Zilsar 40 Tablet belongs to a group of medications called 'anti-hypertensives' primarily used to treat high blood pressure (hypertension). High blood pressure is a chronic (long-term) condition in which blood pressure is elevated persistently in higher than normal levels. If left untreated, this condition can increase the risk of heart-related diseases like heart attack, heart failure, stroke, and irregular heartbeat, and leads to other complications.

Zilsar 40 Tablet contains ‘Azilsartan medoxomil’, is an angiotensin-II receptor antagonist (AIIRAs), which narrows and relaxes the constricted blood vessels increasing the blood pressure; therefore, blocking angiotensin can result in widening of the narrowed blood vessels. This effect allows the blood to flow more smoothly in the blood vessels.

Take Zilsar 40 Tablet with or without food or as directed by your doctor. The doctor determines the dose and duration of the medicine. Swallow the tablet as a whole with a glass of water. Do not crush, chew, or break it. The common side-effects of Zilsar 40 Tablet are dizziness, diarrhoea, low blood pressure, nausea, muscle spasms, skin rash, and itching. Consult your doctor immediately if you experience severe diarrhoea, considerable weight loss, or other unwanted effects.

Do not take Zilsar 40 Tablet if you are allergic to ‘azilsartan medoxomil’ or any ingredients present in it. A Zilsar 40 Tablet should not be used in pregnant women who are more than 3 months pregnant, patients with diabetes or kidney failure, and do not use blood pressure-lowering medicine containing aliskiren. Inform your doctor if you are taking potassium supplements or any other prescription or non-prescription drugs. Zilsar 40 Tablet is not recommended for children and adolescents under 18 years of age.

Zilsar 40 Tablet contains ‘Azilsartan medoxomil’ which belongs to the class of ‘antihypertensives’. It is primarily used to reduce high blood pressure. It is an angiotensin-II receptor blocker (ARB) that blocks the hormone angiotensin. Angiotensin narrows the blood vessels increasing the blood pressure; therefore blocking angiotensin can widen the narrowed blood vessels. This effect allows the blood to flow more smoothly in the blood vessels and lower blood pressure.

• Dizziness
• Diarrhoea
• Low blood pressure
• Nausea
• Muscle spasms

Do not take Zilsar 40 Tablet if you are allergic to ‘azilsartan medoxomil’ or any other ingredients present in it. Inform your doctor if you have liver disease, heart problems, diabetes, or kidney problems, and taking blood pressure-lowering medication containing aliskiren. Also, inform your doctor if you are taking any prescription or non-prescription drugs and nutritional supplements. Take Zilsar 40 Tablet with caution if you have kidney, severe liver disease, have a disease of the adrenal gland called primary hyperaldosteronism, have raised potassium levels in the blood, or if you are on dialysis. During treatment, seek medical attention if you experience severe, persistent diarrhoea and substantial weight loss.

Drug-Drug Interactions: Zilsar 40 Tablet may interact with Lithium (a medicine for mental health problems), non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, diclofenac, heparin (a medicine for thinning the blood), diuretics (water tablets), Aliskiren or other medicines to lower your blood pressure (angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker, such as enalapril, lisinopril, ramipril or valsartan, telmisartan).

Drug-Food Interactions: Zilsar 40 Tablet may interact with high potassium-containing food and drinks. Also, alcohol should not be consumed while taking Zilsar 40 Tablet .

Drug-Disease Interactions: Zilsar 40 Tablet should be used with caution in patients with kidney problems, liver disease, heart failure, diabetes, hyperkalemia (increased potassium levels in the blood), and adrenal gland problems.

• LITHIUM
• IBUPROFEN
• DICLOFENAC
• HEPARIN
• ALISKIREN
• ENALAPRIL+HYDROCHLOROTHIAZIDE
• LISINOPRIL
• RAMIPRIL
• VALSARTAN
• TELMISARTAN

• Keep your weight under control with body mass index (BMI) 19.5-24.9.

• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

• Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

• Limit alcohol intake. One serving for women and two servings for men is advisable.

• Quit smoking as it is the best strategy to lower the risk of heart disease.

• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

• Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

• Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Your doctor may check your kidney function, blood pressure, and electrolyte levels in your blood at regular intervals while using Zilsar 40 Tablet .

Hypertension: It is a chronic (long-term) condition in which blood pressure is elevated persistently at higher than normal levels. It occurs when the blood’s force against the wall of blood vessels is too high. This condition can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes damage to the brain, kidneys, and eyes. The risk of high blood pressure complications increases with the following: obesity, smoking, diabetes, alcohol intake, lack of physical inactivity, stress, and kidney diseases.