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Composition

COLISTIMETHATE

Manufacturer/Marketer

Cipla Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About XYLISTIN 4.5MIU INJECTION

XYLISTIN 4.5MIU INJECTION belongs to a class of drugs called antibiotics used in the treatment of severe bacterial infections. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. XYLISTIN 4.5MIU INJECTION does not work against infections caused by a virus.

XYLISTIN 4.5MIU INJECTION contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Take XYLISTIN 4.5MIU INJECTION as prescribed by your doctor. You are advised to take XYLISTIN 4.5MIU INJECTION for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, stomach upset, tingling, or difficulty in breathing. Most of these side effects of XYLISTIN 4.5MIU INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to XYLISTIN 4.5MIU INJECTION or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking XYLISTIN 4.5MIU INJECTION. If you are pregnant or breastfeeding, please inform your doctor before taking XYLISTIN 4.5MIU INJECTION. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as XYLISTIN 4.5MIU INJECTION may cause confusion, vision problems, or dizziness.  If you are on dialysis, inform your doctor before taking XYLISTIN 4.5MIU INJECTION so that the dose may be reduced accordingly.

Uses of XYLISTIN 4.5MIU INJECTION

Treatment of Several bacterial infections

Medicinal Benefits

XYLISTIN 4.5MIU INJECTION contains Colistimethate, a narrow-spectrum antibiotic that is active against gram-negative bacteria. XYLISTIN 4.5MIU INJECTION binds to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria. XYLISTIN 4.5MIU INJECTION is used when other antibiotics are not suitable.

Side Effects of XYLISTIN 4.5MIU INJECTION

  • Dizziness
  • Stomach upset
  • Tingling
  • Difficulty in breathing

Directions for Use

XYLISTIN 4.5MIU INJECTION will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to XYLISTIN 4.5MIU INJECTION or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking XYLISTIN 4.5MIU INJECTION. If you are pregnant or breastfeeding, please inform your doctor before taking XYLISTIN 4.5MIU INJECTION. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as XYLISTIN 4.5MIU INJECTION may cause confusion, vision problems, or dizziness. If you are on dialysis, inform your doctor before taking XYLISTIN 4.5MIU INJECTION so that the dose may be reduced accordingly. Inform your anesthetist that you are taking XYLISTIN 4.5MIU INJECTION as it may increase the effects of muscle relaxants used in general anesthesia. You are recommended to complete the full course of XYLISTIN 4.5MIU INJECTION as prescribed by your doctor for effective results.

Therapeutic Class

ANTIBIOTICS

Drug Interactions

Drug-Drug Interaction: XYLISTIN 4.5MIU INJECTION may interact with antibiotics (amikacin, netilmicin, tobramycin, gentamicin, erythromycin, clarithromycin, azithromycin, ciprofloxacin, norfloxacin, ofloxacin).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have myasthenia gravis (muscle weakness), kidney problems or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking XYLISTIN 4.5MIU INJECTION.

Drug-Drug Interactions Checker List

  • AMIKACIN
  • NETILIMICIN
  • TOBRAMYCIN
  • GENTAMICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • AZITHROMYCIN
  • CIPROFLOXACIN
  • NORFLOXACIN
  • OFLOXACIN

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of XYLISTIN 4.5MIU INJECTION to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking XYLISTIN 4.5MIU INJECTION.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

What if I have taken an overdose of XYLISTIN 4.5MIU INJECTION

Use XYLISTIN 4.5MIU INJECTION only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, confusion, loss of balance/coordination, rapid eye movement, severe numbness/tingling, weak/shallow breathing, problems with speech, and loss of consciousness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Special Advise

  • Regular blood tests are recommended to monitor the levels of XYLISTIN 4.5MIU INJECTION in blood and kidney functioning.
  • Inform your anaesthetist that you are taking XYLISTIN 4.5MIU INJECTION as it may increase the effects of muscle relaxants used in general anaesthesia.

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grows in the body and cause infection. It can target any part of the body and multiple very quickly. Bacteria come in three basic shapes, namely spherical, rod or spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have cell wall). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever and tiredness.

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Alcohol

Caution

Interaction of XYLISTIN 4.5MIU INJECTION with alcohol is unknown. Please consult a doctor before consuming alcohol while using XYLISTIN 4.5MIU INJECTION.

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Pregnancy

Caution

XYLISTIN 4.5MIU INJECTION is a category C pregnancy drug and is given to pregnant women only if it is essential. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

XYLISTIN 4.5MIU INJECTION may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

XYLISTIN 4.5MIU INJECTION may cause confusion, vision problems or dizziness. Therefore, avoid driving if you experience any of these symptoms after taking XYLISTIN 4.5MIU INJECTION.

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Liver

Caution

Take XYLISTIN 4.5MIU INJECTION with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take XYLISTIN 4.5MIU INJECTION with caution, especially if you have a history of Kidney diseases/conditions as XYLISTIN 4.5MIU INJECTION may affect kidney function. The dose may be adjusted by your doctor as required.

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Children

Caution

XYLISTIN 4.5MIU INJECTION should be used with caution in children and in doses as prescribed by a doctor. Special care should be taken in new-born and premature babies as kidneys are not developed fully.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - XYL0094

Author Details

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FAQs

XYLISTIN 4.5MIU INJECTION is used to treat bacterial infections.
XYLISTIN 4.5MIU INJECTION contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria.
You are not recommended to take XYLISTIN 4.5MIU INJECTION with gentamicin as co-administration of these two medicines may increase the risk of severe adverse effects such as kidney problems, hearing loss or respiratory depression especially in elderly people and in those who have preexisting kidney disease or who are dehydrated. However, please consult your doctor before taking XYLISTIN 4.5MIU INJECTION with other medicines.
XYLISTIN 4.5MIU INJECTION may cause dizziness as a common side effect. Avoid driving if you feel dizzy after taking XYLISTIN 4.5MIU INJECTION. However, if the condition persists or worsens, please consult a doctor.
XYLISTIN 4.5MIU INJECTION should be used with caution in patients receiving dialysis (the process of filtration and purification of blood using a machine). Therefore, if you are receiving dialysis, please inform your doctor before taking XYLISTIN 4.5MIU INJECTION so that the dose may be adjusted accordingly.
You are recommended to take XYLISTIN 4.5MIU INJECTION with extreme caution if you have kidney disease as it may worsen the condition. Regular monitoring of kidney functioning is recommended while taking XYLISTIN 4.5MIU INJECTION. Therefore, inform your doctor if you have any kidney problems before taking XYLISTIN 4.5MIU INJECTION.

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