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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Xone XP 1.125 gm Injection 5 ml is used to treat bacterial infections. It contains Ceftriaxone and Tazobactum which work by damaging the bacterial cell wall and killing bacteria. In some cases, this medicine may cause side effects such as diarrhoea, rash, abnormal white blood cells and platelets. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Xone XP 1.125 gm Injection 5 ml

Xone XP 1.125 gm Injection 5 ml belongs to a class of medication called 'antibiotics' used to treat several bacterial infections of the urinary tract, blood, bones and joints, heart, brain, chest, ears, skin, or soft tissues. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Xone XP 1.125 gm Injection 5 ml does not work against infections caused by the virus.

Xone XP 1.125 gm Injection 5 ml is a combination of two drugs: Ceftriaxone (antibiotic) and Tazobactum (beta-lactamase inhibitor). Ceftriaxone belongs to the class of antibiotics that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.

You are advised to take Xone XP 1.125 gm Injection 5 ml for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhea, rash, or abnormalities with white blood cells and platelets. Most of these side effects of Xone XP 1.125 gm Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Xone XP 1.125 gm Injection 5 ml, penicillins, or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Xone XP 1.125 gm Injection 5 ml. Drive only if you are alert as Xone XP 1.125 gm Injection 5 ml may cause dizziness. You are recommended to complete the full course of Xone XP 1.125 gm Injection 5 ml as prescribed by your doctor for effective results. Xone XP 1.125 gm Injection 5 ml may interact with certain tests such as glucose (sugar) in urine and coomb’s test, giving unusual results. Therefore, inform the doctor that you are taking Xone XP 1.125 gm Injection 5 ml before undergoing any tests.

Uses of Xone XP 1.125 gm Injection 5 ml

Treatment of Bacterial infections

Directions for Use

Xone XP 1.125 gm Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Xone XP 1.125 gm Injection 5 ml is a combination of two drugs: Ceftriaxone (antibiotic) and Tazobactum (beta-lactamase inhibitor) used to treat several bacterial infections. Ceftriaxone is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance. 

How Xone XP 1.125 gm Injection 5 ml Works

Xone XP 1.125 gm Injection 5 ml is a combination of two drugs: Ceftriaxone (antibiotic) and Tazobactum (beta-lactamase inhibitor). Ceftriaxone belongs to the class of antibiotics that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Xone XP 1.125 gm Injection 5 ml

  • Diarrhoea
  • Rash
  • Raised white blood cells
  • Raised platelets
  • Nausea
  • Vomiting
  • Upset stomach
  • Blood clots
  • Dizziness
  • headache
  • a lump where the medicine was injected,
  • Sweating

What if I have taken an overdose of Xone XP 1.125 gm Injection 5 ml

Since Xone XP 1.125 gm Injection 5 ml is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience symptoms of overdose such as nausea, vomiting, and diarrhoea.

Drug Warnings

If you are allergic to Xone XP 1.125 gm Injection 5 ml, penicillins, or any other medicines, please tell your doctor. If you have kidney or liver problems, diarrhea, hemolytic anemia (reduction in red blood cells that may make your skin pale yellow and cause breathlessness or weakness), kidney or gall stones, or inflammation of the large intestine, inform your doctor before taking Xone XP 1.125 gm Injection 5 ml. If you are pregnant or breastfeeding, please inform your doctor before taking Xone XP 1.125 gm Injection 5 ml. Drive only if you are alert as Xone XP 1.125 gm Injection 5 ml may cause dizziness. You are recommended to complete the full course of Xone XP 1.125 gm Injection 5 ml as prescribed by your doctor for effective results. Xone XP 1.125 gm Injection 5 ml may interact with certain tests such as glucose (sugar) in urine and coomb’s test, giving unusual results. Therefore, inform the doctor that you are taking Xone XP 1.125 gm Injection 5 ml before undergoing any tests. If you are on a low-sodium diet or are about to receive calcium-containing products, please inform your doctor before taking Xone XP 1.125 gm Injection 5 ml. 

Drug-Drug Interactions

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CeftriaxoneCalcium chloride
Critical
CeftriaxoneCalcium gluconate
Critical

Drug-Drug Interactions

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CeftriaxoneCalcium chloride
Critical
How does the drug interact with Xone XP 1.125 gm Injection 5 ml:
Co-administration of Calcium chloride with Xone XP 1.125 gm Injection 5 ml can increase the risk of side effects.

