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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zedep Capsule is used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. It contains Fluoxetine, which increases serotonin concentrations and helps in regulating mood and treats depression. In some cases, you may experience common side effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

FLUOXETINE-20MG

Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Zedep Capsule

Zedep Capsule belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. Depression is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.
 
Zedep Capsule contains ‘Fluoxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.
 
Take Zedep Capsule as prescribed. You are advised to take Zedep Capsule for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Zedep Capsule on your own as it could lead to withdrawal symptoms. Do not take Zedep Capsule if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Zedep Capsule may cause dizziness and might impair your reactions. Zedep Capsule should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Zedep Capsule as it could lead to increased dizziness.  Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Zedep Capsule

Treatment of Depression, Obsessive-Compulsive Disorder (OCD), Bulimia nervosa (eating disorder).

Directions for Use

Take Zedep Capsule with or without food. Your doctor will decide for how long you need to take Zedep Capsule based on your medical condition and response to treatment. Take Zedep Capsule exactly as prescribed by the doctor. Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

Zedep Capsule belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Zedep Capsule is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder with or without agoraphobia. Zedep Capsule works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression. Zedep Capsule may also be used to treat premenstrual dysphoric disorder (a severe form of premenstrual syndrome). Zedep Capsule has fewer unwanted effects than other antidepressant drugs. Zedep Capsule is used in combination with other drugs to treat bipolar disorder and treatment-resistant depression.

How Zedep Capsule Works

Zedep Capsule contains ‘Fluoxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zedep Capsule

  • Insomnia (difficulty sleeping)
  • Headache
  • Diarrhoea
  • Nausea
  • Fatigue
  • Dry mouth
  • Loss of appetite
  • Indigestion

What if I have taken an overdose of Zedep Capsule

Do not take more than the prescribed dose of Zedep Capsule as it may cause overdose. The symptoms of overdose include drowsiness, tremor, fast heart rate, vomiting and nausea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Zedep Capsule if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MOA) or have taken them in the last 14days, or if you are taking metoprolol (used to treat high blood pressure). Do not take Zedep Capsule along with opioid antagonists such as buprenorphine and naloxone as it might lead to a serious condition called serotonin syndrome. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, glaucoma, diabetes, bleeding disorders, or hyponatremia (low sodium levels).  Do not take Zedep Capsule if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Zedep Capsule may cause dizziness and might impair your reactions. Zedep Capsule should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Zedep Capsule as it could lead to increased dizziness. 

Drug-Drug Interactions

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FluoxetineTramadol
Severe
FluoxetineGatifloxacin
Severe

Drug-Drug Interactions

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FluoxetineTramadol
Severe
How does the drug interact with Zedep Capsule 10's:
Taking Zedep Capsule 10's with tramadol may increase the risk of a serotonin syndrome. It may also increase the risk of seizures not related to the serotonin syndrome.

