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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
VPARIN 25000I.U INJECTION is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

HEPARIN-25000I.U

Manufacturer/Marketer :

Vh Bhagat & Company

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About VPARIN 25000I.U INJECTION

VPARIN 25000I.U INJECTION belongs to a class of drugs called anticoagulants or blood thinners. VPARIN 25000I.U INJECTION is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. VPARIN 25000I.U INJECTION works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

VPARIN 25000I.U INJECTION will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of VPARIN 25000I.U INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to VPARIN 25000I.U INJECTION or any other medicines, please tell your doctor. It is not known whether VPARIN 25000I.U INJECTION harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using VPARIN 25000I.U INJECTION. VPARIN 25000I.U INJECTION is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking VPARIN 25000I.U INJECTION.

Uses of VPARIN 25000I.U INJECTION

Prevention of blood clots.

Directions for Use

VPARIN 25000I.U INJECTION will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

VPARIN 25000I.U INJECTION is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). VPARIN 25000I.U INJECTION also reduces the risk of blood clots during surgeries (like heart surgery). VPARIN 25000I.U INJECTION is used as an anticoagulant in blood transfusion and in a dialysis procedure.

How VPARIN 25000I.U INJECTION Works

VPARIN 25000I.U INJECTION works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of VPARIN 25000I.U INJECTION

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

What if I have taken an overdose of VPARIN 25000I.U INJECTION

The overdose of VPARIN 25000I.U INJECTION is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with VPARIN 25000I.U INJECTION, please inform your doctor immediately.

Drug Warnings

Use VPARIN 25000I.U INJECTION cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving VPARIN 25000I.U INJECTION. Patients should inform the doctor that they are receiving VPARIN 25000I.U INJECTION before any surgery is scheduled.

Drug-Drug Interactions

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HeparinBazedoxifene
Critical
HeparinAlteplase
Critical

Drug-Drug Interactions

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HeparinBazedoxifene
Critical
How does the drug interact with VPARIN 25000I.U INJECTION:
When VPARIN 25000I.U INJECTION is taken with bazedoxifene the effects of VPARIN 25000I.U INJECTION are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with VPARIN 25000I.U INJECTION is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinAlteplase
Critical
How does the drug interact with VPARIN 25000I.U INJECTION:
Taking Alteplase with VPARIN 25000I.U INJECTION can increase the risk of bleeding.

How to manage the interaction:
Taking VPARIN 25000I.U INJECTION with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinTiclopidine
Critical
How does the drug interact with VPARIN 25000I.U INJECTION:
Taking Ticlopidine with VPARIN 25000I.U INJECTION can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with VPARIN 25000I.U INJECTION is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinTenecteplase
Critical
How does the drug interact with VPARIN 25000I.U INJECTION:
Taking Tenecteplase with VPARIN 25000I.U INJECTION can increase the risk of bleeding.

How to manage the interaction:
Taking VPARIN 25000I.U INJECTION with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with VPARIN 25000I.U INJECTION:
Using VPARIN 25000I.U INJECTION with Oritavancin can make VPARIN 25000I.U INJECTION less effective as a therapy.

How to manage the interaction:
VPARIN 25000I.U INJECTION is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess VPARIN 25000I.U INJECTION's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinMifepristone
Critical
How does the drug interact with VPARIN 25000I.U INJECTION:
Taking Mifepristone with VPARIN 25000I.U INJECTION can increase the risk of negative side effects.

How to manage the interaction:
Taking VPARIN 25000I.U INJECTION with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOmacetaxine mepesuccinate
Severe
How does the drug interact with VPARIN 25000I.U INJECTION:
Taking VPARIN 25000I.U INJECTION with Omacetaxine mepesuccinate can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Omacetaxine mepesuccinate with VPARIN 25000I.U INJECTION can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
HeparinProtamine
Severe
How does the drug interact with VPARIN 25000I.U INJECTION:
When Protamine and VPARIN 25000I.U INJECTION are used together, can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Protamine and VPARIN 25000I.U INJECTION, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
HeparinAbciximab
Severe
How does the drug interact with VPARIN 25000I.U INJECTION:
Taking Abciximab with VPARIN 25000I.U INJECTION may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Abciximab with VPARIN 25000I.U INJECTION can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these signs - bleeding, bruising, vomiting, headache, dizziness, weakness, or blood in your urine or stools, it's important to contact a doctor immediately. Do not stop using any medications without talking to a doctor.
HeparinEdoxaban
Severe
How does the drug interact with VPARIN 25000I.U INJECTION:
Taking Edoxaban with VPARIN 25000I.U INJECTION may increase the risk of bleeding.

How to manage the interaction:
Co-administration of VPARIN 25000I.U INJECTION with Edoxaban can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-25000I.UHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-25000I.UHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking VPARIN 25000I.U INJECTION along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking VPARIN 25000I.U INJECTION.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

VPARIN 25000I.U INJECTION Substitute

Substitutes safety advice
  • THINLA 25000IU INJECTION

    301.50per tablet
  • TROYHEP 25000IU INJECTION 5ML

    60.40per tablet
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with VPARIN 25000I.U INJECTION as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

VPARIN 25000I.U INJECTION is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

VPARIN 25000I.U INJECTION should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

VPARIN 25000I.U INJECTION usually does not affect your ability to drive or operate machinery.

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Liver

Caution

VPARIN 25000I.U INJECTION should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

VPARIN 25000I.U INJECTION should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

VPARIN 25000I.U INJECTION is not recommended for children below 2 months.

FAQs

VPARIN 25000I.U INJECTION is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.
VPARIN 25000I.U INJECTION works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.
No, you are not recommended to take ibuprofen with VPARIN 25000I.U INJECTION as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with VPARIN 25000I.U INJECTION.
Yes, VPARIN 25000I.U INJECTION may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.
Yes, VPARIN 25000I.U INJECTION may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.
Yes, VPARIN 25000I.U INJECTION may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking VPARIN 25000I.U INJECTION to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Country of origin

India
Other Info - VPA0001

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