How to manage the interaction:
Taking Xone XP 1.125 gm Injection 5 ml with Calcium chloride is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCalcium gluconate
Critical
How does the drug interact with Xone XP 1.125 gm Injection 5 ml:
Co-administration of Calcium gluconate with Xone XP 1.125 gm Injection 5 ml can increase the risk of adverse effects.

How to manage the interaction:
Taking Xone XP 1.125 gm Injection 5 ml with Calcium gluconate is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCholera, live attenuated
Severe
How does the drug interact with Xone XP 1.125 gm Injection 5 ml:
Taking the cholera vaccine after or along with Xone XP 1.125 gm Injection 5 ml may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Xone XP 1.125 gm Injection 5 ml and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. To ensure adequate vaccine response, you should not receive cholera vaccine, live until at least 14 days after you complete your antibiotic therapy. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Xone XP 1.125 gm Injection 5 ml to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Xone XP 1.125 gm Injection 5 ml.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

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Alcohol

Caution

Interaction of Xone XP 1.125 gm Injection 5 ml with alcohol is unknown. Please consult a doctor before consuming alcohol while using Xone XP 1.125 gm Injection 5 ml.

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Xone XP 1.125 gm Injection 5 ml is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

It is unknown whether Xone XP 1.125 gm Injection 5 ml is excreted in human milk. Xone XP 1.125 gm Injection 5 ml is given to breastfeeding mothers if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Xone XP 1.125 gm Injection 5 ml may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Xone XP 1.125 gm Injection 5 ml.

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Liver

Caution

Take Xone XP 1.125 gm Injection 5 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Xone XP 1.125 gm Injection 5 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Xone XP 1.125 gm Injection 5 ml is not recommended for premature and new-born babies up to 28 days who has jaundice or certain blood problems. However, Xone XP 1.125 gm Injection 5 ml is given to children only if prescribed by a doctor.

FAQs

Xone XP 1.125 gm Injection 5 ml is used to treat bacterial infections of the urinary tract, blood, bones and joints, heart, brain, chest, ears, skin, or soft tissues.
Xone XP 1.125 gm Injection 5 ml contains Ceftriaxone and Tazobactum. Ceftriaxone is an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.
Xone XP 1.125 gm Injection 5 ml may interfere with urine test (for sugar) and Coomb’s test (blood test) giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Xone XP 1.125 gm Injection 5 ml.
You are not recommended to take Xone XP 1.125 gm Injection 5 ml with streptomycin as co-administration of these two medicines may increase the risk of kidney damage. However, please consult your doctor before taking Xone XP 1.125 gm Injection 5 ml with other medicines to adjust the dose appropriately.
Xone XP 1.125 gm Injection 5 ml may cause diarrhoea as a common side effect. However, if the condition persists, worsens or notices blood or mucus in stools, avoid taking Xone XP 1.125 gm Injection 5 ml and consult a doctor immediately.
Xone XP 1.125 gm Injection 5 ml is not used to treat viral infections. Xone XP 1.125 gm Injection 5 ml is an antibiotic which is used to treat only bacterial infections.
Xone XP 1.125 gm Injection 5 ml should be used with caution in patients with kidney problems as it may increase the risk of adverse effects. Therefore, inform your doctor if you have any kidney problems before taking Xone XP 1.125 gm Injection 5 ml so that the dose may be adjusted accordingly.
Generally, Xone XP 1.125 gm Injection 5 ml starts working soon after taking it, as it is injected directly into the blood stream. However to kill all the harmful bacteria and make you feel better, it may take some days. So, complete the full course of treatment as prescribed by your doctor.
Inform your doctor if you don't get better after finishing the full course of treatment as prescribed by your doctor. Also, inform if your symptoms are getting worse while using Xone XP 1.125 gm Injection 5 ml.
The common side effects of Xone XP 1.125 gm Injection 5 ml are diarrhoea, rash, raised white blood cells, raised platelets, nausea, vomiting, stomach upset, blood clots, dizziness, headache, a lump where the medicine was injected and sweating. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - XON0004

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