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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
ZEKACIN 250MG INJECTION 2ML is used to treat bacterial infections. It contains Amikacin sulphate, which works by inhibiting the production of bacterial proteins which are necessary for the survival of the bacteria. Thereby, leads to the death of the bacterial cell. Thus, it helps treat bacterial infections. In some cases, you may experience certain common side effects such as irritation at the site of application, skin rash, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Synonym :

AMIKACIN

Manufacturer/Marketer :

Wockhardt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About ZEKACIN 250MG INJECTION 2ML

ZEKACIN 250MG INJECTION 2ML is used to treat bacterial infections. Bacterial infection can be defined as the proliferation/multiplication of harmful strains of bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.

ZEKACIN 250MG INJECTION 2ML works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. It kills the bacterial cell. Thus, ZEKACIN 250MG INJECTION 2ML helps treat bacterial infections.

ZEKACIN 250MG INJECTION 2ML will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side effects, such as irritation at the site of application, skin rash, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not be reluctant to speak with your doctor if you experience any difficulty while taking ZEKACIN 250MG INJECTION 2ML. Your doctor may advise you to get urine, blood, and hearing tests before and during the treatment to check for signs of side effects. Depending upon the results of these tests, your doctor may adjust the dose of ZEKACIN 250MG INJECTION 2ML. You are advised to be well hydrated before and during the treatment with ZEKACIN 250MG INJECTION 2ML.

Uses of ZEKACIN 250MG INJECTION 2ML

Treatment of Bacterial infections

Directions for Use

ZEKACIN 250MG INJECTION 2ML will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

ZEKACIN 250MG INJECTION 2ML belongs to the group of antibiotic medicines called aminoglycosides. ZEKACIN 250MG INJECTION 2ML is used to treat serious bacterial infections caused by bacteria. ZEKACIN 250MG INJECTION 2ML works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. This leads to the death of bacteria.

How ZEKACIN 250MG INJECTION 2ML Works

ZEKACIN 250MG INJECTION 2ML works by inhibiting the production of bacterial proteins, which are necessary for the survival of the bacteria. It kills the bacterial cell. Thus, ZEKACIN 250MG INJECTION 2ML helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ZEKACIN 250MG INJECTION 2ML

  • Irritation at the site of application
  • Skin rash
  • Nausea
  • Diarrhoea
  • Vomiting

What if I have taken an overdose of ZEKACIN 250MG INJECTION 2ML

The overdose of ZEKACIN 250MG INJECTION 2ML is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with ZEKACIN 250MG INJECTION 2ML, please inform your doctor immediately.

Drug Warnings

Do not take ZEKACIN 250MG INJECTION 2ML if you are allergic to any of the components, antibiotics related to aminoglycosides, sulphites, if you are suffering from a disorder called myasthenia gravis (severe weakness of muscles in the body), and dehydration. Talk to your doctor before taking ZEKACIN 250MG INJECTION 2ML if you have any kidney problems, or hearing problems such as tinnitus (buzzing or ringing in the ears). You are advised not to drive or operate heavy machinery after taking ZEKACIN 250MG INJECTION 2ML as it may cause dizziness. If you are pregnant or breastfeeding, talk to your doctor before taking ZEKACIN 250MG INJECTION 2ML. The doctor will prescribe you ZEKACIN 250MG INJECTION 2ML only if the benefits outweigh the potential risks.

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical
AmikacinCidofovir
Critical

Drug-Drug Interactions

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AmikacinBCG vaccine
Critical
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Coadministration of BCG vaccine with ZEKACIN 250MG INJECTION 2ML can reduce its effectiveness.

How to manage the interaction:
Taking ZEKACIN 250MG INJECTION 2ML with the BCG vaccine can result in an interaction. Furthermore, if you have active TB, you should not undergo BCG therapy. However, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
AmikacinCidofovir
Critical
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Co-administration of cidofovir with ZEKACIN 250MG INJECTION 2ML can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Cidofovir with ZEKACIN 250MG INJECTION 2ML is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, dizziness, or palpitations, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
AmikacinBumetanide
Severe
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Coadministration of ZEKACIN 250MG INJECTION 2ML with Bumetanide can cause side effects like kidney problems. Patients who are dehydrated or with a history of kidney problems are at a higher risk.

How to manage the interaction:
Although taking ZEKACIN 250MG INJECTION 2ML and bumetanide together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience ringing in the ears, irregular urination, vomting, or muscle cramps, consult the doctor. Do not discontinue any medications without a doctor's advice.
AmikacinDeferasirox
Severe
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Coadministration of ZEKACIN 250MG INJECTION 2ML with Deferasirox can increase the risk of developing kidney problems.

How to manage the interaction:
Although taking ZEKACIN 250MG INJECTION 2ML and Deferasirox together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience vomiting, irregular urination, swelling, shortness of breath, muscle cramps, dizziness, or palpitations, seek immediate medical attention. Make sure to hydrate while taking these medications. Do not discontinue any medications without a doctor's advice.
AmikacinPolymyxin b
Severe
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Coadministration of ZEKACIN 250MG INJECTION 2ML with Polymyxin B may increase the risk of severe side effects.

