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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Xolabin 7.5 Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Xolabin 7.5 Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Whats That

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Synonym :

POLYMYXIN B SULPHATE

Manufacturer/Marketer :

Fusion Health Care Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Xolabin 7.5 Injection

Xolabin 7.5 Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Xolabin 7.5 Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Xolabin 7.5 Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Xolabin 7.5 Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Xolabin 7.5 Injection

Treatment of Bacterial infections

Directions for Use

Xolabin 7.5 Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Xolabin 7.5 Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Xolabin 7.5 Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Xolabin 7.5 Injection Works

Xolabin 7.5 Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Xolabin 7.5 Injection

  • Flushing
  • Diarrhoea
  • Dizziness
  • Pain at the injection site

What if I have taken an overdose of Xolabin 7.5 Injection

As Xolabin 7.5 Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Xolabin 7.5 Injection if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Polymyxin bVecuronium
Severe
Polymyxin bHuman immunoglobulin
Severe

Drug-Drug Interactions

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Polymyxin bVecuronium
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Co-administration of Xolabin 7.5 Injection 1's and Vecuronium together may cause serious breathing problems.

How to manage the interaction:
Taking Xolabin 7.5 Injection 1's with Vecuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing difficulty, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bHuman immunoglobulin
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Taking Human immunoglobulin with Polymyxin- b, may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Xolabin 7.5 Injection 1's together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Polymyxin bPancuronium
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Taking Xolabin 7.5 Injection 1's with Pancuronium together can cause breathing problems.

How to manage the interaction:
Taking Xolabin 7.5 Injection 1's with Pancuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing problems, consult a doctor. Do not discontinue any medications without consulting a doctor.
Polymyxin bSuxamethonium
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Taking Xolabin 7.5 Injection 1's with Suxamethonium together may cause serious breathing problems.

How to manage the interaction:
Co-administration of Suxamethonium with Xolabin 7.5 Injection 1's can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bCholera, live attenuated
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Taking Xolabin 7.5 Injection 1's and Cholera together may lead to a decrease in the effectiveness of the vaccine.

How to manage the interaction:
There may be a possibility of interaction between Xolabin 7.5 Injection 1's and Cholera, live attenuated, but it can be taken if prescribed by a doctor. It is advised not to receive the cholera vaccination until at least 14 days after finishing your Xolabin 7.5 Injection 1's therapy in order to ensure an appropriate immune response. Do not discontinue any medications without a doctor's advice.
Polymyxin bBacitracin
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Taking Xolabin 7.5 Injection 1's and Bacitracin together can increase the risk of kidney and inner ear damage

How to manage the interaction:
Although taking Xolabin 7.5 Injection 1's and Bacitracin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience ringing in the ears, hearing loss, vertigo, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bStreptomycin
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Using Xolabin 7.5 Injection 1's together with streptomycin can increase the risk or severity of developing hearing loss, breathing problems, and kidney problems.

How to manage the interaction:
Although taking Xolabin 7.5 Injection 1's and Streptomycin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medication without consulting a doctor.
Polymyxin bNeomycin
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
When Neomycin and Xolabin 7.5 Injection 1's are taken together, there is an increased possibility of severe side effects.

How to manage the interaction:
Taking Xolabin 7.5 Injection 1's with Neomycin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bSuxamethonium
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Co-administration of Xolabin 7.5 Injection 1's may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Xolabin 7.5 Injection 1's can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
Polymyxin bTacrolimus
Severe
How does the drug interact with Xolabin 7.5 Injection 1's:
Taking Tacrolimus with Xolabin 7.5 Injection 1's may increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Xolabin 7.5 Injection 1's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Xolabin 7.5 Injection Substitute

Substitutes safety advice
  • Polygetz XL 750000IU Injection

    3441.54per tablet
  • Polycad-B 7,50,000IU Injection 1's

    4700.00per tablet
  • Pobix 750000IU Injection 1's

    5929.00per tablet
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Xolabin 7.5 Injection. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Xolabin 7.5 Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Xolabin 7.5 Injection. Caution is advised while administering Xolabin 7.5 Injection to lactating women.

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Driving

Consult your doctor

It is unknown if Xolabin 7.5 Injection affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Xolabin 7.5 Injection.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Xolabin 7.5 Injection.

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Children

Safe if prescribed

Xolabin 7.5 Injection may be safe for use in children if prescribed by the doctor.

FAQs

Xolabin 7.5 Injection is used to treat Bacterial infections.
Xolabin 7.5 Injection works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.
Diarrhoea might be a side effect of Xolabin 7.5 Injection. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.
Xolabin 7.5 Injection may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.
Xolabin 7.5 Injection will be administered by a healthcare professional. Do not self-administer.
Yes, Xolabin 7.5 Injection is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.
The common side effects of Xolabin 7.5 Injection may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - XOL0021

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