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  3. Zaxyben 50mg Injection

Zaxyben 50mg Injection, Pack of 1 Injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zaxyben 50mg Injection is an antihypertensive medicine used in the treatment of hypertension (high blood pressure) caused by phaeochromocytoma (tumour of the adrenal glands). This medicine works by opposing certain hormones produced by the tumour of the adrenal gland and thus relaxes and widens blood vessels and lowers increased blood pressure. It is advised to avoid alcohol consumption as it can worsen the condition.
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Composition :

PHENOXYBENZAMINE-50MG

Manufacturer/Marketer :

Molekule (India) Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Zaxyben 50mg Injection

Zaxyben 50mg Injection belongs to a group of medicines called antihypertensives used to treat hypertension (high blood pressure) caused by phaeochromocytoma (tumour of the adrenal glands). Hypertension is a condition in which the force of blood against the artery walls is very high. It will be an addition to the workload of the heart and arteries.

Zaxyben 50mg Injection contains Phenoxybenzamine, an alpha-blocker that opposes certain hormones produced by the tumour of the adrenal gland that constricts and narrows blood vessels. Thereby, it relaxes and widens blood vessels and lowers increased blood pressure.

Zaxyben 50mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience dizziness, lightheadedness, blocked nose, diarrhoea, tiredness, narrowing of the pupil of the eye or ejaculation failure during intercourse. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Zaxyben 50mg Injection or any other medicines, please tell your doctor. Zaxyben 50mg Injection is not recommended for children unless advised by a doctor. If you are pregnant or breastfeeding, please consult a doctor. Avoid taking Zaxyben 50mg Injection if you ever had a heart attack or stroke. You are recommended to avoid alcohol consumption with Zaxyben 50mg Injection as it may increase the risk of dangerously low blood pressure. Drive only if you are alert as Zaxyben 50mg Injection may cause dizziness or light-headedness. 

Uses of Zaxyben 50mg Injection

Treatment of Hypertension (high blood pressure)

Directions for Use

Zaxyben 50mg Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Zaxyben 50mg Injection contains Phenoxybenzamine used to treat high blood pressure caused by phaeochromocytoma (tumour of the adrenal glands). Zaxyben 50mg Injection opposes the action of certain hormones produced by the tumour of the adrenal gland that constricts and narrows blood vessels. Thereby, it relaxes and widens blood vessels and lowers high blood pressure.

How Zaxyben 50mg Injection Works

Zaxyben 50mg Injection contains Phenoxybenzamine, an alpha-blocker that opposes certain hormones produced by the tumour of the adrenal gland that constricts and narrows blood vessels. Thereby, it relaxes and widens blood vessels and lowers increased blood pressure.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Zaxyben 50mg Injection

Zaxyben 50mg Injection is a parenteral formulation,hence the chance of overdose may be less. However, keep a track of your medicine as overdose of Zaxyben 50mg Injection may cause serious side effects. Symptoms may include dizziness or fainting, lethargy, vomiting, and shock. Seek immediate medical attention if you observe any of these side effects.

Drug Warnings

If you are allergic to Zaxyben 50mg Injection or any other medicines, please tell your doctor. Zaxyben 50mg Injection is not recommended for children unless advised by a doctor. If you are pregnant or breastfeeding, please consult a doctor. Avoid taking Zaxyben 50mg Injection if you ever had a heart attack or stroke. You are recommended to avoid alcohol consumption with Zaxyben 50mg Injection as it may increase the risk of dangerously low blood pressure. Drive only if you are alert as Zaxyben 50mg Injection may cause dizziness or light-headedness. If you take any medicines to treat heart problems or blood pressure, please inform your doctor before taking Zaxyben 50mg Injection.

Diet & Lifestyle Advise

  • Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, reacting in certain situations, and doing activities that you enjoy by making time for yourself.
  • Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ALPHA BLOCKERS

Zaxyben 50mg Injection Substitute

Substitutes safety advice

  • Biophenox 50Mg Inj

    by AYUR

    ₹1395.00per tablet

  • Fenoxene Injection 1ml

    by AYUR

    ₹2523.40per tablet

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while on treatment with Zaxyben 50mg Injection as it may increase the risk of dangerously low blood pressure.

