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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:53 PM IST
XONE INJECTION 2GM is used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease). It contains Ceftriaxone, which kills the bacteria and helps in treating bacterial infection. In some cases, it may cause side effects such as diarrhoea, rashes, changes in results of blood and liver tests, and abnormalities (increase/decrease) in the number of white blood cells and platelets. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

CEFTRIAXONE-2GM

Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About XONE INJECTION 2GM

XONE INJECTION 2GM is used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body.

XONE INJECTION 2GM contains 'Ceftriaxone', which works by interfering with the formation of bacterial cell walls, thereby killing the bacteria. Thus, XONE INJECTION 2GM helps in treating bacterial infection.

In some cases, XONE INJECTION 2GM may cause side effects such as diarrhoea, rashes, changes in results of blood and liver tests, and abnormalities (increase/decrease) in the number of white blood cells and platelets. Although not everybody experiences these side effects, if they occur, consult your doctor.

Talk to your doctor before taking XONE INJECTION 2GM if you have/had received calcium-containing products recently, had diarrhoea after taking antibiotics, inflammation of the bowel, kidney stones, or any other illness. Do not take antacids along with XONE INJECTION 2GM; maintain a gap of 2-3 hours between both. Consult your doctor if you are pregnant or breastfeeding. XONE INJECTION 2GM may cause dizziness, so be cautious while driving. Avoid alcohol consumption to prevent unpleasant side effects.

Uses of XONE INJECTION 2GM

Treatment of Bacterial infections

Medicinal Benefits

XONE INJECTION 2GM belongs to the group of antibiotic medicines called cephalosporins used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease). XONE INJECTION 2GM is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and some anaerobic bacteria. XONE INJECTION 2GM works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.

Directions for Use

XONE INJECTION 2GM will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of XONE INJECTION 2GM

  • Diarrhoea
  • Rashes
  • Changes in results of blood and liver tests
  • Abnormalities (increase/decrease) in the number of white blood cells and platelets

Drug Warnings

Before starting XONE INJECTION 2GM, please inform your doctor if you are allergic to any of the components in XONE INJECTION 2GM or against any antibiotic. Talk to your doctor if you have/had received calcium-containing products recently, had diarrhoea after taking antibiotics, inflammation of the bowel, kidney stones, or any other illness. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking XONE INJECTION 2GM to prevent unpleasant side effects. XONE INJECTION 2GM may cause dizziness, so be cautious while driving. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.

Drug Interactions

Drug-Drug Interactions: XONE INJECTION 2GM may interact with a diuretic (furosemide) and antibiotic (chloramphenicol).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), hyperbilirubinemia (excess bilirubin in the blood), gall bladder disease, pancreatitis, seizures, kidney or liver disease.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • CHLORAMPHENICOL

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.

  • Avoid consumption of alcohol and usage of tobacco.

Special Advise

  • XONE INJECTION 2GM might affect the result of diagnostic tests like Coombs’ test (a test for some blood problems), galactosaemia (an abnormal build-up of the sugar galactose), and glucose tests. So tell your doctor that you are taking XONE INJECTION 2GM before undergoing these tests.

  • XONE INJECTION 2GM must not be mixed or administered simultaneously with calcium-containing solutions, including total parenteral nutrition.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause illness. They can target any body part and multiply very quickly. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

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Alcohol

Caution

Avoid consuming alcohol while taking XONE INJECTION 2GM to prevent unpleasant side-effects.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe XONE INJECTION 2GM only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding; your doctor will prescribe XONE INJECTION 2GM only if the benefits outweigh the risks.

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Driving

Caution

XONE INJECTION 2GM may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Safe if prescribed

XONE INJECTION 2GM is safe for children if prescribed by a doctor. XONE INJECTION 2GM is not recommended for a premature baby, or a newborn baby who has jaundice (yellowing of the skin or eyes).

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - XON0019

Author Details

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FAQs

XONE INJECTION 2GM is used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease).
XONE INJECTION 2GM works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.
XONE INJECTION 2GM may cause dizziness, so drive only if you are alert and omit driving and operating machinery if you experience dizziness.
Diarrhoea might be a side-effect of XONE INJECTION 2GM. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
XONE INJECTION 2GM may affect the results of urine tests for sugar and blood test known as coomb’s test (antiglobulin test). Inform the person performing the tests that you are taking XONE INJECTION 2GM.
Do not take antacids along with XONE INJECTION 2GM; maintain a gap of 2-3 hours between both. However, consult your doctor before taking other medicines while on treatment with XONE INJECTION 2GM.
Yes, XONE INJECTION 2GM is generally considered safe when taken in the recommended dose and duration as directed by your doctor. However, sometimes it may cause side effects or allergic reactions in some individuals. Please let your doctor know if any of the side effects bother you.
XONE INJECTION 2GM usually starts working within a few hours after administration. However, XONE INJECTION 2GM may take a few days to show its full effect, depending on the infection being treated. If your symptoms do not improve or get worse, please consult your doctor.
XONE INJECTION 2GM should not be used by individuals who are allergic to its components or other cephalosporin antibiotics. It is also not recommended for use in newborns, especially those with jaundice (yellowing of the skin or eyes).
If you do not feel better after using XONE INJECTION 2GM, it could mean that the infection isn't responding to the antibiotic, or you might have a different type of infection that needs a different treatment. Please consult your doctor for further evaluation and to discuss possible changes to your treatment plan.
XONE INJECTION 2GM is usually eliminated from the body within 5 to 9 hours in healthy individuals. However, XONE INJECTION 2GM may stay in the body for longer depending on the individual's medical condition.
Yes, XONE INJECTION 2GM is effective against a wide range of bacterial infections, including respiratory, urinary tract, skin, and bloodstream infections.
XONE INJECTION 2GM will be administered either intravenously (IV) or intramuscularly (IM), depending on the condition being treated, by your healthcare provider. Please do not self-administer.
No, you should complete the full course of treatment with XONE INJECTION 2GM as prescribed by your doctor, even if you feel better. Please consult your doctor before stopping the medication early, as your infection may not be completely treated and the bacteria may become resistant to the antibiotics.
If you are allergic to Cefuroxime, there is a possible risk of an allergic reaction to XONE INJECTION 2GM, since both are in the same group of antibiotics (cephalosporins). Please consult your healthcare provider before taking XONE INJECTION 2GM or any other cephalosporin antibiotics to ensure safety.
Before starting XONE INJECTION 2GM, you should inform your doctor if you have recently received calcium-containing products, have had diarrhoea after taking antibiotics, or have a history of colitis (inflammation of the large intestine), malnutrition (inability to consume or digest essential nutrients), problems with vitamin K levels, or kidney or liver disease.
No, XONE INJECTION 2GM should only be administered by a healthcare professional, as it requires proper injection technique and monitoring for potential side effects. Please do not administer XONE INJECTION 2GM at home.

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