Xofen 16mg Tablet SR

Xofen 16mg Tablet SR belongs to a group of medicines called anti-rheumatic and anti-inflammatory agents used to reduce and relieve pain and inflammation (swelling) in osteoarthritis and rheumatoid arthritis. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.

Xofen 16mg Tablet SR contains 'Lornoxicam' which works by blocking the effect of chemical messengers that cause pain and inflammation. Thereby, Xofen 16mg Tablet SR helps relieve pain and inflammation associated with rheumatoid arthritis and osteoarthritis.

You are advised to take Xofen 16mg Tablet SR for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience common side-effects such as dizziness, diarrhoea, nausea, headache, vomiting, stomach upset and abdominal pain. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side-effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Xofen 16mg Tablet SR should not be taken during the last three months of pregnancy. Xofen 16mg Tablet SR may cause dizziness, so drive only if you are alert. Xofen 16mg Tablet SR is not recommended for children below 18 years as safety has not been established. It is not known if alcohol affects Xofen 16mg Tablet SR. Please consult your doctor if you have any concerns. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Xofen 16mg Tablet SR belongs to a group of medicines called anti-rheumatic and anti-inflammatory agents. Xofen 16mg Tablet SR is used to reduce and relieve pain and inflammation (swelling) in osteoarthritis and rheumatoid arthritis. Xofen 16mg Tablet SR works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Thereby, Xofen 16mg Tablet SR helps to relieve pain and inflammation associated with osteoarthritis and rheumatoid arthritis.

• Headache
• Dizziness
• Nausea
• Abdominal pain
• Stomach upset
• Diarrhoea
• Vomiting

Do not take Xofen 16mg Tablet SR if you are allergic to any of its components, if you have thrombocytopenia (low levels of platelets), gastrointestinal or other bleeding problems, peptic ulcers, severe heart, liver or kidney problems, if you have a history of gastrointestinal bleeding or perforation problems with NSAID's. Inform your doctor if you have impaired kidney or liver function, high blood pressure, heart failure, ulcerative colitis or Crohn's disease, asthma, lupus erythematosus (auto-immune disease), diabetes, or blood coagulation disorder. Consult your doctor if you are pregnant or breastfeeding. Xofen 16mg Tablet SR should not be taken during the last three months of pregnancy. Xofen 16mg Tablet SR may cause dizziness, so drive only if you are alert. Xofen 16mg Tablet SR is not recommended for children below 18 years as safety has not been established. Stop taking Xofen 16mg Tablet SR and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools.

Drug-Drug Interactions: Xofen 16mg Tablet SR may interact with a blood thinner (warfarin, heparin, phenprocoumon), immunosuppressant (tacrolimus, cyclosporine), pain killers (aspirin), antacid (cimetidine), anti-rheumatoid (methotrexate), anti-psychotic (lithium), cardiac glycoside (digoxin), anti-diabetic (glibenclamide), antibiotic (rifampicin), anti-fungal (fluconazole), anti-cancer (pemetrexed), diuretics, ACE inhibitors, beta-adrenergic blocking agents, anti-depressants, and corticosteroids.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have thrombocytopenia (low levels of platelets), gastrointestinal or other bleeding problems, peptic ulcers, high blood pressure, heart failure, ulcerative colitis or Crohn's disease, asthma, lupus erythematosus (auto-immune disease), diabetes, blood coagulation disorder, impaired heart, kidney or liver function.

• WARFARIN
• HEPARIN
• PHENPROCOUMON
• TACROLIMUS
• CYCLOSPORINE
• ASPIRIN
• CIMETIDINE
• METHOTREXATE
• LITHIUM
• DIGOXIN
• GLIBENCLAMIDE
• RIFAMPICIN
• FLUCONAZOLE
• PEMETREXED

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Acupuncture, massage and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
• Avoid smoking and alcohol consumption.

• Your doctor may regularly monitor your condition if you have blood coagulation disorder, impaired liver function or if you are elderly or have been prescribed Xofen 16mg Tablet SR for more than 3 months.

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of a protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function.