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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Vpl 5 mg Injection 10 x 2 ml is used to treat abnormal heart rhythms (arrhythmia), such as an irregular or rapid heart rate. It can also treat high blood pressure (hypertension) and heart failure. It contains Verapamil. It works by relaxing the blood vessels, decreasing the workload on the heart. It also increases the blood and oxygen supply to the heart, normalizing electrical impulses. These effects help reduce blood pressure and control the rate and rhythm of the heartbeat.
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Prescription drug

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Synonym

VERAPAMIL HYDROCHLORIDE

Composition

VERAPAMIL-5MG

Manufacturer/Marketer

Samarth Life Sciences Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Vpl 5 mg Injection 10 x 2 ml

Vpl 5 mg Injection 10 x 2 ml belongs to the class of medications called calcium channel blockers used to treat abnormal heart rhythms (arrhythmia) such as an irregular or rapid heart rate. On the other hand, it can also use to treat high blood pressure (hypertension) and heart failure. Arrhythmia is a condition in which your heart beats irregularly, too fast or too slow. Hypertension is a condition in which there is a persistent rise in blood pressure levels.

Vpl 5 mg Injection 10 x 2 ml contains Verapamil. It works by relaxing the blood vessels decreasing the workload on the heart. It also increases the blood and oxygen supply to the heart, thereby normalizing the electrical signals. These effects help to reduce blood pressure and also control the rate and rhythm of the heartbeat.

Vpl 5 mg Injection 10 x 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, Vpl 5 mg Injection 10 x 2 ml may cause side effects such as injection site reactions, hypotension (low blood pressure), feeling dizzy or lightheaded, headaches, diarrhoea and being sick (vomiting). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before taking the Vpl 5 mg Injection 10 x 2 ml , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Vpl 5 mg Injection 10 x 2 ml can cause blurred vision and dizziness in some people, especially when they first start taking it or after a higher dose. If this occurs, do not drive a car, ride a bike, or operate tools or machinery. Do not consume any alcoholic beverages if you have heart problems.

Uses of Vpl 5 mg Injection 10 x 2 ml

Treatment of Arrhythmias and Hypertension

Medicinal Benefits

Vpl 5 mg Injection 10 x 2 ml contains Verapamil. It works by relaxing the blood vessels decreasing the workload on the heart. It also increases the blood and oxygen supply to the heart, normalizing electrical impulses. These effects help reduce blood pressure and control the rate and rhythm of the heartbeat.

Directions for Use

Vpl 5 mg Injection 10 x 2 ml will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Vpl 5 mg Injection 10 x 2 ml

  • Nausea
  • Constipation
  • Headache
  • Dizziness
  • Low blood pressure
  • A dry, tickly cough
  • Feeling dizzy or lightheaded
  • Headaches
  • Diarrhoea
  • Vomiting
  • A mild skin rash
  • Blurred vision

Drug Warnings

Before taking the Vpl 5 mg Injection 10 x 2 ml , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you have low blood pressure, kidney impairment, abnormally slow or irregular heartbeat, history of heart failure, or a heart condition called Wolff-Parkinson-White syndrome, myasthenia gravis (muscle disorders) or if you are treated with Ivabradine (medicine for a heart condition). And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Vpl 5 mg Injection 10 x 2 ml can cause blurred vision and dizziness in some people, especially when they first start taking it or after a higher dose. If this occurs, do not drive a car, ride a bike, or operate tools or machinery. It is recommended not to consume any alcoholic beverages.

Drug Interactions

Drug-Drug Interactions: Vpl 5 mg Injection 10 x 2 ml may interact with medicines used to treat heart diseases (e.g. ivabradine, digoxin), medicines used to treat high blood pressure (e.g. atenolol, propranolol), medicines used to lower cholesterol levels (e.g. simvastatin, atorvastatin), medicines used to treat arrhythmias (e.g. quinidine, flecainide), anticoagulant (e.g. dabigatran), antidepressants (e.g. lithium, imipramine), immunosuppressants (e.g. ciclosporin, tacrolimus), a medicine used to treat diabetes (e.g. glibenclamide), pain killer (e.g. aspirin), medicines used to treat migraine (e.g. almotriptan), a medicine used to treat stomach ulcers (e.g. cimetidine), medicines used to treat epilepsy (e.g. phenobarbital, carbamazepine), medicines used to treat infections (e.g. rifampicin, erythromycin), a medicine used to treat HIV (e.g. ritonavir), sedative (e.g. midazolam), and medicines used to treat gout (e.g. colchicine, sulfinpyrazone).

