-500 Tablet may get a fungal skin infection known as thrush. It happens because Zithrocin-500 Tablet also kills harmless bacteria that protects against thrush.
Zithrocin-500 Tablet is an effective antibiotic that helps treat bacterial infections. It has a broad spectrum of anti-bacterial activity and is effective against gram-positive and gram-negative bacteria.
Zithrocin-500 Tablet can be taken with or without food.
Zithrocin-500 Tablet should be used with caution in patients with liver problems. In some cases, the use of Zithrocin-500 Tablet can cause diarrhoea, so if you have watery or bloody diarrhoea, stop taking Zithrocin-500 Tablet and call your doctor.
Zithrocin-500 Tablet may interact with anti-emetics, neuroleptics, migraine medicines, statins, anticholinergics and anti-gout medicines. Before starting Zithrocin-500 Tablet, let the doctor know if you are taking any other medicines to prevent interactions.
Store Zithrocin-500 Tablet at room temperature, in a cool and dry place. Keep it out of sight and reach of children.
Side effects of Zithrocin-500 Tablet include diarrhoea, nausea, vomiting, and indigestion. Please consult the doctor if any of the side effects persist or worsen.

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