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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zedex-P Cold Syrup is used to treat the allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Also, it inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zedex-P Cold Syrup

Zedex-P Cold Syrup is a cough and cold medication used to treat allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus'. This virus attacks the body through the mouth, nose, or eyes and spreads easily through droplets in the air when a person who is sick sneezes, coughs, or talks.

Zedex-P Cold Syrup is composed of three medicines, namely Levocetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Take Zedex-P Cold Syrup with or without food as prescribed by your doctor. Do not crush, chew, or break it. If Zedex-P Cold Syrup is in syrup form, measure it with a measuring cup. Your doctor will recommend how often you take Zedex-P Cold Syrup based on your medical condition. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Most of these side effects of Zedex-P Cold Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zedex-P Cold Syrup or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Zedex-P Cold Syrup. It should be used with caution in children only if prescribed by a doctor. If you have high blood pressure, kidney or liver problems, coronary artery disease (heart problems), or are receiving any monoamine oxidase inhibitor (MAO) therapy to treat depression like Isocarboxazid, Phenelzine, Selegiline, Tranylcypromine etc., inform your doctor before taking Zedex-P Cold Syrup. Do not drink alcohol with Zedex-P Cold Syrup as it may potentiate the dizziness property of Cetrizine. Hence, it is advisable not to drive or operate heavy machinery or do hazardous work, which requires mental alertness. Taking more than 4 gm per day of paracetamol can damage your liver severely, so if you have liver problems, please contact your doctor.

Uses of Zedex-P Cold Syrup

Zedex-P Cold Syrup is used in the treatment of allergies and the common cold. The detailed uses of Zedex-P Cold Syrup are as follows:

  • Relieves Cold and Allergy Symptoms: Zedex-P Cold Syrup helps to reduce cough, sneezing, itchy nose/throat, runny nose, nasal congestion, and watery eyes caused by colds or allergies.
  • Reduces Nasal Congestion: Zedex-P Cold Syrup contains a decongestant that narrows blood vessels in the nasal passages to relieve a stuffy nose and improve airflow.
  • Reduces Fever and Body Aches: Zedex-P Cold Syrup helps to lower fever and relieve headache, sore throat, and body pain associated with colds and flu.

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Directions for Use

  • Zedex-P Cold Syrup can be taken with or without food, as advised by your doctor.
  • It is usually taken twice daily or as prescribed by your doctor.
  • Swallow Zedex-P Cold Syrup as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Zedex-P Cold Syrup is primarily used to treat common cold symptoms and reduce symptoms of allergies. It is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy noses. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

How Zedex-P Cold Syrup Works

Zedex-P Cold Syrup is composed of three medicines, namely Levocetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zedex-P Cold Syrup

Do not take more than the prescribed dose of Zedex-P Cold Syrup as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Zedex-P Cold Syrup if you are allergic to Zedex-P Cold Syrup or any of its ingredients, are pregnant or breastfeeding before starting Zedex-P Cold Syrup. If you have high blood pressure,  kidney or liver disease, coronary artery disease, please do not take Zedex-P Cold Syrup as it is known to interact. Also, inform your doctor about all other medications you have been taking before starting Zedex-P Cold Syrup. Do not stop taking Zedex-P Cold Syrup even if you feel better without asking your doctor as your symptoms may come back and may even worsen your condition. Zedex-P Cold Syrup may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Zedex-P Cold Syrup if you have taken any MAO inhibitor (anti-depressant medication) in the past 14 days.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zedex-P Cold Syrup:
Taking Zedex-P Cold Syrup with Propofol may lead to increased levels of Zedex-P Cold Syrup leading to side effects like high blood pressure.

How to manage the interaction:
Taking Zedex-P Cold Syrup with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Zedex-P Cold Syrup:
Co-administration of Selegiline with Zedex-P Cold Syrup together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Zedex-P Cold Syrup is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zedex-P Cold Syrup:
Co-administration of Zedex-P Cold Syrup with Sevoflurane can increase the levels of Zedex-P Cold Syrup and lead to side effects.

How to manage the interaction:
Taking Zedex-P Cold Syrup with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Zedex-P Cold Syrup:
Taking Furazolidone with Zedex-P Cold Syrup can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Zedex-P Cold Syrup is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Zedex-P Cold Syrup only after 14 days of stopping Furazolidone.
How does the drug interact with Zedex-P Cold Syrup:
Taking Tranylcypromine with Zedex-P Cold Syrup can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Zedex-P Cold Syrup is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
LevocetirizineEsketamine
Severe
How does the drug interact with Zedex-P Cold Syrup:
Using esketamine together with Zedex-P Cold Syrup may increase side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Taking Zedex-P Cold Syrup with Esketamine together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
PhenylephrineIsoflurane
Severe
How does the drug interact with Zedex-P Cold Syrup:
Taking Zedex-P Cold Syrup with Isoflurane may lead to increased side effects of Zedex-P Cold Syrup.

How to manage the interaction:
Co-administration of Zedex-P Cold Syrup with Isoflurane can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
PhenylephrinePhenelzine
Severe
How does the drug interact with Zedex-P Cold Syrup:
Co-administration of Zedex-P Cold Syrup with Phenelzine can result in extremely high blood pressure which may be serious.

How to manage the interaction:
There may be a possibility of interaction between Zedex-P Cold Syrup and Phenelzine, but it can be taken if prescribed by a doctor. However, If you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zedex-P Cold Syrup:
Taking Zedex-P Cold Syrup with Methylergometrine can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Zedex-P Cold Syrup with Methylergometrine can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Zedex-P Cold Syrup:
Co-administration of Amoxapine and Zedex-P Cold Syrup together may lead to side effects like increased blood pressure.

How to manage the interaction:
Taking Zedex-P Cold Syrup and Amoxapine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. It is advised to maintain blood pressure. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.

  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health. 
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Zedex-P Cold Syrup as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

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Alcohol

Unsafe

Avoid consumption of alcohol with Zedex-P Cold Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Zedex-P Cold Syrup.

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Pregnancy

Caution

The safety of Zedex-P Cold Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Zedex-P Cold Syrup in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Zedex-P Cold Syrup may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Zedex-P Cold Syrup.

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Liver

Caution

Take Zedex-P Cold Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zedex-P Cold Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Zedex-P Cold Syrup is not recommended for children below 12 years of age. However, please consult a doctor before giving Zedex-P Cold Syrup to children.

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Heart

Unsafe

Zedex-P Cold Syrup is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Unsafe

Zedex-P Cold Syrup is not recommended for use in elderly patients as it can lead to side effects.

FAQs

Zedex-P Cold Syrup is a cough and cold medication primarily used to treat allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat.

Zedex-P Cold Syrup is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nostrils and the passage and reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

No, you are not recommended to stop taking Zedex-P Cold Syrup without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Zedex-P Cold Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Zedex-P Cold Syrup, please consult your doctor.

No, you should not take Zedex-P Cold Syrup along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Zedex-P Cold Syrup.

Yes, Cetirizine present in Zedex-P Cold Syrup may cause drowsiness. It is not necessary for everyone taking Zedex-P Cold Syrup to experience this side effect. Therefore, avoid driving and drinking alcohol if you feel drowsy after taking Zedex-P Cold Syrup.

Country of origin

India
Other Info - ZE74902

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