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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:22 PM IST
Xibrocin 1000mg Injection is an antibiotic used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), and osteomyelitis (infection of the bone). It contains Vancomycin, which prevents the formation of bacterial protective covering (cell wall) needed for their survival. Thus, it kills bacteria.
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Prescription drug

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Manufacturer/Marketer

Brawn Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Xibrocin 1000mg Injection

Xibrocin 1000mg Injection belongs to a class of antibiotics called glycopeptide, primarily used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), and osteomyelitis (infection of the bone). Bacterial infection occurs when harmful bacteria grow in the body and causes illness.

Xibrocin 1000mg Injection is composed of 'Vancomycin'. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive.

Xibrocin 1000mg Injection will be administered by a healthcare professional; do not self-administer it. Common side effects of Xibrocin 1000mg Injection are application site reactions like pain, redness, and swelling. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you have liver/kidney diseases, hearing problems, and stomach/intestinal disorders before starting Xibrocin 1000mg Injection. Do not use Xibrocin 1000mg Injection while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Xibrocin 1000mg Injection may affect vaccines' activity. Pregnant and breastfeeding women should consult the doctor before starting Xibrocin 1000mg Injection. Avoid alcohol consumption to prevent any undesired effects while using Xibrocin 1000mg Injection. Xibrocin 1000mg Injection should be used for children only when prescribed by a doctor, depending on the child's age and body weight.

Uses of Xibrocin 1000mg Injection

Treatment of Bacterial Infections.

Medicinal Benefits

Xibrocin 1000mg Injection is composed of 'Vancomycin'. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) needed to survive. Xibrocin 1000mg Injection used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), osteomyelitis (infection of the bone), endocarditis (infection of the inner lining of the heart ), skin and soft tissue infection, surgical prophylaxis (infections during surgery) and lower respiratory tract infections.

Directions for Use

It will be injected by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Xibrocin 1000mg Injection

  • Pain
  • Redness
  • Swelling at the injection site

Drug Warnings

Let your doctor know if you are allergic reactions to any medicines. Some rare cases may cause serious side effects like hearing problems (such as ringing in the ears, and hearing loss) and signs of kidney problems (such as a change in the amount of urine), please stop using the medicine in such cases and consult your doctor immediately. Do not use Xibrocin 1000mg Injection while getting vaccinated with live bacterial vaccines (typhoid vaccine) since Xibrocin 1000mg Injection may affect vaccines' activity. Pregnant and breastfeeding women should consult their doctor before taking Xibrocin 1000mg Injection. Avoid alcohol consumption to prevent any undesired effects while using Xibrocin 1000mg Injection. Xibrocin 1000mg Injection should be used for children only when prescribed by a doctor, depending on the child's age and body weight.

Drug Interactions

Drug-Drug Interaction: Xibrocin 1000mg Injection may interact with antibiotics (amikacin, gentamicin, bacitracin),  blood thinner (enoxaparin, warfarin), diuretics  (furosemide), anti-diabetics (metformin, insulin-glargine), vaccines (cholera vaccine, typhoid vaccine), oestrogen (ethinylestradiol), pain killers (ketorolac), and antacids (pantoprazole).

Drug-Food Interaction: Avoid fatty foods, alcohol, and caffeine with Xibrocin 1000mg Injection. 

Drug-Disease Interaction: Inform your doctor if you have colitis, ototoxicity/hearing problems, kidney dysfunction, neutropenia (abnormally low count of a type of white blood cell (neutrophils), and gastrointestinal inflammation.

Drug-Drug Interactions Checker List

  • CHOLERA VACCINE
  • TYPHOID VACCINE
  • AMIKACIN
  • GENTAMICIN
  • BACITRACIN
  • ENOXAPARIN
  • WARFARIN
  • FUROSEMIDE
  • INSULIN GLARGINE
  • METFORMIN
  • ETHINYLESTRADIOL
  • KETOROLAC
  • PANTOPRAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Taking probiotics after an antibiotic treatment reduces the risk of antibiotic-associated diarrhoea. 
  • Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as it can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Special Advise

Your doctor may regularly monitor your kidney function and hearing while taking this medicine.

Disease/Condition Glossary

Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod and spiral-shaped. Bacteria may be gram-positive (have a thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever, shortness of breath, chills, muscle pain, fatigue, and tiredness. Untreated bacterial infections may lead to serious life-threatening conditions like sepsis.

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Alcohol

Caution

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

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Pregnancy

Caution

Please consult your doctor before taking Xibrocin 1000mg Injection if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Xibrocin 1000mg Injection can be excreted into breast milk when used by a nursing mother. Please consult your doctor before taking Xibrocin 1000mg Injection if you are breastfeeding.

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Driving

Caution

There is limited data on how Xibrocin 1000mg Injection affects your driving ability. Please seek medical advice for more information.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Xibrocin 1000mg Injection. However, it is not recommended in patients with severe liver diseases.

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Kidney

Caution

Let your doctor know if you have any history of kidney problems. Your doctor will weigh the benefits and potential risks before prescribing Xibrocin 1000mg Injection. However, it is not recommended in patients with severe kidney diseases.

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Children

Caution

Xibrocin 1000mg Injection should be used for children only when prescribed by a doctor, depending on the child's age and body weight.

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Author Details

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FAQs

Xibrocin 1000mg Injection is used to treat severe bacterial infections in hospitalised patients. It is effective against bacterial infections like ulcerative colitis (chronic inflammation of the colon), bacterial septicemia (infection of the blood caused by bacteria), and osteomyelitis (infection of the bone).
Xibrocin 1000mg Injection contains Vancomycin which kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive.
Xibrocin 1000mg Injection can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor before you start Xibrocin 1000mg Injection if you are undergoing any vaccinations.
Diarrhoea can be a side-effect of Xibrocin 1000mg Injection. Clostridium difficile-associated diarrhoea (CDAD) is also reported during the usage of antibiotics like Xibrocin 1000mg Injection. Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Xibrocin 1000mg Injection therapy.
While using Xibrocin 1000mg Injection, caution should be exercised for patients with a history of kidney impairment, hearing problems, newborns, and the elderly population.
Yes, Xibrocin 1000mg Injection is an antibiotic. It contains vancomycin as its active ingredient, which belongs to the class of medications called glycopeptide antibiotics.
The dose of Xibrocin 1000mg Injection varies depending on the severity of the infection and the patient's condition. However, your doctor will determine the exact dose and duration based on your specific condition. Do not self-administer.
Xibrocin 1000mg Injection typically starts working soon after intravenous infusion. However, it may take a few days to notice significant improvement in symptoms. It's important to complete the full course of treatment as prescribed by your doctor.
The common side effects of Xibrocin 1000mg Injection are pain, redness, and swelling at the injection site. If any of these side effects persist or worsen, please consult your doctor.

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