apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:07 PM IST
Xeloda 500 mg Tablet is used to treat breast, colon and stomach cancer. It contains Capecitabine which works by interfering with the growth of cancer cells. In some cases, this medicine may cause side effects such as nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, and mouth ulcers. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Xeloda 500 mg Tablet

Xeloda 500 mg Tablet is used to treat breast, colon and stomach cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one body part before spreading to other areas. This process is known as metastasis.

Xeloda 500 mg Tablet contains Capecitabine, an anti-cancer medication that is cytotoxic (causes cell death). When taken, it gets converted into 5-fluorouracil (chemical), which hampers the synthesis of genetic materials (DNA) in the cancer cells, thereby interfering with their growth. As a result, cancer cells' growth is slowed down and eventually killed.

You may experience certain common side-effects such as nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells (red cells, white cells, and platelets), mouth ulcers, blisters on fingers/feet in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Xeloda 500 mg Tablet , inform your doctor if you have any infection because Xeloda 500 mg Tablet may worsen the infection. Some patients may experience increased sensitivity to light while taking Xeloda 500 mg Tablet ; avoiding prolonged exposure to sunlight is recommended. Inform your doctor if you are pregnant as Xeloda 500 mg Tablet can cause harmful effects on the unborn baby. Both women and men using Xeloda 500 mg Tablet should use birth control to avoid pregnancy. You should not take Xeloda 500 mg Tablet during breastfeeding. Use Xeloda 500 mg Tablet with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy. You and your surrounding people, such as family members, should not take the polio vaccine.

Uses of Xeloda 500 mg Tablet

Treatment of Breast cancer, stomach, rectal and colon cancer.

Medicinal Benefits

Xeloda 500 mg Tablet belongs to the group of anti-cancer medicines. It contains Capecitabine which is cytotoxic (causes cell death). It is used to treat cancer of the colon, breast and stomach. When taken, it gets converted into 5-fluorouracil (chemical), which hampers the synthesis of genetic materials (DNA) in the cancer cells, thereby interfering with their growth. As a result, the growth of cancer cells is slowed down, and eventually, they are killed.

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Xeloda 500 mg Tablet

  • Nausea
  • Vomiting
  • Weakness
  • Loss of appetite
  • Increased risk of infection
  • Hair loss
  • Diarrhoea
  • Decreased blood cells 
  • Mouth ulcer
  • Blisters on fingers/feet

Drug Warnings

Before taking Xeloda 500 mg Tablet , inform your doctor if you have any infection because Xeloda 500 mg Tablet may worsen the infection. If you have any allergy symptoms, talk to your doctor; inform your doctor if you have a metabolic disorder called DPD (dihydropyrimidine dehydrogenase deficiency), heart problems, bone marrow depression, kidney disease, liver disease, and treatment with chemotherapy or radiation. Some patients may experience increased sensitivity to light while taking Xeloda 500 mg Tablet , and avoiding prolonged exposure to sunlight is recommended. Consult your doctor if you are pregnant as Xeloda 500 mg Tablet can cause harmful effects on the unborn baby. Both women and men using Xeloda 500 mg Tablet should use birth control to avoid pregnancy. The use of Xeloda 500 mg Tablet by either parent may result in congenital disabilities. You should not take Xeloda 500 mg Tablet during breastfeeding. Use Xeloda 500 mg Tablet with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy. You and your surrounding people, such as family members, should not take the polio vaccine. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Xeloda 500 mg Tablet catches fire and burns easily. Washing clothing and bedding may reduce product build-up but not remove it.

Drug Interactions

Drug-Drug Interactions: Xeloda 500 mg Tablet interacts with other anti-cancer medicines (folinic acid, oxaliplatin, bevacizumab, cisplatin, irinotecan), antibiotics (metronidazole), medicines used to reduce the harmful effects of anti-cancer medicines (calcium leucovorin), a medicine used to treat gout (allopurinol), a medicine used to treat stomach ulcers (cimetidine), blood thinners (warfarin, coumarin), antivirals (brivudine, sorivudine), and anti-epilepsy medicine (phenytoin).

Drug-Food Interactions: Xeloda 500 mg Tablet is known to interact with alcohol and increase dizziness.

