Vinrel 50mg Injection

Vinrel 50mg Injection belongs to the group of medicines called vinca alkaloids used alone or in combination with other anti-cancer medicines to treat non-small cell lung cancer that has spread to other body parts and advanced breast cancer that has not responded to other medicines.

Vinrel 50mg Injection contains Vinorelbine, which works by stopping or slowing the growth of cancer cells in the body.

In some cases, Vinrel 50mg Injection may cause side effects such as nausea, vomiting, constipation, injection site reactions, and a decrease in white and red blood cells. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Vinrel 50mg Injection if you are pregnant, breastfeeding, or think you may be pregnant. Vinrel 50mg Injection is not recommended for children below 18 years. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Vinrel 50mg Injection belongs to the group of medicines called vinca alkaloids used to treat locally advanced or metastatic non-small cell lung cancer and advanced breast cancer that has not responded to other medicines. It may also be used to treat cancer of the oesophagus and soft tissue sarcoma (cancer that forms in the muscles). Vinrel 50mg Injection contains Vinorelbine, which works by stopping the growth and multiplication of cancer cells. 

• Nausea
• Vomiting
• Constipation
• Injection site reactions like redness, burning pain, inflammation of veins, or vein discolouration
• A decrease in red or white blood cells
• Weakness of lower extremities
• Liver disorders (abnormal liver tests)

Do not use Vinrel 50mg Injection if you are allergic to any of its components, if you are pregnant, think you might be pregnant or breastfeeding, if you have low white blood cell count, have/had a severe infection within two weeks, have thrombocytopenia (low platelet count), or if you have taken or plan to receive yellow fever vaccination. Inform the doctor if you have a history of heart attack, severe chest pain, liver problems, and signs or symptoms of infection. Consult the doctor immediately if you become pregnant during treatment with Vinrel 50mg Injection. Seek immediate medical attention if you experience symptoms of pulmonary embolism (chest pain, breathlessness, and fainting), posterior reversible encephalopathy syndrome (headaches, changed mental state which may lead to confusion and coma, convulsions, blurred vision and high blood pressure), infection (cough, fever, and chills), severe constipation with abdominal pain, acute respiratory distress syndrome (difficulty breathing), severe reduced blood pressure (severe dizziness and lightheadedness when you stand up), severe chest pain, or allergic reactions (dizziness, rash, swelling of the eyelids, face, lips or throat).

Drug-Drug Interactions: Inform the doctor if you are taking anticoagulants, anti-epileptics (phenytoin), antifungals (itraconazole, ketoconazole), anti-cancer (mitomycin C), immunosuppressants (tacrolimus, ciclosporin).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have asthma, severe liver problems, severe infection, or heart problems.

• PHENYTOIN
• ITRACONAZOLE
• KETOCONAZOLE
• MITOMYCIN
• TACROLIMUS
• CICLOSPORIN

• Eat a healthy diet and exercise regularly to maintain proper weight.
• Avoid smoking and alcohol consumption.
• Include vegetables and fruits in your diet.
• Avoid fast, fried, processed meats, refined carbs, and added sugar.
• Get optimal sleep; rest well.
• Drink enough water and eat fibre-rich foods like spinach, lettuce, squashes, broccoli, nuts, seeds, beans, whole wheat pasta, whole wheat bread, brown rice and fruits.

• Your doctor may advise regular blood tests before and during treatment with Vinrel 50mg Injection to check if it is safe for you to receive the treatment.
• Inform the doctor if you are due to take any vaccinations, as many vaccines (live attenuated vaccines) are not recommended during treatment with Vinrel 50mg Injection.
• Women of childbearing potential must use effective contraception during treatment and for seven months after the end of the treatment.
• If you are a man being treated with Vinrel 50mg Injection, discuss with the doctor about sperm conservation. Men are advised to use effective contraception during treatment and for four months after the end of the treatment. 

Non-small cell lung cancer: It is a disease in which cancer cells form in the tissues of the lungs. Smoking is the major risk factor for non-small cell lung cancer. Symptoms include a cough that does not go away and shortness of breath.

Breast cancer: It is a type of cancer that develops in the breast when the cells grow abnormally. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.