How to manage the interaction:
Although there is a possible interaction, Zedep Capsule 10's can be taken with tramadol if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medications without consulting a doctor.
FluoxetineGatifloxacin
Severe
How does the drug interact with Zedep Capsule 10's:
Taking Zedep Capsule 10's with gatifloxacin may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Zedep Capsule 10's can be taken with gatifloxacin if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.
FluoxetineParoxetine
Severe
How does the drug interact with Zedep Capsule 10's:
Taking Zedep Capsule 10's together with paroxetine may increase the risk of Serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Although there is a possible interaction, Zedep Capsule 10's can be taken with paroxetine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea (or) side effects such as cognitive and motor impairment, insomnia, drowsiness, seizures, abnormal bleeding, sexual dysfunction.
FluoxetineCitalopram
Severe
How does the drug interact with Zedep Capsule 10's:
Taking Zedep Capsule 10's with citalopram may increase the risk of a rare but serious condition called the serotonin syndrome. Combining these medications can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Although there is a possible interaction, Zedep Capsule 10's can be taken with citalopram if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Let the doctor know if you notice symptoms of serotonin syndrome such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
FluoxetineArsenic trioxide
Severe
How does the drug interact with Zedep Capsule 10's:
Combining Zedep Capsule 10's with Arsenic trioxide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Arsenic trioxide with Zedep Capsule 10's can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any fainting or irregular heartbeat, it's best to go to the hospital for check-ups. If you experience symptoms like fainting, irregular heartbeat, dizziness, or shortness of breath, make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
FluoxetinePentazocine
Severe
How does the drug interact with Zedep Capsule 10's:
Co-administration of Pentazocine with Zedep Capsule 10's can increase the risk of serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Zedep Capsule 10's, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
FluoxetineRizatriptan
Severe
How does the drug interact with Zedep Capsule 10's:
Taking Zedep Capsule 10's with rizatriptan may increase the risk of a serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Zedep Capsule 10's and Rizatriptan, it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking of hands and legs, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.
FluoxetineOndansetron
Severe
How does the drug interact with Zedep Capsule 10's:
Co-administration of Ondansetron with Zedep Capsule 10's can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking ondansetron along with Zedep Capsule 10's can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
FluoxetineDofetilide
Severe
How does the drug interact with Zedep Capsule 10's:
Combining Zedep Capsule 10's with Dofetilide can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Zedep Capsule 10's with Dofetilide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away: an irregular heart rhythm, a heart condition, congenital long qt syndrome, conduction abnormalities, severe or prolonged diarrhea, vomiting, complications, sudden dizziness, lightheadedness, fainting, shortness of breath, or palpitations. Do not stop using any medications without talking to a doctor.
FluoxetineDesvenlafaxine
Severe
How does the drug interact with Zedep Capsule 10's:
Taking Zedep Capsule 10's with desvenlafaxine might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction, Zedep Capsule 10's can be taken with desvenlafaxine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.

  • Regularly attend therapy sessions.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.

  • Avoid smoking and alcohol consumption.

  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Zedep Capsule Substitute

Substitutes safety advice
  • Fludac Capsule 15's

    3.93per tablet
  • Prodep Capsule 10's

    4.01per tablet
  • Flunil-20 Capsule 10's

    4.01per tablet
  • Flunil Suspension 60 ml

    1.79per tablet
  • Floatin-20 Tablet 10's

    4.01per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zedep Capsule as it may cause increased dizziness.

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Pregnancy

Caution

Zedep Capsule belongs to pregnancy category C. Please consult your doctor before taking Zedep Capsule if you are pregnant, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Zedep Capsule may pass into breastmilk. Consult your doctor before taking Zedep Capsule ; your doctor will decide whether Zedep Capsule can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Zedep Capsule may cause dizziness and might impair your reactions. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Zedep Capsule should not be given to children below 8years as the safety and effectiveness have not been established.

FAQs

Zedep Capsule is used to treat Depression, Obsessive-Compulsive Disorder (OCD), and Bulimia nervosa (eating disorder).
Zedep Capsule works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.
Do not discontinue Zedep Capsule without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually continue taking Zedep Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Zedep Capsule ; the doctor may reduce the dose gradually.
Zedep Capsule may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.
Dry mouth could be a side-effect of Zedep Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Please consult your doctor before taking Zedep Capsule if you have glaucoma as it might cause increased pressure in the eye.
Consult tour doctor before taking Zedep Capsule if you are diabetic as it might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Zedep Capsule . Talk to your doctor if you experience fluctuations in blood sugar levels.
Zedep Capsule might increase the risk of bone fractures. Talk to your doctor before taking Zedep Capsule if you have osteoporosis. Consult your doctor if you experience bone pain.
Zedep Capsule may cause weight loss due to loss of appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight. Please consult your doctor if you experience fluctuations in weight while taking Zedep Capsule .

Country of origin

India

Manufacturer/Marketer address

Plot No. 45, N.T.M., Sector -26, Chandigarh
Other Info - ZED0030

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