Drug-Disease Interactions: Xeloda 500 mg Tablet should not be given to patients with liver, heart or kidney problems, diabetes, glaucoma (increased eye pressure), myelosuppression (bone marrow activity is decreased), dihydropyrimidine dehydrogenase (DPD) enzyme deficiency, stomatitis, infections, or a bleeding disorder.

Drug-Drug Interactions Checker List

  • BEVACIZUMAB
  • CISPLATIN
  • METRONIDAZOLE
  • CALCIUM LEUCOVORIN
  • ALLOPURINOL
  • CIMETIDINE
  • WARFARIN
  • COUMARINS
  • BRIVUDINE
  • SORIVUDINE
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.

  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

  • Get optimal sleep; rest well.

Special Advise

  • Regularly monitor your blood tests to monitor your liver function, electrolyte levels, and blood cell count in your blood.

  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Xeloda 500 mg Tablet may make your skin sensitive to sunlight.

  • Xeloda 500 mg Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Xeloda 500 mg Tablet .

  • Consult a doctor immediately if you notice any signs of infection, fever, diarrhoea, chills, etc.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts. Symptoms of breast cancer include a lump in the breast or tissue thickening, which feels different than the normal surrounding tissues, breast pain, redness, swelling, and nipple discharge other than breast milk.

Stomach cancer (gastric cancer): It is a type of cancer that develops from the stomach lining. Risk factors may include smoking, a highly processed or salty diet, and severe bacterial infection of H. pylori. Symptoms of stomach cancer include feeling bloated after eating, feeling full after eating small amounts of food, nausea, heartburn or indigestion.

bannner image

Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Xeloda 500 mg Tablet to avoid unpleasant side effects. Alcohol intake, along with Xeloda 500 mg Tablet , may cause increased drowsiness.

bannner image

Pregnancy

Unsafe

Xeloda 500 mg Tablet should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking fluorouracil and for at least six months afterwards. Please consult your doctor about any concerns regarding this.

bannner image

Breast Feeding

Unsafe

Xeloda 500 mg Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

bannner image

Driving

Unsafe

Xeloda 500 mg Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Xeloda 500 mg Tablet . Your doctor will weigh the benefits and potential risks before prescribing Xeloda 500 mg Tablet .

bannner image

Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Xeloda 500 mg Tablet . Your doctor will weigh the benefits and potential risks before prescribing Xeloda 500 mg Tablet .

bannner image

Children

Unsafe

Xeloda 500 mg Tablet should not be used by children, as efficacy and safety have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Other Info - XEL0002

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Xeloda 500 mg Tablet belongs to a group of medicines known as 'anti-cancer' used to treat breast, colon and stomach cancer.
Xeloda 500 mg Tablet interferes with the growth of the cancer cells' genetic material (DNA). This slows the growth of cancer cells and eventually kills them.
Xeloda 500 mg Tablet can make your skin more sensitive to the harmful effects of sunlight. Hence it is advised to wear protective clothing while using Xeloda 500 mg Tablet . It is recommended to avoid tanning booths and sunlamps.
Yes, Xeloda 500 mg Tablet may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking Xeloda 500 mg Tablet as regular monitoring of liver and kidney functions tests, electrolyte levels and blood cells is required.
Xeloda 500 mg Tablet might affect fertility (ability to have children) in both men and women. You may not be able to become pregnant or father a child after treatment with Xeloda 500 mg Tablet . However, it is essential to talk to your doctor before starting treatment with Xeloda 500 mg Tablet if you think you may want to have a baby in the future.
Yes, Xeloda 500 mg Tablet commonly affects the hair by making it thin, which further causes hair loss. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Xeloda 500 mg Tablet . These effects are not long-lasting and may return after some time. If it matters to you, then consult your doctor for further advice.
Xeloda 500 mg Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Xeloda 500 mg Tablet .
Your doctor will decide the number of treatment cycles and the frequency of Xeloda 500 mg Tablet to be taken, depending on the type and stage of the cancer being treated.
No, it is advised not to use these two medicines at the same time as they may cause severe drug reactions. Maintain a gap of at least four weeks between the last dose of brivudine and the first dose of Xeloda 500 mg Tablet .
Xeloda 500 mg Tablet contains Capecitabine, an anti-cancer medication used to treat breast cancer, stomach, rectal and colon cancer.
Xeloda 500 mg Tablet may cause side-effects such as nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells (red cells, white cells, and platelets), mouth ulcers, blisters on fingers/feet in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Add to Cart