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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

Vinrel 50mg Injection is used to treat non-small cell lung cancer. It contains Vinorelbine, which works by stopping or slowing the growth of cancer cells in the body. This medication is recommended not to use if you are allergic to any of its components, if you are pregnant, think you might be pregnant or breastfeeding, if you have a low white blood cell count, have/had a severe infection within two weeks, have thrombocytopenia (low platelet count), or if you have taken or plan to receive yellow fever vaccination.

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Composition

VINORELBINE-50MG

Manufacturer/Marketer

Khandelwal Laboratories Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Vinrel 50mg Injection

Vinrel 50mg Injection belongs to the group of medicines called vinca alkaloids used alone or in combination with other anti-cancer medicines to treat non-small cell lung cancer that has spread to other body parts and advanced breast cancer that has not responded to other medicines.

Vinrel 50mg Injection contains Vinorelbine, which works by stopping or slowing the growth of cancer cells in the body.

In some cases, Vinrel 50mg Injection may cause side effects such as nausea, vomiting, constipation, injection site reactions, and a decrease in white and red blood cells. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Vinrel 50mg Injection if you are pregnant, breastfeeding, or think you may be pregnant. Vinrel 50mg Injection is not recommended for children below 18 years. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Vinrel 50mg Injection

Treatment of Non-small cell lung cancer and breast cancer

Medicinal Benefits

Vinrel 50mg Injection belongs to the group of medicines called vinca alkaloids used to treat locally advanced or metastatic non-small cell lung cancer and advanced breast cancer that has not responded to other medicines. It may also be used to treat cancer of the oesophagus and soft tissue sarcoma (cancer that forms in the muscles). Vinrel 50mg Injection contains Vinorelbine, which works by stopping the growth and multiplication of cancer cells. 

Directions for Use

Vinrel 50mg Injection will be administered by a doctor with experience in the use of chemotherapy medications.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Vinrel 50mg Injection

  • Nausea
  • Vomiting
  • Constipation
  • Injection site reactions like redness, burning pain, inflammation of veins, or vein discolouration
  • A decrease in red or white blood cells
  • Weakness of lower extremities
  • Liver disorders (abnormal liver tests)

Drug Warnings

Do not use Vinrel 50mg Injection if you are allergic to any of its components, if you are pregnant, think you might be pregnant or breastfeeding, if you have low white blood cell count, have/had a severe infection within two weeks, have thrombocytopenia (low platelet count), or if you have taken or plan to receive yellow fever vaccination. Inform the doctor if you have a history of heart attack, severe chest pain, liver problems, and signs or symptoms of infection. Consult the doctor immediately if you become pregnant during treatment with Vinrel 50mg Injection. Seek immediate medical attention if you experience symptoms of pulmonary embolism (chest pain, breathlessness, and fainting), posterior reversible encephalopathy syndrome (headaches, changed mental state which may lead to confusion and coma, convulsions, blurred vision and high blood pressure), infection (cough, fever, and chills), severe constipation with abdominal pain, acute respiratory distress syndrome (difficulty breathing), severe reduced blood pressure (severe dizziness and lightheadedness when you stand up), severe chest pain, or allergic reactions (dizziness, rash, swelling of the eyelids, face, lips or throat).

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking anticoagulants, anti-epileptics (phenytoin), antifungals (itraconazole, ketoconazole), anti-cancer (mitomycin C), immunosuppressants (tacrolimus, ciclosporin).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have asthma, severe liver problems, severe infection, or heart problems.

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • MITOMYCIN
  • TACROLIMUS
  • CICLOSPORIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods like spinach, lettuce, squashes, broccoli, nuts, seeds, beans, whole wheat pasta, whole wheat bread, brown rice and fruits.

Special Advise

  • Your doctor may advise regular blood tests before and during treatment with Vinrel 50mg Injection to check if it is safe for you to receive the treatment.
  • Inform the doctor if you are due to take any vaccinations, as many vaccines (live attenuated vaccines) are not recommended during treatment with Vinrel 50mg Injection.
  • Women of childbearing potential must use effective contraception during treatment and for seven months after the end of the treatment.
  • If you are a man being treated with Vinrel 50mg Injection, discuss with the doctor about sperm conservation. Men are advised to use effective contraception during treatment and for four months after the end of the treatment. 

Disease/Condition Glossary

Non-small cell lung cancer: It is a disease in which cancer cells form in the tissues of the lungs. Smoking is the major risk factor for non-small cell lung cancer. Symptoms include a cough that does not go away and shortness of breath.

Breast cancer: It is a type of cancer that develops in the breast when the cells grow abnormally. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.

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Alcohol

Consult your doctor

It is not known if alcohol affects Vinrel 50mg Injection. Please consult your doctor.

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Pregnancy

Unsafe

Do not use Vinrel 50mg Injection if you are pregnant or think you may be pregnant. Consult the doctor immediately if you become pregnant during treatment with Vinrel 50mg Injection.

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Breast Feeding

Unsafe

Do not take Vinrel 50mg Injection if you are breastfeeding. Breastfeeding must be discontinued if treatment with Vinrel 50mg Injection is necessary.

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Driving

Caution

In a few people, Vinrel 50mg Injection may cause dizziness or lightheadedness. Do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Vinrel 50mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a history of kidney diseases, inform your doctor before receiving Vinrel 50mg Injection.

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Children

Unsafe

Vinrel 50mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established.

Country of origin

India
Other Info - VI60204

Author Details

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FAQs

Vinrel 50mg Injection is used to treat Non-small cell lung cancer and breast cancer.
Vinrel 50mg Injection works by stopping or slowing the growth of cancer cells in the body.
Use effective contraception and avoid fathering a child during treatment with Vinrel 50mg Injection and four months after the end of the treatment. Discuss with the doctor about sperm conservation prior to treatment with Vinrel 50mg Injection, as it may alter your fertility.
Vinrel 50mg Injection may cause a severe decrease in white blood cells in the bone marrow. This might increase the risk of developing serious infections. Your doctor may advise regular tests to check the number of white blood cells in your body. Consult the doctor immediately if you experience fever, cough, congestion, sore throat or other signs of infection.
Vinrel 50mg Injection may cause constipation. Consult your doctor if you experience constipation; the doctor may advise about changing your diet or using medicines to prevent/treat constipation.
Vinrel 50mg Injection is a vesicant. It can cause injection site reactions and extravasation hazards. These can be reduced by shortening the infusion time and flushing with IV fluid.
Yes, Vinrel 50mg Injection is effective in the treatment of non-small cell lung cancer and breast cancer. However, its effectiveness may vary from person to person.
Generally, Vinrel 50mg Injection is administered intravenously by a doctor with experience in using chemotherapy medications. Do not self-administer.
Vinrel 50mg Injection may cause hair loss. If you experience hair loss while on treatment with Vinrel 50mg Injection consult your doctor.
The common side effects of Vinrel 50mg Injection may include nausea, vomiting, constipation, injection site reactions, bleeding gums, constipation, cough, and stomach pain or tenderness. Do not be reluctant to talk with your doctor if any side effects persist or worsen.

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