Drug-Food Interactions: Do not take grapefruit or juice as it may increase the effects of Vpl 5 mg Injection 10 x 2 ml .

Drug-Disease Interactions: Vpl 5 mg Injection 10 x 2 ml may interact with disease conditions including low blood pressure, kidney impairment, abnormally slow or irregular heartbeat, history of heart failure, or a heart condition called Wolff-Parkinson-White syndrome, Muscle disorders (such as myasthenia gravis, Lambert-Eaton syndrome).

Drug-Drug Interactions Checker List

  • IVABRADINE
  • DIGOXIN
  • ATENOLOL
  • PROPRANOLOL
  • SIMVASTATIN
  • QUINIDINE
  • FLECAINIDE
  • IMIPRAMINE
  • CICLOSPORIN
  • TACROLIMUS
  • GLIBENCLAMIDE
  • ASPIRIN
  • ALMOTRIPTAN
  • CIMETIDINE
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • RIFAMPICIN
  • ERYTHROMYCIN
  • RITONAVIR
  • MIDAZOLAM
  • COLCHICINE
  • SULFINPYRAZONE
  • CLARITHROMYCIN

Habit Forming

No

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Special Advise

  • Let your doctor know that you are taking Vpl 5 mg Injection 10 x 2 ml if you are scheduled for surgery where an anaesthetic will be used (including dental treatment).
  • Vpl 5 mg Injection 10 x 2 ml may cause low blood pressure and dizziness, so rise slowly from sitting or lying. 
  • Please do not stop taking the medication without discussing it with your doctor. 

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

Arrhythmia: Arrhythmia is a condition in which your heart beats irregularly, too fast, or too slow. Symptoms of irregular heartbeat include chest pain, shortness of breath, and fast or slow heartbeat. 60 to 100 beats per minute generally are considered a normal heart rate.

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Alcohol

Unsafe

Do not consume alcohol while using Vpl 5 mg Injection 10 x 2 ml as it may worsen your condition.

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Pregnancy

Caution

Vpl 5 mg Injection 10 x 2 ml should be used with caution in pregnancy as it may harm your unborn baby. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

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Breast Feeding

Caution

Vpl 5 mg Injection 10 x 2 ml should not be used in nursing mothers unless necessary. So, inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

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Driving

Caution

Vpl 5 mg Injection 10 x 2 ml may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after taking this medicine.

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Liver

Caution

Inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you have a pre-existing or a history of liver disease/condition. Your doctor may adjust the dose depending on your current liver condition.

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Kidney

Caution

Inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you have a pre-existing or a history of kidney disease/condition. Your doctor may adjust the dose depending on your current medical condition.

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Children

Safe if prescribed

Please consult your paediatrician. Your child's doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - VPL0001

Author Details

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FAQs

Vpl 5 mg Injection 10 x 2 ml is used to treat Arrhythmias and Hypertension.
Vpl 5 mg Injection 10 x 2 ml contains Verapamil, which belongs to the class of calcium channel blockers. It works by relaxing the blood vessels making the blood flow easy. It also increases the blood and oxygen supply to the heart. These effects help reduce blood pressure and control the rate and rhythm of the heartbeat.
It is not recommended to take Vpl 5 mg Injection 10 x 2 ml with other medicines to treat high blood pressure, especially beta-blockers such as atenolol, propranolol, and metoprolol. It may cause an atrioventricular block (a type of heart block) and bradycardia (slow heart rate).
Vpl 5 mg Injection 10 x 2 ml is not suitable for patients with myasthenia gravis (muscle disorders); if you are suffering from myasthenia gravis, inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml .
Vpl 5 mg Injection 10 x 2 ml is contraindicated in people using Ivabradine. So, inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you are on treatment with Ivabradine.
Vpl 5 mg Injection 10 x 2 ml should not be taken in people with any degree of heart failure (unless you have a pacemaker), who are taking beta-blockers, who have severe hypotension (low blood pressure), who have severe bradycardia (low heart rate), and Wolff-Parkinson-White syndrome (rapid heart rate associated with dizziness).

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