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Pregnancy

Consult your doctor

Zaxyben 50mg Injection is not recommended for pregnant women unless clearly necessary. Therefore, if you are pregnant or planning pregnancy, please inform your doctor before receiving Zaxyben 50mg Injection.

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Breast Feeding

Consult your doctor

Zaxyben 50mg Injection is usually not recommended for breastfeeding mothers. Therefore, please inform your doctor if you are a breastfeeding mother before receiving Zaxyben 50mg Injection.

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Driving

Caution

Zaxyben 50mg Injection may cause dizziness or light-headedness in some people. Therefore, avoid driving if you feel dizzy or lightheaded after taking Zaxyben 50mg Injection.

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Liver

Caution

Inform your doctor if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Inform your doctor if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Zaxyben 50mg Injection is not recommended for children unless advised by the doctor.

FAQs

Zaxyben 50mg Injection is an antihypertensive medicine used in the treatment of hypertension (high blood pressure) caused by phaeochromocytoma (tumour of the adrenal glands).

Zaxyben 50mg Injection contains Phenoxybenzamine that works by opposing the action of certain hormones produced by the adrenal gland tumor that constricts and narrows blood vessels. Thereby, it relaxes and widens blood vessels and lowers high blood pressure.

You are not recommended to take Zaxyben 50mg Injection with atenolol as it may increase orthostatic hypotensive effects of Zaxyben 50mg Injection such as dizziness, fainting, or lightheadedness. However, please consult a doctor before taking other medicines with Zaxyben 50mg Injection.

Zaxyben 50mg Injection should be used with caution in patients suffering from kidney problems as it may increase the risk of adverse effects. Therefore, if you have any kidney disease, inform your doctor before taking Zaxyben 50mg Injection.

Zaxyben 50mg Injection may cause dizziness in some patients. Therefore, it is advised to get up slowly from a sitting or lying position to avoid such side effects. Also, if you feel dizzy after taking Zaxyben 50mg Injection, avoid driving or operating heavy machinery.

Zaxyben 50mg Injection should be taken for as long as it has been prescribed by the doctor. The dose and duration will be determined by the doctor based on your medical condition.

People who are allergic to any of the components in this medicine should not take Zaxyben 50mg Injection. It is also not recommended in conditions where a fall in blood pressure may be undesirable.

Zaxyben 50mg Injection reduces blood pressure and increases the release of the chemical messenger (noradrenaline) which results in reflex tachycardia (fast heart rate). Let the doctor know if you experience a fast heart rate.

Zaxyben 50mg Injection is used for the treatment of hypertension associated with the rare adrenal gland tumour, pheochromocytoma.

Zaxyben 50mg Injection helps to lower the elevated blood pressure caused by pheochromocytoma. It is an adrenal gland tumour that causes adrenal glands to release large amounts of chemicals called catecholamines into the blood, which raises blood pressure. Zaxyben 50mg Injection lowers blood pressure by blocking alpha receptors.

Yes, Zaxyben 50mg Injection may affect sex life. It may cause sexual dysfunction like ejaculation failure during intercourse. Consult the doctor if you have any concerns.

The symptoms of an overdose of Zaxyben 50mg Injection include vomiting, fast heart rate, fainting, or dizziness. Consult the doctor if you experience any of these symptoms.

Zaxyben 50mg Injection starts working in an hour. However, it might take a few hours to notice the effects of the medicine.

The side effects of Zaxyben 50mg Injection include vomiting, nausea, dizziness, blocked nose, light-headedness, tachycardia, tiredness, ejaculation failure during intercourse, and narrowing of the pupil of the eye. Consult the doctor if any side effects persist or worsen.

Country of origin

India
Other Info - ZAXY240

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Author Details

Doctor imageDoctor badge

Written By

Veda Maddala

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:45 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://archive.hshsl.umaryland.edu/bitstream/handle/10713/15464/Phenoxybenzamine_Final_2020_12.pdf?sequence=1&isAllowed=y
  2. https://go.drugbank.com/drugs/DB00925
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