How to manage the interaction:
Although taking ZEKACIN 250MG INJECTION 2ML and Polymyxin- b together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience ringing in the ears, difficulty breathing, vomiting, irregular urination, swelling, muscle pain, dizziness, or palpitation. Do not stop using any medications without talking to a doctor.
AmikacinRocuronium bromide
Severe
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Co-administration of ZEKACIN 250MG INJECTION 2ML with rocuronium bromide enhances the effects of rocuronium bromide leading to the risk of breathing problems.

How to manage the interaction:
Taking Rocuronium bromide with ZEKACIN 250MG INJECTION 2ML together can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor if you experience shortness of breath, chest pain, or palpitation. Do not stop using any medications without a doctor's advice.
AmikacinEtacrynic acid
Severe
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Coadministration of ZEKACIN 250MG INJECTION 2ML with Ethacrynic acid can increase the risk of developing side effects. Elderly patients, those who are dehydrated, and patients with a history of kidney problems are at greater risk.

How to manage the interaction:
Although taking Etacrynic acid and ZEKACIN 250MG INJECTION 2ML together can cause an interaction, it can be taken if your doctor has suggested it. Consult a doctor if you experience decreased urination, vomting, shortness of breath, blurred vision, or muscle cramps. Do not stop using any medications without a doctor's advice.
AmikacinHuman immunoglobulin
Severe
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Taking Human immunoglobulin with ZEKACIN 250MG INJECTION 2ML, may raise the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with ZEKACIN 250MG INJECTION 2ML can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, or palpitation, consult a doctor. Do not stop using any medications without talking to a doctor.
AmikacinColistin
Severe
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Coadministration of Colistin with ZEKACIN 250MG INJECTION 2ML can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and ZEKACIN 250MG INJECTION 2ML, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
AmikacinSuxamethonium
Severe
How does the drug interact with ZEKACIN 250MG INJECTION 2ML:
Co-administration of ZEKACIN 250MG INJECTION 2ML with Suxamethonium enhances the effects of atracurium leading to the risk of breathing problems.

How to manage the interaction:
Although there is a possible interaction between Suxamethonium and ZEKACIN 250MG INJECTION 2ML, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience shortness of breath, chest discomfort, palpitation, or dizziness, Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food such as whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

ZEKACIN 250MG INJECTION 2ML Substitute

Substitutes safety advice
  • Mikacin 250 Injection 2 ml

    27.45per tablet
  • Alfakim 250 mg Injection 2 ml

    20.93per tablet
  • ALFAKIM 250MG INJECTION 2ML

    by AYUR

    22.95per tablet
  • AMISWISS 250MG INJECTION

    29.57per tablet
  • Amiject 250mg Injection 2 ml

    16.65per tablet
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Alcohol

Caution

You are advised not to consume alcohol while taking ZEKACIN 250MG INJECTION 2ML as it may lead to unwanted side-effects.

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Pregnancy

Caution

ZEKACIN 250MG INJECTION 2ML belongs to pregnancy category-D. If you are pregnant, the doctor will prescribe ZEKACIN 250MG INJECTION 2ML only if the benefits outweigh the potential risks.

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Breast Feeding

Caution

If you are breastfeeding, talk to your doctor before taking ZEKACIN 250MG INJECTION 2ML. The doctor will prescribe ZEKACIN 250MG INJECTION 2ML only if the benefits outweigh the potential risks.

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Driving

Caution

ZEKACIN 250MG INJECTION 2ML may cause dizziness, therefore you are advised to drive and operate machinery only if you are alert.

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Liver

Safe if prescribed

ZEKACIN 250MG INJECTION 2ML is safe to be used in people with liver problems if prescribed by a doctor.

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Kidney

Caution

ZEKACIN 250MG INJECTION 2ML should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.

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Children

Safe if prescribed

ZEKACIN 250MG INJECTION 2ML can be given to children if prescribed by the doctor. Dose adjustment may be required as per the age and weight of the child.

FAQs

ZEKACIN 250MG INJECTION 2ML is used to treat bacterial infections.
ZEKACIN 250MG INJECTION 2ML belongs to the group of antibiotic medicines called as aminoglycosides. ZEKACIN 250MG INJECTION 2ML is used to treat serious bacterial infections. ZEKACIN 250MG INJECTION 2ML works by inhibiting the production of bacterial proteins which are necessary for the existence of the bacteria. Thereby, leads to the death of bacteria.
Yes, ZEKACIN 250MG INJECTION 2ML may lead to changes in kidney function. Your doctor will advise you to get blood and urine tests to evaluate the levels of protein or white/red blood cells and creatinine or nitrogen in blood samples. ZEKACIN 250MG INJECTION 2ML should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.
Yes, ZEKACIN 250MG INJECTION 2ML may cause dizziness. You are advised not to drive or operate heavy machinery after taking ZEKACIN 250MG INJECTION 2ML as it may cause dizziness and can affect vision. Drive or operate machinery only if you are alert.
Yes, antibiotics may cause diarrhoea. Include foods containing probiotics such as yoghurt, cheese, and buttermilk in your diet as it would help in proper digestion. Also, eat fibre-rich food like whole grain, beans, peas, and bananas. Consult your doctor if you have severe diarrhoea. Do not take any anti-diarrheal medicine without consulting your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India
Other Info - ZEK0001

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